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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Sero-prevalence of herpes simplex type 2 virus (HSV-2) and HIV infection in Kampala, Uganda</title><author><name sortKey="Nakku Joloba, Edith" sort="Nakku Joloba, Edith" uniqKey="Nakku Joloba E" first="Edith" last="Nakku-Joloba">Edith Nakku-Joloba</name><affiliation><nlm:aff id="A1"> Makerere University College of Health Sciences, School of Public Health</nlm:aff></affiliation></author><author><name sortKey="Kambugu, Fred" sort="Kambugu, Fred" uniqKey="Kambugu F" first="Fred" last="Kambugu">Fred Kambugu</name><affiliation><nlm:aff id="A2"> STD Clinic/Ward 12, Mulago National Referral Hospital</nlm:aff></affiliation></author><author><name sortKey="Wasubire, Julius" sort="Wasubire, Julius" uniqKey="Wasubire J" first="Julius" last="Wasubire">Julius Wasubire</name><affiliation><nlm:aff id="A3"> Mbarara University of Science and Technology, Computer Science</nlm:aff></affiliation></author><author><name sortKey="Kimeze, Joshua" sort="Kimeze, Joshua" uniqKey="Kimeze J" first="Joshua" last="Kimeze">Joshua Kimeze</name><affiliation><nlm:aff id="A2"> STD Clinic/Ward 12, Mulago National Referral Hospital</nlm:aff></affiliation></author><author><name sortKey="Salata, Robert" sort="Salata, Robert" uniqKey="Salata R" first="Robert" last="Salata">Robert Salata</name><affiliation><nlm:aff id="A4"> Case Western reserve University, Medicine</nlm:aff></affiliation></author><author><name sortKey="Albert, Jeffrey M" sort="Albert, Jeffrey M" uniqKey="Albert J" first="Jeffrey M" last="Albert">Jeffrey M. Albert</name><affiliation><nlm:aff id="A5"> Case Western Reserve University, Biostatistics</nlm:aff></affiliation></author><author><name sortKey="Rimm, Alfred" sort="Rimm, Alfred" uniqKey="Rimm A" first="Alfred" last="Rimm">Alfred Rimm</name><affiliation><nlm:aff id="A6"> Case Western Reserve University, Epidemiology</nlm:aff></affiliation></author><author><name sortKey="Whalen, Christopher" sort="Whalen, Christopher" uniqKey="Whalen C" first="Christopher" last="Whalen">Christopher Whalen</name><affiliation><nlm:aff id="A7"> University of Georgia, College of Public Health, Epidemiology and Biostatistics</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25834483</idno><idno type="pmc">4370054</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370054</idno><idno type="RBID">PMC:4370054</idno><idno type="doi">10.4314/ahs.v14i4.2</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001539</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001539</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Sero-prevalence of herpes simplex type 2 virus (HSV-2) and HIV infection in Kampala, Uganda</title><author><name sortKey="Nakku Joloba, Edith" sort="Nakku Joloba, Edith" uniqKey="Nakku Joloba E" first="Edith" last="Nakku-Joloba">Edith Nakku-Joloba</name><affiliation><nlm:aff id="A1"> Makerere University College of Health Sciences, School of Public Health</nlm:aff></affiliation></author><author><name sortKey="Kambugu, Fred" sort="Kambugu, Fred" uniqKey="Kambugu F" first="Fred" last="Kambugu">Fred Kambugu</name><affiliation><nlm:aff id="A2"> STD Clinic/Ward 12, Mulago National Referral Hospital</nlm:aff></affiliation></author><author><name sortKey="Wasubire, Julius" sort="Wasubire, Julius" uniqKey="Wasubire J" first="Julius" last="Wasubire">Julius Wasubire</name><affiliation><nlm:aff id="A3"> Mbarara University of Science and Technology, Computer Science</nlm:aff></affiliation></author><author><name sortKey="Kimeze, Joshua" sort="Kimeze, Joshua" uniqKey="Kimeze J" first="Joshua" last="Kimeze">Joshua Kimeze</name><affiliation><nlm:aff id="A2"> STD Clinic/Ward 12, Mulago National Referral Hospital</nlm:aff></affiliation></author><author><name sortKey="Salata, Robert" sort="Salata, Robert" uniqKey="Salata R" first="Robert" last="Salata">Robert Salata</name><affiliation><nlm:aff id="A4"> Case Western reserve University, Medicine</nlm:aff></affiliation></author><author><name sortKey="Albert, Jeffrey M" sort="Albert, Jeffrey M" uniqKey="Albert J" first="Jeffrey M" last="Albert">Jeffrey M. Albert</name><affiliation><nlm:aff id="A5"> Case Western Reserve University, Biostatistics</nlm:aff></affiliation></author><author><name sortKey="Rimm, Alfred" sort="Rimm, Alfred" uniqKey="Rimm A" first="Alfred" last="Rimm">Alfred Rimm</name><affiliation><nlm:aff id="A6"> Case Western Reserve University, Epidemiology</nlm:aff></affiliation></author><author><name sortKey="Whalen, Christopher" sort="Whalen, Christopher" uniqKey="Whalen C" first="Christopher" last="Whalen">Christopher Whalen</name><affiliation><nlm:aff id="A7"> University of Georgia, College of Public Health, Epidemiology and Biostatistics</nlm:aff></affiliation></author></analytic><series><title level="j">African Health Sciences</title><idno type="ISSN">1680-6905</idno><idno type="eISSN">1729-0503</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Prevalence of herpes simplex type 2 virus (HSV-2) is high worldwide. Previous studies in Uganda were rural or in women. We estimated age and sex-specific sero-prevalence of HSV-2 in Kampala, Uganda.</p></sec><sec sec-type="methods"><title>Methods</title><p>Using two-stage random sampling stratified on population density, a survey of persons 15–65 years was conducted. Type-specific serological tests for HSV-2, HSV-1(HerpeSelect2 and 1 ELISA), HIV (Rapid tests and ELISA), syphilis (RPR and TPHA) were done. Additional prevalence analysis included post-stratification weighting on the Uganda 2002 Census gender distribution.</p></sec><sec sec-type="results"><title>Results</title><p>Among 1124 persons, HSV-2 prevalence was 58% (95% CI: 55, 60), HSV-1; 98% (95% CI: 97.6, 99.1), HIV; 17.7% (95% CI: 14.8, 19.2) and syphilis; 1.7% (95% CI: 1.4, 1.9). Weighted HSV-2 prevalence was 53.8% (Women; 63.8%, men; 43.2%), similar to unweighted data. Weighted HIV prevalence was 20.7% in women, 8.6% in men. Of 165 HIV infected persons, 85.4% had HSV-2. Risk factors for HSV-2 were being a woman (OR 2.0; 95% CI: 1.42, 2.78), age (OR 3.3; 95% CI: 2.43, 4.53), education (OR 1.70; 95% CI: 1.34, 2.34) and HIV (OR 4.5; 95% CI: 2.70, 7.50).</p></sec><sec sec-type="conclusions"><title>Conclusion</title><p>Prevalence of HSV-2 and HIV was high especially in women. Syphilis was rare. Awareness of herpes was low. Interventions in young people are needed.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Afr Health Sci</journal-id><journal-id journal-id-type="iso-abbrev">Afr Health Sci</journal-id><journal-title-group><journal-title>African Health Sciences</journal-title></journal-title-group><issn pub-type="ppub">1680-6905</issn><issn pub-type="epub">1729-0503</issn><publisher><publisher-name>Makerere Medical School</publisher-name><publisher-loc>Kampala, Uganda</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25834483</article-id><article-id pub-id-type="pmc">4370054</article-id><article-id pub-id-type="publisher-id">jAFHS.v14.i4.pg782</article-id><article-id pub-id-type="doi">10.4314/ahs.v14i4.2</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Sero-prevalence of herpes simplex type 2 virus (HSV-2) and HIV infection in Kampala, Uganda</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Nakku-Joloba</surname><given-names>Edith</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Kambugu</surname><given-names>Fred</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Wasubire</surname><given-names>Julius</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Kimeze</surname><given-names>Joshua</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Salata</surname><given-names>Robert</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Albert</surname><given-names>Jeffrey M</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Rimm</surname><given-names>Alfred</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Whalen</surname><given-names>Christopher</given-names></name><xref ref-type="aff" rid="A7">7</xref></contrib></contrib-group><aff id="A1"><label>1</label> Makerere University College of Health Sciences, School of Public Health</aff><aff id="A2"><label>2</label> STD Clinic/Ward 12, Mulago National Referral Hospital</aff><aff id="A3"><label>3</label> Mbarara University of Science and Technology, Computer Science</aff><aff id="A4"><label>4</label> Case Western reserve University, Medicine</aff><aff id="A5"><label>5</label> Case Western Reserve University, Biostatistics</aff><aff id="A6"><label>6</label> Case Western Reserve University, Epidemiology</aff><aff id="A7"><label>7</label> University of Georgia, College of Public Health, Epidemiology and Biostatistics</aff><author-notes><corresp>Corresponding author: Edith Nakku-Joloba Makerere University College of Health Sciences, School of Public Health <email>edith.nakkujoloba@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><month>12</month><year>2014</year></pub-date><volume>14</volume><issue>4</issue><fpage>782</fpage><lpage>789</lpage><permissions><copyright-statement>Copyright © Makerere Medical School, Uganda 2014</copyright-statement><copyright-year>2014</copyright-year></permissions><abstract abstract-type="executive-summary"><sec><title>Background</title><p>Prevalence of herpes simplex type 2 virus (HSV-2) is high worldwide. Previous studies in Uganda were rural or in women. We estimated age and sex-specific sero-prevalence of HSV-2 in Kampala, Uganda.</p></sec><sec sec-type="methods"><title>Methods</title><p>Using two-stage random sampling stratified on population density, a survey of persons 15–65 years was conducted. Type-specific serological tests for HSV-2, HSV-1(HerpeSelect2 and 1 ELISA), HIV (Rapid tests and ELISA), syphilis (RPR and TPHA) were done. Additional prevalence analysis included post-stratification weighting on the Uganda 2002 Census gender distribution.</p></sec><sec sec-type="results"><title>Results</title><p>Among 1124 persons, HSV-2 prevalence was 58% (95% CI: 55, 60), HSV-1; 98% (95% CI: 97.6, 99.1), HIV; 17.7% (95% CI: 14.8, 19.2) and syphilis; 1.7% (95% CI: 1.4, 1.9). Weighted HSV-2 prevalence was 53.8% (Women; 63.8%, men; 43.2%), similar to unweighted data. Weighted HIV prevalence was 20.7% in women, 8.6% in men. Of 165 HIV infected persons, 85.4% had HSV-2. Risk factors for HSV-2 were being a woman (OR 2.0; 95% CI: 1.42, 2.78), age (OR 3.3; 95% CI: 2.43, 4.53), education (OR 1.70; 95% CI: 1.34, 2.34) and HIV (OR 4.5; 95% CI: 2.70, 7.50).</p></sec><sec sec-type="conclusions"><title>Conclusion</title><p>Prevalence of HSV-2 and HIV was high especially in women. Syphilis was rare. Awareness of herpes was low. Interventions in young people are needed.</p></sec></abstract><kwd-group><kwd>HSV-2</kwd><kwd>HIV</kwd><kwd>Kampala Uganda</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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