Determinants of Engagement in HIV Treatment and Care among Zambians new to Antiretroviral Therapy
Identifieur interne : 001E75 ( Pmc/Corpus ); précédent : 001E74; suivant : 001E76Determinants of Engagement in HIV Treatment and Care among Zambians new to Antiretroviral Therapy
Auteurs : Deborah L. Jones ; Isaac Zulu ; Szonja Vamos ; Ryan Cook ; Ndashi Chitalu ; Stephen M. WeissSource :
- The Journal of the Association of Nurses in AIDS Care : JANAC [ 1055-3290 ] ; 2012.
Abstract
This pilot study assessed the determinants of engagement in HIV care among Zambian patients new to antiretroviral (ARV) therapy, and the effect of an intervention to increase medication adherence. Participants (
Url:
DOI: 10.1016/j.jana.2012.06.009
PubMed: 23009738
PubMed Central: 3543485
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PMC:3543485Le document en format XML
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<author><name sortKey="Jones, Deborah L" sort="Jones, Deborah L" uniqKey="Jones D" first="Deborah L." last="Jones">Deborah L. Jones</name>
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<author><name sortKey="Zulu, Isaac" sort="Zulu, Isaac" uniqKey="Zulu I" first="Isaac" last="Zulu">Isaac Zulu</name>
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<author><name sortKey="Vamos, Szonja" sort="Vamos, Szonja" uniqKey="Vamos S" first="Szonja" last="Vamos">Szonja Vamos</name>
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<author><name sortKey="Cook, Ryan" sort="Cook, Ryan" uniqKey="Cook R" first="Ryan" last="Cook">Ryan Cook</name>
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<author><name sortKey="Chitalu, Ndashi" sort="Chitalu, Ndashi" uniqKey="Chitalu N" first="Ndashi" last="Chitalu">Ndashi Chitalu</name>
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<author><name sortKey="Weiss, Stephen M" sort="Weiss, Stephen M" uniqKey="Weiss S" first="Stephen M." last="Weiss">Stephen M. Weiss</name>
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<author><name sortKey="Zulu, Isaac" sort="Zulu, Isaac" uniqKey="Zulu I" first="Isaac" last="Zulu">Isaac Zulu</name>
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<author><name sortKey="Vamos, Szonja" sort="Vamos, Szonja" uniqKey="Vamos S" first="Szonja" last="Vamos">Szonja Vamos</name>
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<author><name sortKey="Cook, Ryan" sort="Cook, Ryan" uniqKey="Cook R" first="Ryan" last="Cook">Ryan Cook</name>
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<author><name sortKey="Chitalu, Ndashi" sort="Chitalu, Ndashi" uniqKey="Chitalu N" first="Ndashi" last="Chitalu">Ndashi Chitalu</name>
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<series><title level="j">The Journal of the Association of Nurses in AIDS Care : JANAC</title>
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<front><div type="abstract" xml:lang="en"><p id="P1">This pilot study assessed the determinants of engagement in HIV care among Zambian patients new to antiretroviral (ARV) therapy, and the effect of an intervention to increase medication adherence. Participants (<italic>n</italic>
= 160) were randomized to a 3-month group or individual intervention utilizing a crossover design. Psychophysiological (depression, cognitive functioning, health status), social (social support, disclosure, stigma), and structural (health care access, patient-provider communication) factors and treatment engagement (adherence to clinic visits and medication) were assessed. Participants initially receiving group intervention improved their adherence, but gains were not maintained following crossover to the individual intervention. Increased social support and patient-provider communication and decreased concern about HIV medications predicted increased clinic attendance across both arms. Results suggest that early participation in a group intervention may promote increased adherence among patients new to therapy, but long-term engagement in care may be sustained by both one-on-one and group interventions by health care staff.</p>
</div>
</front>
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<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9111870</journal-id>
<journal-id journal-id-type="pubmed-jr-id">1225</journal-id>
<journal-id journal-id-type="nlm-ta">J Assoc Nurses AIDS Care</journal-id>
<journal-id journal-id-type="iso-abbrev">J Assoc Nurses AIDS Care</journal-id>
<journal-title-group><journal-title>The Journal of the Association of Nurses in AIDS Care : JANAC</journal-title>
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<issn pub-type="ppub">1055-3290</issn>
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<article-id pub-id-type="doi">10.1016/j.jana.2012.06.009</article-id>
<article-id pub-id-type="manuscript">NIHMS409817</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
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<title-group><article-title>Determinants of Engagement in HIV Treatment and Care among Zambians new to Antiretroviral Therapy</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Jones</surname>
<given-names>Deborah L.</given-names>
</name>
<degrees>Ph.D.</degrees>
<role>Professor</role>
<aff id="A1">Dept. of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Zulu</surname>
<given-names>Isaac</given-names>
</name>
<degrees>MD</degrees>
<role>Doctor of Infectious Diseases</role>
<aff id="A2">Center for Disease Control & Prevention Lusaka, Zambia</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Vamos</surname>
<given-names>Szonja</given-names>
</name>
<degrees>MA</degrees>
<role>Research Associate</role>
<aff id="A3">Dept. of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine Miami, FL, USA</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Cook</surname>
<given-names>Ryan</given-names>
</name>
<degrees>BA</degrees>
<role>Research Assistant</role>
<aff id="A4">Dept. of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Chitalu</surname>
<given-names>Ndashi</given-names>
</name>
<degrees>MD, MPH</degrees>
<role>Doctor of Pediatrics</role>
<aff id="A5">University Teaching Hospital Lusaka, Zambia</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Weiss</surname>
<given-names>Stephen M.</given-names>
</name>
<degrees>PhD, MPH</degrees>
<role>Professor</role>
<aff id="A6">Dept. of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine Miami, FL, USA</aff>
</contrib>
</contrib-group>
<pub-date pub-type="nihms-submitted"><day>25</day>
<month>9</month>
<year>2012</year>
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<pub-date pub-type="epub"><day>23</day>
<month>9</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="ppub"><season>Sep-Oct</season>
<year>2013</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>01</day>
<month>9</month>
<year>2014</year>
</pub-date>
<volume>24</volume>
<issue>5</issue>
<fpage>e1</fpage>
<lpage>e12</lpage>
<permissions><copyright-statement>© 2012 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.</copyright-statement>
<copyright-year>2012</copyright-year>
</permissions>
<abstract><p id="P1">This pilot study assessed the determinants of engagement in HIV care among Zambian patients new to antiretroviral (ARV) therapy, and the effect of an intervention to increase medication adherence. Participants (<italic>n</italic>
= 160) were randomized to a 3-month group or individual intervention utilizing a crossover design. Psychophysiological (depression, cognitive functioning, health status), social (social support, disclosure, stigma), and structural (health care access, patient-provider communication) factors and treatment engagement (adherence to clinic visits and medication) were assessed. Participants initially receiving group intervention improved their adherence, but gains were not maintained following crossover to the individual intervention. Increased social support and patient-provider communication and decreased concern about HIV medications predicted increased clinic attendance across both arms. Results suggest that early participation in a group intervention may promote increased adherence among patients new to therapy, but long-term engagement in care may be sustained by both one-on-one and group interventions by health care staff.</p>
</abstract>
<kwd-group><kwd>behavioral intervention</kwd>
<kwd>engagement in care</kwd>
<kwd>HIV</kwd>
<kwd>medication adherence</kwd>
<kwd>Zambia</kwd>
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<funding-group><award-group><funding-source country="United States">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</funding-source>
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