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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Qualitative Analysis of the Effects of Depression and Antidepressants on Physical and Work Functioning among ART Clients in Uganda</title><author><name sortKey="Ngo, Victoria K" sort="Ngo, Victoria K" uniqKey="Ngo V" first="Victoria K." last="Ngo">Victoria K. Ngo</name><affiliation><nlm:aff id="A1">RAND Corporation, Santa Monica, USA</nlm:aff></affiliation></author><author><name sortKey="Wagner, Glenn J" sort="Wagner, Glenn J" uniqKey="Wagner G" first="Glenn J." last="Wagner">Glenn J. Wagner</name><affiliation><nlm:aff id="A1">RAND Corporation, Santa Monica, USA</nlm:aff></affiliation></author><author><name sortKey="Huynh, Alexis" sort="Huynh, Alexis" uniqKey="Huynh A" first="Alexis" last="Huynh">Alexis Huynh</name><affiliation><nlm:aff id="A1">RAND Corporation, Santa Monica, USA</nlm:aff></affiliation></author><author><name sortKey="Ryan, Gery" sort="Ryan, Gery" uniqKey="Ryan G" first="Gery" last="Ryan">Gery Ryan</name><affiliation><nlm:aff id="A1">RAND Corporation, Santa Monica, USA</nlm:aff></affiliation></author><author><name sortKey="Musisi, Seggane" sort="Musisi, Seggane" uniqKey="Musisi S" first="Seggane" last="Musisi">Seggane Musisi</name><affiliation><nlm:aff id="A2">Makerere University, Kampala, Uganda</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23442495</idno><idno type="pmc">3830664</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830664</idno><idno type="RBID">PMC:3830664</idno><idno type="doi">10.1177/2325957412471992</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">001B03</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001B03</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A Qualitative Analysis of the Effects of Depression and Antidepressants on Physical and Work Functioning among ART Clients in Uganda</title><author><name sortKey="Ngo, Victoria K" sort="Ngo, Victoria K" uniqKey="Ngo V" first="Victoria K." last="Ngo">Victoria K. Ngo</name><affiliation><nlm:aff id="A1">RAND Corporation, Santa Monica, USA</nlm:aff></affiliation></author><author><name sortKey="Wagner, Glenn J" sort="Wagner, Glenn J" uniqKey="Wagner G" first="Glenn J." last="Wagner">Glenn J. Wagner</name><affiliation><nlm:aff id="A1">RAND Corporation, Santa Monica, USA</nlm:aff></affiliation></author><author><name sortKey="Huynh, Alexis" sort="Huynh, Alexis" uniqKey="Huynh A" first="Alexis" last="Huynh">Alexis Huynh</name><affiliation><nlm:aff id="A1">RAND Corporation, Santa Monica, USA</nlm:aff></affiliation></author><author><name sortKey="Ryan, Gery" sort="Ryan, Gery" uniqKey="Ryan G" first="Gery" last="Ryan">Gery Ryan</name><affiliation><nlm:aff id="A1">RAND Corporation, Santa Monica, USA</nlm:aff></affiliation></author><author><name sortKey="Musisi, Seggane" sort="Musisi, Seggane" uniqKey="Musisi S" first="Seggane" last="Musisi">Seggane Musisi</name><affiliation><nlm:aff id="A2">Makerere University, Kampala, Uganda</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of the International Association of Providers of AIDS Care</title><idno type="ISSN">2325-9574</idno><idno type="eISSN">2325-9582</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Depression is common among people living with HIV/AIDS in sub-Saharan Africa. Yet, little is known about how depression influences physical health and socioeconomic well-being in the context of antiretroviral therapy (ART). Semi-structured interviews with 40 adult HIV clients receiving ART in Uganda were conducted to assess experiences prior to and after HIV diagnosis and initiation of ART. Content analysis revealed themes that were suggestive of the following patterns: 1) functioning decreased after patients were diagnosed with HIV, but improved following ART, 2) depression is associated with lower physical health functioning and work status levels after both HIV diagnosis and ART, and 3) antidepressant medication is associated with better functioning compared to depressed patients not receiving depression treatment. These findings suggest that depression plays a role in the deleterious effects of HIV on functioning, and that antidepressant treatment provided alongside ART may serve to help individuals regain functioning, particularly employment. These findings highlight the potential value of integrating depression treatment into HIV care.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101603896</journal-id><journal-id journal-id-type="pubmed-jr-id">41074</journal-id><journal-id journal-id-type="nlm-ta">J Int Assoc Provid AIDS Care</journal-id><journal-id journal-id-type="iso-abbrev">J Int Assoc Provid AIDS Care</journal-id><journal-title-group><journal-title>Journal of the International Association of Providers of AIDS Care</journal-title></journal-title-group><issn pub-type="ppub">2325-9574</issn><issn pub-type="epub">2325-9582</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23442495</article-id><article-id pub-id-type="pmc">3830664</article-id><article-id pub-id-type="doi">10.1177/2325957412471992</article-id><article-id pub-id-type="manuscript">NIHMS497994</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>A Qualitative Analysis of the Effects of Depression and Antidepressants on Physical and Work Functioning among ART Clients in Uganda</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ngo</surname><given-names>Victoria K.</given-names></name><degrees>Ph.D</degrees><xref ref-type="aff" rid="A1">a</xref></contrib><contrib contrib-type="author"><name><surname>Wagner</surname><given-names>Glenn J.</given-names></name><degrees>Ph.D</degrees><xref ref-type="aff" rid="A1">a</xref></contrib><contrib contrib-type="author"><name><surname>Huynh</surname><given-names>Alexis</given-names></name><degrees>MPH</degrees><xref ref-type="aff" rid="A1">a</xref></contrib><contrib contrib-type="author"><name><surname>Ryan</surname><given-names>Gery</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A1">a</xref></contrib><contrib contrib-type="author"><name><surname>Musisi</surname><given-names>Seggane</given-names></name><degrees>MBChB</degrees><xref ref-type="aff" rid="A2">b</xref></contrib></contrib-group><aff id="A1"><label>a</label>RAND Corporation, Santa Monica, USA</aff><aff id="A2"><label>b</label>Makerere University, Kampala, Uganda</aff><author-notes><corresp id="FN1">Address reprint requests to: Victoria K. Ngo at RAND Corporation, 1776 Main St., P.O. Box 2138, Santa Monica, CA 90407 or <email>vngo@rand.org</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>1</day><month>8</month><year>2013</year></pub-date><pub-date pub-type="epub"><day>26</day><month>2</month><year>2013</year></pub-date><pub-date pub-type="ppub"><season>Nov-Dec</season><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>17</day><month>11</month><year>2013</year></pub-date><volume>12</volume><issue>6</issue><elocation-id>10.1177/2325957412471992</elocation-id><abstract><p id="P1">Depression is common among people living with HIV/AIDS in sub-Saharan Africa. Yet, little is known about how depression influences physical health and socioeconomic well-being in the context of antiretroviral therapy (ART). Semi-structured interviews with 40 adult HIV clients receiving ART in Uganda were conducted to assess experiences prior to and after HIV diagnosis and initiation of ART. Content analysis revealed themes that were suggestive of the following patterns: 1) functioning decreased after patients were diagnosed with HIV, but improved following ART, 2) depression is associated with lower physical health functioning and work status levels after both HIV diagnosis and ART, and 3) antidepressant medication is associated with better functioning compared to depressed patients not receiving depression treatment. These findings suggest that depression plays a role in the deleterious effects of HIV on functioning, and that antidepressant treatment provided alongside ART may serve to help individuals regain functioning, particularly employment. These findings highlight the potential value of integrating depression treatment into HIV care.</p></abstract><kwd-group><kwd>depression treatment</kwd><kwd>work functioning</kwd><kwd>antiretroviral treatment</kwd><kwd>HIV</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source><award-id>R01 MH083568 || MH</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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