Le SIDA en Afrique subsaharienne (serveur d'exploration)

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<title xml:lang="en">Barriers to Sustaining Antiretroviral Treatment in Kisesa, Tanzania</title>
<author>
<name sortKey="Roura, Maria" sort="Roura, Maria" uniqKey="Roura M" first="Maria" last="Roura">Maria Roura</name>
<affiliation>
<nlm:aff id="A1">Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Busza, Joanna" sort="Busza, Joanna" uniqKey="Busza J" first="Joanna" last="Busza">Joanna Busza</name>
<affiliation>
<nlm:aff id="A1">Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wringe, Alison" sort="Wringe, Alison" uniqKey="Wringe A" first="Alison" last="Wringe">Alison Wringe</name>
<affiliation>
<nlm:aff id="A1">Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Mbata, Doris" sort="Mbata, Doris" uniqKey="Mbata D" first="Doris" last="Mbata">Doris Mbata</name>
<affiliation>
<nlm:aff id="A2">The Tanzanian National Institute for Medical Research, Mwanza, Tanzania</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Urassa, Mark" sort="Urassa, Mark" uniqKey="Urassa M" first="Mark" last="Urassa">Mark Urassa</name>
<affiliation>
<nlm:aff id="A2">The Tanzanian National Institute for Medical Research, Mwanza, Tanzania</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Zaba, Basia" sort="Zaba, Basia" uniqKey="Zaba B" first="Basia" last="Zaba">Basia Zaba</name>
<affiliation>
<nlm:aff id="A1">Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</nlm:aff>
</affiliation>
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<idno type="pmid">19866538</idno>
<idno type="pmc">2776987</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776987</idno>
<idno type="RBID">PMC:2776987</idno>
<idno type="doi">10.1089/apc.2008.0129</idno>
<date when="2009">2009</date>
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<title xml:lang="en" level="a" type="main">Barriers to Sustaining Antiretroviral Treatment in Kisesa, Tanzania</title>
<author>
<name sortKey="Roura, Maria" sort="Roura, Maria" uniqKey="Roura M" first="Maria" last="Roura">Maria Roura</name>
<affiliation>
<nlm:aff id="A1">Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Busza, Joanna" sort="Busza, Joanna" uniqKey="Busza J" first="Joanna" last="Busza">Joanna Busza</name>
<affiliation>
<nlm:aff id="A1">Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wringe, Alison" sort="Wringe, Alison" uniqKey="Wringe A" first="Alison" last="Wringe">Alison Wringe</name>
<affiliation>
<nlm:aff id="A1">Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Mbata, Doris" sort="Mbata, Doris" uniqKey="Mbata D" first="Doris" last="Mbata">Doris Mbata</name>
<affiliation>
<nlm:aff id="A2">The Tanzanian National Institute for Medical Research, Mwanza, Tanzania</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Urassa, Mark" sort="Urassa, Mark" uniqKey="Urassa M" first="Mark" last="Urassa">Mark Urassa</name>
<affiliation>
<nlm:aff id="A2">The Tanzanian National Institute for Medical Research, Mwanza, Tanzania</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Zaba, Basia" sort="Zaba, Basia" uniqKey="Zaba B" first="Basia" last="Zaba">Basia Zaba</name>
<affiliation>
<nlm:aff id="A1">Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">AIDS patient care and STDs</title>
<idno type="ISSN">1087-2914</idno>
<idno type="eISSN">1557-7449</idno>
<imprint>
<date when="2009">2009</date>
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</series>
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<div type="abstract" xml:lang="en">
<p id="P1">Two years after the introduction of free antiretroviral therapy (ART) in Tanzania and in spite of the logistical support provided to facilitate clinic attendance, a considerable level of attrition from the program was identified among clients from a semi-rural ward. Qualitative research on ART patients’ health-seeking behavior identified factors affecting sustained attendance at treatment clinics. A mix of methods was used for data collection including semi-structured interviews with 42 clients and 11 service providers and 4 participatory group activities conducted with members of a post-test group between October and December 2006. A socio-ecological framework guided data analysis to categorize facilitators and barriers into individual, social, programmatic, and structural level influences, and subsequently explored their interaction and relative significance in shaping ART clients’ behavior. Our findings suggest that personal motivation and self-efficacy contribute to program retention, and are affected by other individual-level experiences such as perceived health benefits or disease severity. However, these determinants are influenced by others’ opinions and beliefs in the community, and constrained by programmatic and structural barriers. Individuals can develop the requisite willingness to sustain strict treatment requirements in a challenging context, but are more likely to do so within supportive family and community environments. Effectiveness and sustainability of ART roll-out could be strengthened by strategic intervention at different levels, with particular attention to community-level factors such as social networks’ influence and support.</p>
</div>
</front>
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<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-journal-id">9607225</journal-id>
<journal-id journal-id-type="pubmed-jr-id">21399</journal-id>
<journal-id journal-id-type="nlm-ta">AIDS Patient Care STDS</journal-id>
<journal-id journal-id-type="iso-abbrev">AIDS Patient Care STDS</journal-id>
<journal-title-group>
<journal-title>AIDS patient care and STDs</journal-title>
</journal-title-group>
<issn pub-type="ppub">1087-2914</issn>
<issn pub-type="epub">1557-7449</issn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">19866538</article-id>
<article-id pub-id-type="pmc">2776987</article-id>
<article-id pub-id-type="doi">10.1089/apc.2008.0129</article-id>
<article-id pub-id-type="manuscript">UKMS3956</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Barriers to Sustaining Antiretroviral Treatment in Kisesa, Tanzania</article-title>
<subtitle>A Follow-Up Study to Understand Attrition from the Antiretroviral Program</subtitle>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Roura</surname>
<given-names>Maria</given-names>
</name>
<degrees>Ph.D.</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Busza</surname>
<given-names>Joanna</given-names>
</name>
<degrees>M.Sc.</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Wringe</surname>
<given-names>Alison</given-names>
</name>
<degrees>Ph.D.</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mbata</surname>
<given-names>Doris</given-names>
</name>
<degrees>M.D.</degrees>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Urassa</surname>
<given-names>Mark</given-names>
</name>
<degrees>M.Sc.</degrees>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Zaba</surname>
<given-names>Basia</given-names>
</name>
<degrees>M.Sc.</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
</contrib-group>
<aff id="A1">
<label>1</label>
Centre for Population Studies, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, U.K.</aff>
<aff id="A2">
<label>2</label>
The Tanzanian National Institute for Medical Research, Mwanza, Tanzania</aff>
<author-notes>
<corresp id="CR1">Address reprint request to: Maria Roura, Ph.D., Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, University of London, Mwanza, Tanzania, E-mail:
<email>maria.roura@lshtm.ac.uk</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted">
<day>20</day>
<month>2</month>
<year>2009</year>
</pub-date>
<pub-date pub-type="ppub">
<month>3</month>
<year>2009</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>14</day>
<month>11</month>
<year>2009</year>
</pub-date>
<volume>23</volume>
<issue>3</issue>
<fpage>203</fpage>
<lpage>210</lpage>
<permissions>
<copyright-statement>© Mary Ann Liebert, Inc.</copyright-statement>
</permissions>
<abstract>
<p id="P1">Two years after the introduction of free antiretroviral therapy (ART) in Tanzania and in spite of the logistical support provided to facilitate clinic attendance, a considerable level of attrition from the program was identified among clients from a semi-rural ward. Qualitative research on ART patients’ health-seeking behavior identified factors affecting sustained attendance at treatment clinics. A mix of methods was used for data collection including semi-structured interviews with 42 clients and 11 service providers and 4 participatory group activities conducted with members of a post-test group between October and December 2006. A socio-ecological framework guided data analysis to categorize facilitators and barriers into individual, social, programmatic, and structural level influences, and subsequently explored their interaction and relative significance in shaping ART clients’ behavior. Our findings suggest that personal motivation and self-efficacy contribute to program retention, and are affected by other individual-level experiences such as perceived health benefits or disease severity. However, these determinants are influenced by others’ opinions and beliefs in the community, and constrained by programmatic and structural barriers. Individuals can develop the requisite willingness to sustain strict treatment requirements in a challenging context, but are more likely to do so within supportive family and community environments. Effectiveness and sustainability of ART roll-out could be strengthened by strategic intervention at different levels, with particular attention to community-level factors such as social networks’ influence and support.</p>
</abstract>
<funding-group>
<award-group>
<funding-source country="United Kingdom">Wellcome Trust : </funding-source>
<award-id>084292 || WT</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>

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