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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">HBV Infection Among HIV-Infected Cohort and HIV-Negative Hospital Attendees in South Western Nigeria</title><author><name sortKey="Adewumi, Moses Olubusuyi" sort="Adewumi, Moses Olubusuyi" uniqKey="Adewumi M" first="Moses Olubusuyi" last="Adewumi">Moses Olubusuyi Adewumi</name><affiliation><nlm:aff id="A1">Department of Virology, College of Medicine, University College Hospital, University of Ibadan, Ibadan, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Donbraye, Emmanuel" sort="Donbraye, Emmanuel" uniqKey="Donbraye E" first="Emmanuel" last="Donbraye">Emmanuel Donbraye</name><affiliation><nlm:aff id="A2">Department of Medical Microbiology and Parasitology, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Sule, Waidi Folorunso" sort="Sule, Waidi Folorunso" uniqKey="Sule W" first="Waidi Folorunso" last="Sule">Waidi Folorunso Sule</name><affiliation><nlm:aff id="A3">Department of Biological Sciences, College of Science, Engineering and Technology, Osun State University, PMB 4494, Oke-Baale, Osogbo, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Olarinde, Olaniran" sort="Olarinde, Olaniran" uniqKey="Olarinde O" first="Olaniran" last="Olarinde">Olaniran Olarinde</name><affiliation><nlm:aff id="A2">Department of Medical Microbiology and Parasitology, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25722846</idno><idno type="pmc">4325354</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325354</idno><idno type="RBID">PMC:4325354</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">001568</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001568</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">HBV Infection Among HIV-Infected Cohort and HIV-Negative Hospital Attendees in South Western Nigeria</title><author><name sortKey="Adewumi, Moses Olubusuyi" sort="Adewumi, Moses Olubusuyi" uniqKey="Adewumi M" first="Moses Olubusuyi" last="Adewumi">Moses Olubusuyi Adewumi</name><affiliation><nlm:aff id="A1">Department of Virology, College of Medicine, University College Hospital, University of Ibadan, Ibadan, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Donbraye, Emmanuel" sort="Donbraye, Emmanuel" uniqKey="Donbraye E" first="Emmanuel" last="Donbraye">Emmanuel Donbraye</name><affiliation><nlm:aff id="A2">Department of Medical Microbiology and Parasitology, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Sule, Waidi Folorunso" sort="Sule, Waidi Folorunso" uniqKey="Sule W" first="Waidi Folorunso" last="Sule">Waidi Folorunso Sule</name><affiliation><nlm:aff id="A3">Department of Biological Sciences, College of Science, Engineering and Technology, Osun State University, PMB 4494, Oke-Baale, Osogbo, Nigeria</nlm:aff></affiliation></author><author><name sortKey="Olarinde, Olaniran" sort="Olarinde, Olaniran" uniqKey="Olarinde O" first="Olaniran" last="Olarinde">Olaniran Olarinde</name><affiliation><nlm:aff id="A2">Department of Medical Microbiology and Parasitology, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria</nlm:aff></affiliation></author></analytic><series><title level="j">African Journal of Infectious Diseases</title><idno type="ISSN">2006-0165</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Prevalence, association and probable mode of acquisition of HBV and HIV dual infections have not been fully explored. Thus, HBV intervention plan and services are sometimes exclusively targeted towards HIV-infected population. We investigated HBV infection among HIV-infected cohort in comparison with HIV-negative hospital attendees to ascertain dual infectivity pattern; thereby encouraging appropriate allotment of intervention services.</p></sec><sec sec-type="materials|methods"><title>Materials and Methods</title><p>A total of 349 (M=141; F=208; Mean=33.98 years; Range= 0.33–80 years) plasma specimens from two virus diagnostic laboratories in south-western Nigeria were analysed. These include 182 HIV-positive and 167 HIV-negative specimens from ART and GDV laboratories respectively. The specimens were initially screened for detectable HIV antigen/antibody, and subsequently HBsAg by ELISA technique.</p></sec><sec sec-type="results"><title>Results</title><p>Overall, HBsAg was detected in 20.92% (95% CI: 16.65–25.19%) of the patients. Also, 24.82% (95% CI: 17.69–31.95%) and 18.27% (95% CI: 13.02–23.52%) HBsAg positivity was recorded for males and females respectively. CHI square analysis showed no association (P=0.14) between gender and prevalence of HBsAg. Similarly, comparison of prevalence of HBsAg by age groups shows no significant difference (P=0.24). Overall, no significant difference (P=0.59) was observed in the prevalence of HBsAg among the HIV-infected cohort and HIV-negative hospital attendees.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>Results of the study confirm endemicity and comparable rates of HBV infection independent of HIV-status.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Afr J Infect Dis</journal-id><journal-id journal-id-type="iso-abbrev">Afr J Infect Dis</journal-id><journal-title-group><journal-title>African Journal of Infectious Diseases</journal-title></journal-title-group><issn pub-type="ppub">2006-0165</issn><publisher><publisher-name>African Ethnomedicines Network</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25722846</article-id><article-id pub-id-type="pmc">4325354</article-id><article-id pub-id-type="publisher-id">jAJID.v9.i1.pg14</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>HBV Infection Among HIV-Infected Cohort and HIV-Negative Hospital Attendees in South Western Nigeria</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Adewumi</surname><given-names>Moses Olubusuyi</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Donbraye</surname><given-names>Emmanuel</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Sule</surname><given-names>Waidi Folorunso</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Olarinde</surname><given-names>Olaniran</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Virology, College of Medicine, University College Hospital, University of Ibadan, Ibadan, Nigeria</aff><aff id="A2"><label>2</label>Department of Medical Microbiology and Parasitology, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria</aff><aff id="A3"><label>3</label>Department of Biological Sciences, College of Science, Engineering and Technology, Osun State University, PMB 4494, Oke-Baale, Osogbo, Nigeria</aff><author-notes><corresp><email>adewumi1@hotmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><year>2015</year></pub-date><volume>9</volume><issue>1</issue><fpage>14</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright © Afr. J. Infect. Diseases 2015</copyright-statement><copyright-year>2015</copyright-year></permissions><abstract abstract-type="executive-summary"><sec><title>Background</title><p>Prevalence, association and probable mode of acquisition of HBV and HIV dual infections have not been fully explored. Thus, HBV intervention plan and services are sometimes exclusively targeted towards HIV-infected population. We investigated HBV infection among HIV-infected cohort in comparison with HIV-negative hospital attendees to ascertain dual infectivity pattern; thereby encouraging appropriate allotment of intervention services.</p></sec><sec sec-type="materials|methods"><title>Materials and Methods</title><p>A total of 349 (M=141; F=208; Mean=33.98 years; Range= 0.33–80 years) plasma specimens from two virus diagnostic laboratories in south-western Nigeria were analysed. These include 182 HIV-positive and 167 HIV-negative specimens from ART and GDV laboratories respectively. The specimens were initially screened for detectable HIV antigen/antibody, and subsequently HBsAg by ELISA technique.</p></sec><sec sec-type="results"><title>Results</title><p>Overall, HBsAg was detected in 20.92% (95% CI: 16.65–25.19%) of the patients. Also, 24.82% (95% CI: 17.69–31.95%) and 18.27% (95% CI: 13.02–23.52%) HBsAg positivity was recorded for males and females respectively. CHI square analysis showed no association (P=0.14) between gender and prevalence of HBsAg. Similarly, comparison of prevalence of HBsAg by age groups shows no significant difference (P=0.24). Overall, no significant difference (P=0.59) was observed in the prevalence of HBsAg among the HIV-infected cohort and HIV-negative hospital attendees.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>Results of the study confirm endemicity and comparable rates of HBV infection independent of HIV-status.</p></sec></abstract><kwd-group><kwd>ART</kwd><kwd>HBV</kwd><kwd>HIV</kwd><kwd>Nigeria</kwd><kwd>Dual positivity</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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