Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of injectable contraceptive use on response to antiretroviral therapy among women in Rakai, Uganda</title><author><name sortKey="Polis, Chelsea B" sort="Polis, Chelsea B" uniqKey="Polis C" first="Chelsea B." last="Polis">Chelsea B. Polis</name><affiliation><nlm:aff id="A1">Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA</nlm:aff></affiliation></author><author><name sortKey="Nakigozi, Gertrude" sort="Nakigozi, Gertrude" uniqKey="Nakigozi G" first="Gertrude" last="Nakigozi">Gertrude Nakigozi</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Ssempijja, Victor" sort="Ssempijja, Victor" uniqKey="Ssempijja V" first="Victor" last="Ssempijja">Victor Ssempijja</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Makumbi, Fredrick E" sort="Makumbi, Fredrick E" uniqKey="Makumbi F" first="Fredrick E." last="Makumbi">Fredrick E. Makumbi</name><affiliation><nlm:aff id="A3">Makerere University, College of Health Sciences, School of Public Health, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Boaz, Iga" sort="Boaz, Iga" uniqKey="Boaz I" first="Iga" last="Boaz">Iga Boaz</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Reynolds, Steven J" sort="Reynolds, Steven J" uniqKey="Reynolds S" first="Steven J." last="Reynolds">Steven J. Reynolds</name><affiliation><nlm:aff id="A4">National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A5">Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA</nlm:aff></affiliation></author><author><name sortKey="Ndyanabo, Anthony" sort="Ndyanabo, Anthony" uniqKey="Ndyanabo A" first="Anthony" last="Ndyanabo">Anthony Ndyanabo</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Lutalo, Tom" sort="Lutalo, Tom" uniqKey="Lutalo T" first="Tom" last="Lutalo">Tom Lutalo</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Wawer, Maria J" sort="Wawer, Maria J" uniqKey="Wawer M" first="Maria J." last="Wawer">Maria J. Wawer</name><affiliation><nlm:aff id="A1">Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA</nlm:aff></affiliation></author><author><name sortKey="Gray, Ronald H" sort="Gray, Ronald H" uniqKey="Gray R" first="Ronald H." last="Gray">Ronald H. Gray</name><affiliation><nlm:aff id="A1">Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22717186</idno><idno type="pmc">3449005</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449005</idno><idno type="RBID">PMC:3449005</idno><idno type="doi">10.1016/j.contraception.2012.05.001</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">001821</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001821</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effect of injectable contraceptive use on response to antiretroviral therapy among women in Rakai, Uganda</title><author><name sortKey="Polis, Chelsea B" sort="Polis, Chelsea B" uniqKey="Polis C" first="Chelsea B." last="Polis">Chelsea B. Polis</name><affiliation><nlm:aff id="A1">Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA</nlm:aff></affiliation></author><author><name sortKey="Nakigozi, Gertrude" sort="Nakigozi, Gertrude" uniqKey="Nakigozi G" first="Gertrude" last="Nakigozi">Gertrude Nakigozi</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Ssempijja, Victor" sort="Ssempijja, Victor" uniqKey="Ssempijja V" first="Victor" last="Ssempijja">Victor Ssempijja</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Makumbi, Fredrick E" sort="Makumbi, Fredrick E" uniqKey="Makumbi F" first="Fredrick E." last="Makumbi">Fredrick E. Makumbi</name><affiliation><nlm:aff id="A3">Makerere University, College of Health Sciences, School of Public Health, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Boaz, Iga" sort="Boaz, Iga" uniqKey="Boaz I" first="Iga" last="Boaz">Iga Boaz</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Reynolds, Steven J" sort="Reynolds, Steven J" uniqKey="Reynolds S" first="Steven J." last="Reynolds">Steven J. Reynolds</name><affiliation><nlm:aff id="A4">National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A5">Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA</nlm:aff></affiliation></author><author><name sortKey="Ndyanabo, Anthony" sort="Ndyanabo, Anthony" uniqKey="Ndyanabo A" first="Anthony" last="Ndyanabo">Anthony Ndyanabo</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Lutalo, Tom" sort="Lutalo, Tom" uniqKey="Lutalo T" first="Tom" last="Lutalo">Tom Lutalo</name><affiliation><nlm:aff id="A2">Rakai Health Sciences Program, Kalisizo, Uganda</nlm:aff></affiliation></author><author><name sortKey="Wawer, Maria J" sort="Wawer, Maria J" uniqKey="Wawer M" first="Maria J." last="Wawer">Maria J. Wawer</name><affiliation><nlm:aff id="A1">Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA</nlm:aff></affiliation></author><author><name sortKey="Gray, Ronald H" sort="Gray, Ronald H" uniqKey="Gray R" first="Ronald H." last="Gray">Ronald H. Gray</name><affiliation><nlm:aff id="A1">Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA</nlm:aff></affiliation></author></analytic><series><title level="j">Contraception</title><idno type="ISSN">0010-7824</idno><idno type="eISSN">1879-0518</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title><p id="P2">There is limited evidence on the effect of injectable contraception on response to antiretroviral therapy (ART).</p></sec><sec id="S2"><title>Design</title><p id="P3">Using modified Poisson regression, we assessed data from 418 female Ugandan ART initiators to examine the effect of injectable contraceptive use on a composite virologic failure outcome (defined as failure to achieve virologic suppression, switch to second line therapy, or death within 12 months of ART initiation), and also assessed ART adherence.</p></sec><sec id="S3"><title>Results</title><p id="P4">About 12% of women reported using injectable contraceptives at ART initiation, and their composite virologic failure rates 12 months later were similar to women not using injectable contraceptives at ART initiation (11% vs. 12%, p=0.99). Multivariable Poisson regression suggested no significant differences in virologic failure by injectable contraceptive use at baseline (PRR: 0.85, p=0.71), but power was limited. Adherence to ART increased with time since ART initiation, but did not appear to differ between injectable contraceptive users and non-users.</p></sec><sec id="S4"><title>Conclusions</title><p id="P5">Consistent with current WHO guidelines, our results suggest no deleterious effect of injectable contraceptive use on response to ART, but power was limited, injectable contraceptive use patterns over time were inconsistent, and additional evidence is needed.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">0234361</journal-id><journal-id journal-id-type="pubmed-jr-id">3163</journal-id><journal-id journal-id-type="nlm-ta">Contraception</journal-id><journal-id journal-id-type="iso-abbrev">Contraception</journal-id><journal-title-group><journal-title>Contraception</journal-title></journal-title-group><issn pub-type="ppub">0010-7824</issn><issn pub-type="epub">1879-0518</issn></journal-meta><article-meta><article-id pub-id-type="pmid">22717186</article-id><article-id pub-id-type="pmc">3449005</article-id><article-id pub-id-type="doi">10.1016/j.contraception.2012.05.001</article-id><article-id pub-id-type="manuscript">NIHMS376097</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Effect of injectable contraceptive use on response to antiretroviral therapy among women in Rakai, Uganda</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Polis</surname><given-names>Chelsea B.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref rid="FN1" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Nakigozi</surname><given-names>Gertrude</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Ssempijja</surname><given-names>Victor</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Makumbi</surname><given-names>Fredrick E.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Boaz</surname><given-names>Iga</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Reynolds</surname><given-names>Steven J.</given-names></name><xref ref-type="aff" rid="A4">4</xref><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Ndyanabo</surname><given-names>Anthony</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Lutalo</surname><given-names>Tom</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Wawer</surname><given-names>Maria J.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Gray</surname><given-names>Ronald H.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib></contrib-group><aff id="A1"><label>1</label>Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, 21205, USA</aff><aff id="A2"><label>2</label>Rakai Health Sciences Program, Kalisizo, Uganda</aff><aff id="A3"><label>3</label>Makerere University, College of Health Sciences, School of Public Health, Kampala, Uganda</aff><aff id="A4"><label>4</label>National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA</aff><aff id="A5"><label>5</label>Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA</aff><author-notes><corresp id="FN1"><label>*</label>Corresponding author: Chelsea Polis, 1391 Pennsylvania Ave SE, Unit 417, Washington, DC 20003, <email>cpolis@jhsph.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>17</day><month>5</month><year>2012</year></pub-date><pub-date pub-type="epub"><day>18</day><month>6</month><year>2012</year></pub-date><pub-date pub-type="ppub"><month>12</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>12</month><year>2013</year></pub-date><volume>86</volume><issue>6</issue><fpage>725</fpage><lpage>730</lpage><permissions><copyright-statement>© 2012 Elsevier Inc. All rights reserved.</copyright-statement><copyright-year>2012</copyright-year></permissions><abstract><sec id="S1"><title>Background</title><p id="P2">There is limited evidence on the effect of injectable contraception on response to antiretroviral therapy (ART).</p></sec><sec id="S2"><title>Design</title><p id="P3">Using modified Poisson regression, we assessed data from 418 female Ugandan ART initiators to examine the effect of injectable contraceptive use on a composite virologic failure outcome (defined as failure to achieve virologic suppression, switch to second line therapy, or death within 12 months of ART initiation), and also assessed ART adherence.</p></sec><sec id="S3"><title>Results</title><p id="P4">About 12% of women reported using injectable contraceptives at ART initiation, and their composite virologic failure rates 12 months later were similar to women not using injectable contraceptives at ART initiation (11% vs. 12%, p=0.99). Multivariable Poisson regression suggested no significant differences in virologic failure by injectable contraceptive use at baseline (PRR: 0.85, p=0.71), but power was limited. Adherence to ART increased with time since ART initiation, but did not appear to differ between injectable contraceptive users and non-users.</p></sec><sec id="S4"><title>Conclusions</title><p id="P5">Consistent with current WHO guidelines, our results suggest no deleterious effect of injectable contraceptive use on response to ART, but power was limited, injectable contraceptive use patterns over time were inconsistent, and additional evidence is needed.</p></sec></abstract><kwd-group><kwd>family planning</kwd><kwd>hormonal contraception</kwd><kwd>injectable contraception</kwd><kwd>HIV</kwd><kwd>antiretroviral therapy</kwd><kwd>Uganda</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</funding-source><award-id>U01 AI075115 || AI</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaSubSaharaV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001821 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001821 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= SidaSubSaharaV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.32. |  |