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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neonatal Mortality in HIV-Exposed Infants Born to Women Receiving Combination Antiretroviral Therapy in Rural Uganda</title><author><name sortKey="Ades, Veronica" sort="Ades, Veronica" uniqKey="Ades V" first="Veronica" last="Ades">Veronica Ades</name><affiliation><nlm:aff id="fmt044-AFF1">Department of Obstetrics and Gynecology, New York University, New York, NY 10016, USA</nlm:aff></affiliation></author><author><name sortKey="Mwesigwa, Julia" sort="Mwesigwa, Julia" uniqKey="Mwesigwa J" first="Julia" last="Mwesigwa">Julia Mwesigwa</name><affiliation><nlm:aff id="fmt044-AFF2">Infectious Diseases Research Collaboration, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Natureeba, Paul" sort="Natureeba, Paul" uniqKey="Natureeba P" first="Paul" last="Natureeba">Paul Natureeba</name><affiliation><nlm:aff id="fmt044-AFF2">Infectious Diseases Research Collaboration, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Clark, Tamara D" sort="Clark, Tamara D" uniqKey="Clark T" first="Tamara D." last="Clark">Tamara D. Clark</name><affiliation><nlm:aff id="fmt044-AFF3">Department of Medicine, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Plenty, Albert" sort="Plenty, Albert" uniqKey="Plenty A" first="Albert" last="Plenty">Albert Plenty</name><affiliation><nlm:aff id="fmt044-AFF3">Department of Medicine, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Charlebois, Edwin" sort="Charlebois, Edwin" uniqKey="Charlebois E" first="Edwin" last="Charlebois">Edwin Charlebois</name><affiliation><nlm:aff id="fmt044-AFF3">Department of Medicine, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Achan, Jane" sort="Achan, Jane" uniqKey="Achan J" first="Jane" last="Achan">Jane Achan</name><affiliation><nlm:aff id="fmt044-AFF4">Department of Pediatrics, Makerere University College of Health Sciences, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Kamya, Moses R" sort="Kamya, Moses R" uniqKey="Kamya M" first="Moses R." last="Kamya">Moses R. Kamya</name><affiliation><nlm:aff id="fmt044-AFF5">Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Havlir, Diane V" sort="Havlir, Diane V" uniqKey="Havlir D" first="Diane V." last="Havlir">Diane V. Havlir</name><affiliation><nlm:aff id="fmt044-AFF3">Department of Medicine, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Cohan, Deborah" sort="Cohan, Deborah" uniqKey="Cohan D" first="Deborah" last="Cohan">Deborah Cohan</name><affiliation><nlm:aff id="fmt044-AFF6">Obstetrics and Gynecology, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Ruel, Theodore D" sort="Ruel, Theodore D" uniqKey="Ruel T" first="Theodore D." last="Ruel">Theodore D. Ruel</name><affiliation><nlm:aff id="fmt044-AFF7">Department of Pediatrics, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23764539</idno><idno type="pmc">3842848</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3842848</idno><idno type="RBID">PMC:3842848</idno><idno type="doi">10.1093/tropej/fmt044</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">001714</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001714</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Neonatal Mortality in HIV-Exposed Infants Born to Women Receiving Combination Antiretroviral Therapy in Rural Uganda</title><author><name sortKey="Ades, Veronica" sort="Ades, Veronica" uniqKey="Ades V" first="Veronica" last="Ades">Veronica Ades</name><affiliation><nlm:aff id="fmt044-AFF1">Department of Obstetrics and Gynecology, New York University, New York, NY 10016, USA</nlm:aff></affiliation></author><author><name sortKey="Mwesigwa, Julia" sort="Mwesigwa, Julia" uniqKey="Mwesigwa J" first="Julia" last="Mwesigwa">Julia Mwesigwa</name><affiliation><nlm:aff id="fmt044-AFF2">Infectious Diseases Research Collaboration, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Natureeba, Paul" sort="Natureeba, Paul" uniqKey="Natureeba P" first="Paul" last="Natureeba">Paul Natureeba</name><affiliation><nlm:aff id="fmt044-AFF2">Infectious Diseases Research Collaboration, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Clark, Tamara D" sort="Clark, Tamara D" uniqKey="Clark T" first="Tamara D." last="Clark">Tamara D. Clark</name><affiliation><nlm:aff id="fmt044-AFF3">Department of Medicine, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Plenty, Albert" sort="Plenty, Albert" uniqKey="Plenty A" first="Albert" last="Plenty">Albert Plenty</name><affiliation><nlm:aff id="fmt044-AFF3">Department of Medicine, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Charlebois, Edwin" sort="Charlebois, Edwin" uniqKey="Charlebois E" first="Edwin" last="Charlebois">Edwin Charlebois</name><affiliation><nlm:aff id="fmt044-AFF3">Department of Medicine, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Achan, Jane" sort="Achan, Jane" uniqKey="Achan J" first="Jane" last="Achan">Jane Achan</name><affiliation><nlm:aff id="fmt044-AFF4">Department of Pediatrics, Makerere University College of Health Sciences, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Kamya, Moses R" sort="Kamya, Moses R" uniqKey="Kamya M" first="Moses R." last="Kamya">Moses R. Kamya</name><affiliation><nlm:aff id="fmt044-AFF5">Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda</nlm:aff></affiliation></author><author><name sortKey="Havlir, Diane V" sort="Havlir, Diane V" uniqKey="Havlir D" first="Diane V." last="Havlir">Diane V. Havlir</name><affiliation><nlm:aff id="fmt044-AFF3">Department of Medicine, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Cohan, Deborah" sort="Cohan, Deborah" uniqKey="Cohan D" first="Deborah" last="Cohan">Deborah Cohan</name><affiliation><nlm:aff id="fmt044-AFF6">Obstetrics and Gynecology, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author><author><name sortKey="Ruel, Theodore D" sort="Ruel, Theodore D" uniqKey="Ruel T" first="Theodore D." last="Ruel">Theodore D. Ruel</name><affiliation><nlm:aff id="fmt044-AFF7">Department of Pediatrics, University of California, San Francisco, CA 94143, USA</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Tropical Pediatrics</title><idno type="ISSN">0142-6338</idno><idno type="eISSN">1465-3664</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>As human immunodeficiency virus (HIV)-infected women gain access to combination antiretroviral therapy throughout sub-Saharan Africa, a growing number of infants are being born HIV-exposed but uninfected. Data about neonatal mortality and the impact of premature delivery, in this population are limited. We describe the 28-day mortality outcomes in a cohort of HIV-exposed infants who had ultrasound-confirmed gestational age in rural Uganda. There were 13 deaths among 351 infants, including 9 deaths in the perinatal period. Premature delivery was a strong predictor of mortality. The prevention of HIV transmission to infants is now possible in rural low-resource settings but the frequency of neonatal death among HIV-exposed infants remains extremely high, calling for new comprehensive interventions to reduce mortality in this growing population.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Trop Pediatr</journal-id><journal-id journal-id-type="iso-abbrev">J. Trop. Pediatr</journal-id><journal-id journal-id-type="publisher-id">tropej</journal-id><journal-id journal-id-type="hwp">tropej</journal-id><journal-title-group><journal-title>Journal of Tropical Pediatrics</journal-title></journal-title-group><issn pub-type="ppub">0142-6338</issn><issn pub-type="epub">1465-3664</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23764539</article-id><article-id pub-id-type="pmc">3842848</article-id><article-id pub-id-type="doi">10.1093/tropej/fmt044</article-id><article-id pub-id-type="publisher-id">fmt044</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Papers</subject></subj-group></article-categories><title-group><article-title>Neonatal Mortality in HIV-Exposed Infants Born to Women Receiving Combination Antiretroviral Therapy in Rural Uganda</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Ades</surname><given-names>Veronica</given-names></name><xref ref-type="aff" rid="fmt044-AFF1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Mwesigwa</surname><given-names>Julia</given-names></name><xref ref-type="aff" rid="fmt044-AFF2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Natureeba</surname><given-names>Paul</given-names></name><xref ref-type="aff" rid="fmt044-AFF2"><sup>2</sup></xref></contrib><contrib contrib-type="author"><name><surname>Clark</surname><given-names>Tamara D.</given-names></name><xref ref-type="aff" rid="fmt044-AFF3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Plenty</surname><given-names>Albert</given-names></name><xref ref-type="aff" rid="fmt044-AFF3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Charlebois</surname><given-names>Edwin</given-names></name><xref ref-type="aff" rid="fmt044-AFF3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Achan</surname><given-names>Jane</given-names></name><xref ref-type="aff" rid="fmt044-AFF4"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Kamya</surname><given-names>Moses R.</given-names></name><xref ref-type="aff" rid="fmt044-AFF5"><sup>5</sup></xref></contrib><contrib contrib-type="author"><name><surname>Havlir</surname><given-names>Diane V.</given-names></name><xref ref-type="aff" rid="fmt044-AFF3"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Cohan</surname><given-names>Deborah</given-names></name><xref ref-type="aff" rid="fmt044-AFF6"><sup>6</sup></xref></contrib><contrib contrib-type="author"><name><surname>Ruel</surname><given-names>Theodore D.</given-names></name><xref ref-type="aff" rid="fmt044-AFF7"><sup>7</sup></xref></contrib></contrib-group><aff id="fmt044-AFF1"><sup>1</sup>Department of Obstetrics and Gynecology, New York University, New York, NY 10016, USA</aff><aff id="fmt044-AFF2"><sup>2</sup>Infectious Diseases Research Collaboration, Kampala, Uganda</aff><aff id="fmt044-AFF3"><sup>3</sup>Department of Medicine, University of California, San Francisco, CA 94143, USA</aff><aff id="fmt044-AFF4"><sup>4</sup>Department of Pediatrics, Makerere University College of Health Sciences, Kampala, Uganda</aff><aff id="fmt044-AFF5"><sup>5</sup>Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda</aff><aff id="fmt044-AFF6"><sup>6</sup>Obstetrics and Gynecology, University of California, San Francisco, CA 94143, USA</aff><aff id="fmt044-AFF7"><sup>7</sup>Department of Pediatrics, University of California, San Francisco, CA 94143, USA</aff><author-notes><corresp>Correspondence: Veronica Ades, Department of Obstetrics and Gynecology, New York University, 462 First Avenue, 9th floor, New York, NY 10010, USA. Tel: <phone>(212) 238-7244</phone>. Fax: <fax>(212) 238-7284</fax>. E-mail <<email>veronica.ades@nyumc.org</email>>.</corresp></author-notes><pub-date pub-type="ppub"><month>12</month><year>2013</year></pub-date><pub-date pub-type="epub"><day>13</day><month>6</month><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>12</month><year>2014</year></pub-date><volume>59</volume><issue>6</issue><fpage>441</fpage><lpage>446</lpage><permissions><copyright-statement>© The Author [2013]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com</copyright-statement><copyright-year>2013</copyright-year></permissions><abstract><p>As human immunodeficiency virus (HIV)-infected women gain access to combination antiretroviral therapy throughout sub-Saharan Africa, a growing number of infants are being born HIV-exposed but uninfected. Data about neonatal mortality and the impact of premature delivery, in this population are limited. We describe the 28-day mortality outcomes in a cohort of HIV-exposed infants who had ultrasound-confirmed gestational age in rural Uganda. There were 13 deaths among 351 infants, including 9 deaths in the perinatal period. Premature delivery was a strong predictor of mortality. The prevention of HIV transmission to infants is now possible in rural low-resource settings but the frequency of neonatal death among HIV-exposed infants remains extremely high, calling for new comprehensive interventions to reduce mortality in this growing population.</p></abstract><kwd-group><kwd>HIV</kwd><kwd>neonatal</kwd><kwd>mortality</kwd><kwd>prematurity</kwd><kwd>Africa</kwd></kwd-group><counts><page-count count="6"></page-count></counts></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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