Scaling Up Circumcision Programs in Southern Africa: The Potential Impact of Gender Disparities and Changes in Condom Use Behaviors on Heterosexual HIV Transmission
Identifieur interne : 001130 ( Pmc/Corpus ); précédent : 001129; suivant : 001131Scaling Up Circumcision Programs in Southern Africa: The Potential Impact of Gender Disparities and Changes in Condom Use Behaviors on Heterosexual HIV Transmission
Auteurs : Kyeen M. Andersson ; Douglas K. Owens ; A. David PaltielSource :
- AIDS and behavior [ 1090-7165 ] ; 2011.
Abstract
Circumcision significantly reduces female-to-male transmission of HIV infection, but changes in behavior may influence the overall impact on transmission. We sought to explore these effects, particularly for societies where women have less power to negotiate safe sex. We developed a compartmental epidemic model to simulate the population-level impact of various circumcision programs on heterosexual HIV transmission in Soweto. We incorporated gender-specific negotiation of condom use in sexual partnerships and explored post-circumcision changes in condom use. A 5-year prevention program in which only an additional 10% of uncircumcised males undergo circumcision each year, for example, would prevent 13% of the expected new HIV infections over 20 years. Outcomes were sensitive to potential changes in behavior and differed by gender. For Southern Africa, even modest programs offering circumcision would result in significant benefits. Because decreases in male condom use could diminish these benefits, particularly for women, circumcision programs should emphasize risk-reduction counseling.
Url:
DOI: 10.1007/s10461-010-9784-y
PubMed: 20924783
PubMed Central: 3112296
Links to Exploration step
PMC:3112296Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Scaling Up Circumcision Programs in Southern Africa: The Potential Impact of Gender Disparities and Changes in Condom Use Behaviors on Heterosexual HIV Transmission</title><author><name sortKey="Andersson, Kyeen M" sort="Andersson, Kyeen M" uniqKey="Andersson K" first="Kyeen M." last="Andersson">Kyeen M. Andersson</name></author><author><name sortKey="Owens, Douglas K" sort="Owens, Douglas K" uniqKey="Owens D" first="Douglas K." last="Owens">Douglas K. Owens</name></author><author><name sortKey="Paltiel, A David" sort="Paltiel, A David" uniqKey="Paltiel A" first="A. David" last="Paltiel">A. David Paltiel</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">20924783</idno><idno type="pmc">3112296</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112296</idno><idno type="RBID">PMC:3112296</idno><idno type="doi">10.1007/s10461-010-9784-y</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">001130</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001130</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Scaling Up Circumcision Programs in Southern Africa: The Potential Impact of Gender Disparities and Changes in Condom Use Behaviors on Heterosexual HIV Transmission</title><author><name sortKey="Andersson, Kyeen M" sort="Andersson, Kyeen M" uniqKey="Andersson K" first="Kyeen M." last="Andersson">Kyeen M. Andersson</name></author><author><name sortKey="Owens, Douglas K" sort="Owens, Douglas K" uniqKey="Owens D" first="Douglas K." last="Owens">Douglas K. Owens</name></author><author><name sortKey="Paltiel, A David" sort="Paltiel, A David" uniqKey="Paltiel A" first="A. David" last="Paltiel">A. David Paltiel</name></author></analytic><series><title level="j">AIDS and behavior</title><idno type="ISSN">1090-7165</idno><idno type="eISSN">1573-3254</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Circumcision significantly reduces female-to-male transmission of HIV infection, but changes in behavior may influence the overall impact on transmission. We sought to explore these effects, particularly for societies where women have less power to negotiate safe sex. We developed a compartmental epidemic model to simulate the population-level impact of various circumcision programs on heterosexual HIV transmission in Soweto. We incorporated gender-specific negotiation of condom use in sexual partnerships and explored post-circumcision changes in condom use. A 5-year prevention program in which only an additional 10% of uncircumcised males undergo circumcision each year, for example, would prevent 13% of the expected new HIV infections over 20 years. Outcomes were sensitive to potential changes in behavior and differed by gender. For Southern Africa, even modest programs offering circumcision would result in significant benefits. Because decreases in male condom use could diminish these benefits, particularly for women, circumcision programs should emphasize risk-reduction counseling.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9712133</journal-id><journal-id journal-id-type="pubmed-jr-id">21042</journal-id><journal-id journal-id-type="nlm-ta">AIDS Behav</journal-id><journal-title>AIDS and behavior</journal-title><issn pub-type="ppub">1090-7165</issn><issn pub-type="epub">1573-3254</issn></journal-meta><article-meta><article-id pub-id-type="pmid">20924783</article-id><article-id pub-id-type="pmc">3112296</article-id><article-id pub-id-type="doi">10.1007/s10461-010-9784-y</article-id><article-id pub-id-type="manuscript">NIHMS233103</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Scaling Up Circumcision Programs in Southern Africa: The Potential Impact of Gender Disparities and Changes in Condom Use Behaviors on Heterosexual HIV Transmission</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Andersson</surname><given-names>Kyeen M.</given-names></name><email>kyeen@aya.yale.edu</email><aff id="A1">Division of Health Policy & Administration, Department of Epidemiology & Public Health, Yale University School of Medicine, 60 College Street, New Haven, CT 06510, USA</aff></contrib><contrib contrib-type="author"><name><surname>Owens</surname><given-names>Douglas K.</given-names></name><aff id="A2">VA Palo Alto Health Care System, Palo Alto, CA, USA</aff><aff id="A3">Center for Primary Care and Outcomes Research/Center for Health Policy, Stanford University, Stanford, CA, USA</aff></contrib><contrib contrib-type="author"><name><surname>Paltiel</surname><given-names>A. David</given-names></name><aff id="A4">Division of Health Policy & Administration, Department of Epidemiology & Public Health, Yale University School of Medicine, 60 College Street, New Haven, CT 06510, USA</aff></contrib></contrib-group><pub-date pub-type="nihms-submitted"><day>8</day><month>11</month><year>2010</year></pub-date><pub-date pub-type="ppub"><month>7</month><year>2011</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>7</month><year>2012</year></pub-date><volume>15</volume><issue>5</issue><fpage>938</fpage><lpage>948</lpage><permissions><copyright-statement>© Springer Science+Business Media, LLC 2010</copyright-statement><copyright-year>2010</copyright-year></permissions><abstract><p id="P1">Circumcision significantly reduces female-to-male transmission of HIV infection, but changes in behavior may influence the overall impact on transmission. We sought to explore these effects, particularly for societies where women have less power to negotiate safe sex. We developed a compartmental epidemic model to simulate the population-level impact of various circumcision programs on heterosexual HIV transmission in Soweto. We incorporated gender-specific negotiation of condom use in sexual partnerships and explored post-circumcision changes in condom use. A 5-year prevention program in which only an additional 10% of uncircumcised males undergo circumcision each year, for example, would prevent 13% of the expected new HIV infections over 20 years. Outcomes were sensitive to potential changes in behavior and differed by gender. For Southern Africa, even modest programs offering circumcision would result in significant benefits. Because decreases in male condom use could diminish these benefits, particularly for women, circumcision programs should emphasize risk-reduction counseling.</p></abstract><kwd-group><kwd>Male circumcision</kwd><kwd>Mathematical models</kwd><kwd>HIV prevention</kwd><kwd>Africa</kwd><kwd>Sexual behavior</kwd></kwd-group><contract-num rid="GM1">T32 GM007205-35
||GM</contract-num><contract-num rid="DA1">R01 DA015612-10
||DA</contract-num><contract-num rid="DA1">P20 DA017589-05
||DA</contract-num><contract-sponsor id="GM1">National Institute of General Medical Sciences : NIGMS</contract-sponsor><contract-sponsor id="DA1">National Institute on Drug Abuse : NIDA</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaSubSaharaV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001130 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001130 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= SidaSubSaharaV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé= PMC:3112296
|texte= Scaling Up Circumcision Programs in Southern Africa: The Potential Impact of Gender Disparities and Changes in Condom Use Behaviors on Heterosexual HIV Transmission
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/RBID.i -Sk "pubmed:20924783" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a SidaSubSaharaV1
| This area was generated with Dilib version V0.6.32. |  |