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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Domestic violence and prevention of mother-to-child transmission of HIV-1</title>
<author><name sortKey="Kiarie, James N" sort="Kiarie, James N" uniqKey="Kiarie J" first="James N." last="Kiarie">James N. Kiarie</name>
<affiliation><nlm:aff id="A1">Department of Obstetrics/Gynaecology, University of Nairobi, Nairobi, Kenya.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Farquhar, Carey" sort="Farquhar, Carey" uniqKey="Farquhar C" first="Carey" last="Farquhar">Carey Farquhar</name>
<affiliation><nlm:aff id="A3">Department of Medicine, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A4">Department of Epidemiology, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Richardson, Barbra A" sort="Richardson, Barbra A" uniqKey="Richardson B" first="Barbra A." last="Richardson">Barbra A. Richardson</name>
<affiliation><nlm:aff id="A5">Department of Biostatistics, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A6">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, USA.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kabura, Marjory N" sort="Kabura, Marjory N" uniqKey="Kabura M" first="Marjory N." last="Kabura">Marjory N. Kabura</name>
<affiliation><nlm:aff id="A1">Department of Obstetrics/Gynaecology, University of Nairobi, Nairobi, Kenya.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="John, Francis N" sort="John, Francis N" uniqKey="John F" first="Francis N." last="John">Francis N. John</name>
<affiliation><nlm:aff id="A1">Department of Obstetrics/Gynaecology, University of Nairobi, Nairobi, Kenya.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nduati, Ruth W" sort="Nduati, Ruth W" uniqKey="Nduati R" first="Ruth W." last="Nduati">Ruth W. Nduati</name>
<affiliation><nlm:aff id="A2">Department of Paediatrics, University of Nairobi, Nairobi, Kenya.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="John Stewart, Grace C" sort="John Stewart, Grace C" uniqKey="John Stewart G" first="Grace C." last="John-Stewart">Grace C. John-Stewart</name>
<affiliation><nlm:aff id="A3">Department of Medicine, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A4">Department of Epidemiology, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">16931941</idno>
<idno type="pmc">3384736</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384736</idno>
<idno type="RBID">PMC:3384736</idno>
<idno type="doi">10.1097/01.aids.0000242823.51754.0c</idno>
<date when="2006">2006</date>
<idno type="wicri:Area/Pmc/Corpus">001D30</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001D30</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Domestic violence and prevention of mother-to-child transmission of HIV-1</title>
<author><name sortKey="Kiarie, James N" sort="Kiarie, James N" uniqKey="Kiarie J" first="James N." last="Kiarie">James N. Kiarie</name>
<affiliation><nlm:aff id="A1">Department of Obstetrics/Gynaecology, University of Nairobi, Nairobi, Kenya.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Farquhar, Carey" sort="Farquhar, Carey" uniqKey="Farquhar C" first="Carey" last="Farquhar">Carey Farquhar</name>
<affiliation><nlm:aff id="A3">Department of Medicine, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A4">Department of Epidemiology, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Richardson, Barbra A" sort="Richardson, Barbra A" uniqKey="Richardson B" first="Barbra A." last="Richardson">Barbra A. Richardson</name>
<affiliation><nlm:aff id="A5">Department of Biostatistics, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A6">Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, USA.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kabura, Marjory N" sort="Kabura, Marjory N" uniqKey="Kabura M" first="Marjory N." last="Kabura">Marjory N. Kabura</name>
<affiliation><nlm:aff id="A1">Department of Obstetrics/Gynaecology, University of Nairobi, Nairobi, Kenya.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="John, Francis N" sort="John, Francis N" uniqKey="John F" first="Francis N." last="John">Francis N. John</name>
<affiliation><nlm:aff id="A1">Department of Obstetrics/Gynaecology, University of Nairobi, Nairobi, Kenya.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Nduati, Ruth W" sort="Nduati, Ruth W" uniqKey="Nduati R" first="Ruth W." last="Nduati">Ruth W. Nduati</name>
<affiliation><nlm:aff id="A2">Department of Paediatrics, University of Nairobi, Nairobi, Kenya.</nlm:aff>
</affiliation>
</author>
<author><name sortKey="John Stewart, Grace C" sort="John Stewart, Grace C" uniqKey="John Stewart G" first="Grace C." last="John-Stewart">Grace C. John-Stewart</name>
<affiliation><nlm:aff id="A3">Department of Medicine, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A4">Department of Epidemiology, University of Washington, Seattle, USA.</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">AIDS (London, England)</title>
<idno type="ISSN">0269-9370</idno>
<idno type="eISSN">1473-5571</idno>
<imprint><date when="2006">2006</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objectives</title>
<p id="P1">To determine the prevalence of life-time domestic violence by the current partner before HIV-1 testing, its impact on the uptake of prevention of mother-to-child transmission (PMTCT) interventions and frequency after testing.</p>
</sec>
<sec id="S2"><title>Design</title>
<p id="P2">A prospective cohort.</p>
</sec>
<sec id="S3"><title>Methods</title>
<p id="P3">Antenatally, women and their partners were interviewed regarding physical, financial, and psychological abuse by the male partner before HIV-1 testing and 2 weeks after receiving results.</p>
</sec>
<sec id="S4"><title>Results</title>
<p id="P4">Before testing, 804 of 2836 women (28%) reported previous domestic violence, which tended to be associated with increased odds of HIV-1 infection [univariate odds ratio (OR) 1.7, 95% confidence interval (CI) 1.3–2.2; <italic>P</italic>
< 0.0001, adjusted OR 1.2, 95% CI 0.9–1.6; <italic>P</italic>
= 0.1], decreased odds of coming with partners for counseling (adjusted OR 0.7, 95% CI 0.5–1.0; <italic>P</italic>
= 0.04), and decreased odds of partner notification (adjusted OR 0.7, 95% CI 0.5–1.1; <italic>P</italic>
= 0.09). Previous domestic violence was not associated with a reduced uptake of HIV-1 counseling, HIV-1 testing, or nevirapine. After receiving results, 15 out of 1638 women (0.9%) reported domestic violence. After notifying partners of results, the odds of HIV-1-seropositive women reporting domestic violence were 4.8 times those of HIV-1-seronegative women (95% CI 1.4–16; <italic>P</italic>
= 0.01). Compared with women, men reported similar or more male-perpetrated domestic violence, suggesting a cultural acceptability of violence.</p>
</sec>
<sec id="S5"><title>Conclusion</title>
<p id="P5">Domestic violence before testing may limit partner involvement in PMTCT. Although infrequent, immediate post-test domestic violence is more common among HIV-1-infected than uninfected women. Domestic violence prevention programmes need to be integrated into PMTCT, particularly for HIV-1-seropositive women.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8710219</journal-id>
<journal-id journal-id-type="pubmed-jr-id">1493</journal-id>
<journal-id journal-id-type="nlm-ta">AIDS</journal-id>
<journal-id journal-id-type="iso-abbrev">AIDS</journal-id>
<journal-title-group><journal-title>AIDS (London, England)</journal-title>
</journal-title-group>
<issn pub-type="ppub">0269-9370</issn>
<issn pub-type="epub">1473-5571</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">16931941</article-id>
<article-id pub-id-type="pmc">3384736</article-id>
<article-id pub-id-type="doi">10.1097/01.aids.0000242823.51754.0c</article-id>
<article-id pub-id-type="manuscript">NIHMS359164</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Domestic violence and prevention of mother-to-child transmission of HIV-1</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Kiarie</surname>
<given-names>James N.</given-names>
</name>
<xref ref-type="aff" rid="A1">a</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Farquhar</surname>
<given-names>Carey</given-names>
</name>
<xref ref-type="aff" rid="A3">c</xref>
<xref ref-type="aff" rid="A4">d</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Richardson</surname>
<given-names>Barbra A.</given-names>
</name>
<xref ref-type="aff" rid="A5">e</xref>
<xref ref-type="aff" rid="A6">f</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kabura</surname>
<given-names>Marjory N.</given-names>
</name>
<xref ref-type="aff" rid="A1">a</xref>
</contrib>
<contrib contrib-type="author"><name><surname>John</surname>
<given-names>Francis N.</given-names>
</name>
<xref ref-type="aff" rid="A1">a</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Nduati</surname>
<given-names>Ruth W.</given-names>
</name>
<xref ref-type="aff" rid="A2">b</xref>
</contrib>
<contrib contrib-type="author"><name><surname>John-Stewart</surname>
<given-names>Grace C.</given-names>
</name>
<xref ref-type="aff" rid="A3">c</xref>
<xref ref-type="aff" rid="A4">d</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>a</label>
Department of Obstetrics/Gynaecology, University of Nairobi, Nairobi, Kenya.</aff>
<aff id="A2"><label>b</label>
Department of Paediatrics, University of Nairobi, Nairobi, Kenya.</aff>
<aff id="A3"><label>c</label>
Department of Medicine, University of Washington, Seattle, USA.</aff>
<aff id="A4"><label>d</label>
Department of Epidemiology, University of Washington, Seattle, USA.</aff>
<aff id="A5"><label>e</label>
Department of Biostatistics, University of Washington, Seattle, USA.</aff>
<aff id="A6"><label>f</label>
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, USA.</aff>
<author-notes><corresp id="CR1">Correspondence and requests for reprints to James N. Kiarie, University of Nairobi, P.O. Box 3085-00506, Nairobi, Kenya. Tel: +254 202 715607; fax: +254 202 710164; <email>jkiarie@swiftkenya.com</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>12</day>
<month>6</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="ppub"><day>22</day>
<month>8</month>
<year>2006</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>27</day>
<month>6</month>
<year>2012</year>
</pub-date>
<volume>20</volume>
<issue>13</issue>
<fpage>1763</fpage>
<lpage>1769</lpage>
<permissions><copyright-statement>© 2006 Lippincott Williams & Wilkins</copyright-statement>
<copyright-year>2006</copyright-year>
</permissions>
<abstract><sec id="S1"><title>Objectives</title>
<p id="P1">To determine the prevalence of life-time domestic violence by the current partner before HIV-1 testing, its impact on the uptake of prevention of mother-to-child transmission (PMTCT) interventions and frequency after testing.</p>
</sec>
<sec id="S2"><title>Design</title>
<p id="P2">A prospective cohort.</p>
</sec>
<sec id="S3"><title>Methods</title>
<p id="P3">Antenatally, women and their partners were interviewed regarding physical, financial, and psychological abuse by the male partner before HIV-1 testing and 2 weeks after receiving results.</p>
</sec>
<sec id="S4"><title>Results</title>
<p id="P4">Before testing, 804 of 2836 women (28%) reported previous domestic violence, which tended to be associated with increased odds of HIV-1 infection [univariate odds ratio (OR) 1.7, 95% confidence interval (CI) 1.3–2.2; <italic>P</italic>
< 0.0001, adjusted OR 1.2, 95% CI 0.9–1.6; <italic>P</italic>
= 0.1], decreased odds of coming with partners for counseling (adjusted OR 0.7, 95% CI 0.5–1.0; <italic>P</italic>
= 0.04), and decreased odds of partner notification (adjusted OR 0.7, 95% CI 0.5–1.1; <italic>P</italic>
= 0.09). Previous domestic violence was not associated with a reduced uptake of HIV-1 counseling, HIV-1 testing, or nevirapine. After receiving results, 15 out of 1638 women (0.9%) reported domestic violence. After notifying partners of results, the odds of HIV-1-seropositive women reporting domestic violence were 4.8 times those of HIV-1-seronegative women (95% CI 1.4–16; <italic>P</italic>
= 0.01). Compared with women, men reported similar or more male-perpetrated domestic violence, suggesting a cultural acceptability of violence.</p>
</sec>
<sec id="S5"><title>Conclusion</title>
<p id="P5">Domestic violence before testing may limit partner involvement in PMTCT. Although infrequent, immediate post-test domestic violence is more common among HIV-1-infected than uninfected women. Domestic violence prevention programmes need to be integrated into PMTCT, particularly for HIV-1-seropositive women.</p>
</sec>
</abstract>
<kwd-group><kwd>Adverse effects</kwd>
<kwd>Africa</kwd>
<kwd>domestic violence</kwd>
<kwd>HIV</kwd>
<kwd>vertical transmission</kwd>
<kwd>prevention of mother-to-child transmission</kwd>
</kwd-group>
<funding-group><award-group><funding-source country="United States">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</funding-source>
<award-id>P30 AI027757-12 || AI</award-id>
</award-group>
<award-group><funding-source country="United States">National Institute of Child Health & Human Development : NICHD</funding-source>
<award-id>K24 HD054314 || HD</award-id>
</award-group>
<award-group><funding-source country="United States">Fogarty International Center : FIC</funding-source>
<award-id>D43 TW000007 || TW</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>
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