A systematic review of knowledge, attitudes and beliefs about malaria among the South Asian population
Identifieur interne : 000450 ( Pmc/Corpus ); précédent : 000449; suivant : 000451A systematic review of knowledge, attitudes and beliefs about malaria among the South Asian population
Auteurs : Krishna Regmi ; Anju Kunwar ; Leonard OrtegaSource :
- Infection Ecology & Epidemiology [ 2000-8686 ] ; 2016.
Abstract
Malaria is one of the deadliest mosquito-borne diseases in the world. More than 80% of the total populations are at risk of malaria in the 22 countries in Asia and the Pacific. South Asia alone is home to an estimated 1.4 billion people at risk of contracting malaria. Despite the remarkable progress in reducing the burden of malaria, evidence of the disease based on knowledge of the social and cultural contexts from a South Asian perspective is limited. Our objective was to understand the knowledge, attitudes and beliefs about malaria in South Asian communities.
We conducted a systematic literature review, searching six databases, between 1990 and 2015, focusing on knowledge, attitudes and beliefs about malaria in South Asia. Databases were searched using both ‘free terms’ and ‘index terms’ funnelled using Boolean operators and truncations. Inclusion and exclusion criteria were set, and included papers were scrutinised, employing a critical appraisal tool to find the best available evidences to support the study purpose.
Evidence from 32 articles (26 quantitative, four qualitative and two mixed methods). General knowledge and awareness of the disease, its transmission, and control and preventative measures were generally found to be lacking amongst both the general public and healthcare professionals. In addition, the study shows that poor socio-economic factors – including limited access to services due to poor/limited availability – and issues of affordability are considered as major risk factors.
This review suggests the importance of increasing health awareness, mobilising the local or community healthcare professionals, for prevention as well as early detection and effective treatment of malaria among people who are at risk. Malaria is also a disease associated with poverty and socio-cultural factors; therefore, strong political will, wider partnerships between health and non-health sectors, and strengthening health systems’ technical and managerial capabilities at all level of primary healthcare systems, is inevitable.
Url:
DOI: 10.3402/iee.v6.30822
PubMed: 27141987
PubMed Central: 4854845
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PMC:4854845Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A systematic review of knowledge, attitudes and beliefs about malaria among the South Asian population</title><author><name sortKey="Regmi, Krishna" sort="Regmi, Krishna" uniqKey="Regmi K" first="Krishna" last="Regmi">Krishna Regmi</name><affiliation><nlm:aff id="AF0001">Faculty of Health and Social Sciences, Institute for Health Research, University of Bedfordshire, Luton, UK</nlm:aff></affiliation></author><author><name sortKey="Kunwar, Anju" sort="Kunwar, Anju" uniqKey="Kunwar A" first="Anju" last="Kunwar">Anju Kunwar</name><affiliation><nlm:aff id="AF0001">Faculty of Health and Social Sciences, Institute for Health Research, University of Bedfordshire, Luton, UK</nlm:aff></affiliation></author><author><name sortKey="Ortega, Leonard" sort="Ortega, Leonard" uniqKey="Ortega L" first="Leonard" last="Ortega">Leonard Ortega</name><affiliation><nlm:aff id="AF0002">Global Malaria Programme, World Health Organization, Geneva, Switzerland</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27141987</idno><idno type="pmc">4854845</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854845</idno><idno type="RBID">PMC:4854845</idno><idno type="doi">10.3402/iee.v6.30822</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000450</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000450</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A systematic review of knowledge, attitudes and beliefs about malaria among the South Asian population</title><author><name sortKey="Regmi, Krishna" sort="Regmi, Krishna" uniqKey="Regmi K" first="Krishna" last="Regmi">Krishna Regmi</name><affiliation><nlm:aff id="AF0001">Faculty of Health and Social Sciences, Institute for Health Research, University of Bedfordshire, Luton, UK</nlm:aff></affiliation></author><author><name sortKey="Kunwar, Anju" sort="Kunwar, Anju" uniqKey="Kunwar A" first="Anju" last="Kunwar">Anju Kunwar</name><affiliation><nlm:aff id="AF0001">Faculty of Health and Social Sciences, Institute for Health Research, University of Bedfordshire, Luton, UK</nlm:aff></affiliation></author><author><name sortKey="Ortega, Leonard" sort="Ortega, Leonard" uniqKey="Ortega L" first="Leonard" last="Ortega">Leonard Ortega</name><affiliation><nlm:aff id="AF0002">Global Malaria Programme, World Health Organization, Geneva, Switzerland</nlm:aff></affiliation></author></analytic><series><title level="j">Infection Ecology & Epidemiology</title><idno type="eISSN">2000-8686</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background</title><p>Malaria is one of the deadliest mosquito-borne diseases in the world. More than 80% of the total populations are at risk of malaria in the 22 countries in Asia and the Pacific. South Asia alone is home to an estimated 1.4 billion people at risk of contracting malaria. Despite the remarkable progress in reducing the burden of malaria, evidence of the disease based on knowledge of the social and cultural contexts from a South Asian perspective is limited. Our objective was to understand the knowledge, attitudes and beliefs about malaria in South Asian communities.</p></sec><sec id="st2"><title>Methodology</title><p>We conducted a systematic literature review, searching six databases, between 1990 and 2015, focusing on knowledge, attitudes and beliefs about malaria in South Asia. Databases were searched using both ‘free terms’ and ‘index terms’ funnelled using Boolean operators and truncations. Inclusion and exclusion criteria were set, and included papers were scrutinised, employing a critical appraisal tool to find the best available evidences to support the study purpose.</p></sec><sec id="st3"><title>Results and discussion</title><p>Evidence from 32 articles (26 quantitative, four qualitative and two mixed methods). General knowledge and awareness of the disease, its transmission, and control and preventative measures were generally found to be lacking amongst both the general public and healthcare professionals. In addition, the study shows that poor socio-economic factors – including limited access to services due to poor/limited availability – and issues of affordability are considered as major risk factors.</p></sec><sec id="st4"><title>Conclusion</title><p>This review suggests the importance of increasing health awareness, mobilising the local or community healthcare professionals, for prevention as well as early detection and effective treatment of malaria among people who are at risk. Malaria is also a disease associated with poverty and socio-cultural factors; therefore, strong political will, wider partnerships between health and non-health sectors, and strengthening health systems’ technical and managerial capabilities at all level of primary healthcare systems, is inevitable.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Heymann, D" uniqKey="Heymann D">D Heymann</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Rijken, Mj" uniqKey="Rijken M">MJ Rijken</name></author><author><name sortKey="Mcgready, R" uniqKey="Mcgready R">R McGready</name></author><author><name sortKey="Boel, Me" uniqKey="Boel M">ME Boel</name></author><author><name sortKey="Poespoprodjo, R" uniqKey="Poespoprodjo R">R Poespoprodjo</name></author><author><name sortKey="Singh, N" uniqKey="Singh N">N Singh</name></author><author><name sortKey="Syafruddin, D" uniqKey="Syafruddin D">D Syafruddin</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Grietens, Kp" uniqKey="Grietens K">KP Grietens</name></author><author><name sortKey="Xuan, Xn" uniqKey="Xuan X">XN Xuan</name></author><author><name sortKey="Ribera, Jm" uniqKey="Ribera J">JM Ribera</name></author><author><name sortKey="Duc, Tn" uniqKey="Duc T">TN Duc</name></author><author><name sortKey="Bortel, Wv" uniqKey="Bortel W">WV Bortel</name></author><author><name sortKey="Ba, Nt" uniqKey="Ba N">NT Ba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kumar, D" uniqKey="Kumar D">D Kumar</name></author><author><name sortKey="Kumar, M" uniqKey="Kumar M">M Kumar</name></author><author><name sortKey="Kumar, A" uniqKey="Kumar A">A Kumar</name></author><author><name sortKey="Singh, Sk" uniqKey="Singh S">SK Singh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kumar, A" uniqKey="Kumar A">A Kumar</name></author><author><name sortKey="Chery, L" uniqKey="Chery L">L Chery</name></author><author><name sortKey="Biswas, C" uniqKey="Biswas C">C Biswas</name></author><author><name sortKey="Dubhashi, N" uniqKey="Dubhashi N">N Dubhashi</name></author><author><name sortKey="Dutta, P" uniqKey="Dutta P">P Dutta</name></author><author><name sortKey="Kumar, V" uniqKey="Kumar V">V Kumar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leslie, T" uniqKey="Leslie T">T Leslie</name></author><author><name sortKey="Mayan, Mi" uniqKey="Mayan M">MI Mayan</name></author><author><name sortKey="Hasan, Ma" uniqKey="Hasan M">MA Hasan</name></author><author><name sortKey="Safi, Mh" uniqKey="Safi M">MH Safi</name></author><author><name sortKey="Klinkenberg, E" uniqKey="Klinkenberg E">E Klinkenberg</name></author><author><name sortKey="Whitty, Cjm" uniqKey="Whitty C">CJM Whitty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khatoon, L" uniqKey="Khatoon L">L Khatoon</name></author><author><name sortKey="Khan, Iu" uniqKey="Khan I">IU Khan</name></author><author><name sortKey="Shah, Sa" uniqKey="Shah S">SA Shah</name></author><author><name sortKey="Jan, Mi" uniqKey="Jan M">MI Jan</name></author><author><name sortKey="Ullah, F" uniqKey="Ullah F">F Ullah</name></author><author><name sortKey="Malik, Sa" uniqKey="Malik S">SA Malik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rowland, M" uniqKey="Rowland M">M Rowland</name></author><author><name sortKey="Durrani, N" uniqKey="Durrani N">N Durrani</name></author><author><name sortKey="Kenward, M" uniqKey="Kenward M">M Kenward</name></author><author><name sortKey="Mohammed, N" uniqKey="Mohammed N">N Mohammed</name></author><author><name sortKey="Urahman, H" uniqKey="Urahman H">H Urahman</name></author><author><name sortKey="Hewitt, S" uniqKey="Hewitt S">S Hewitt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, R" uniqKey="Sharma R">R Sharma</name></author><author><name sortKey="Thakor, H" uniqKey="Thakor H">H Thakor</name></author><author><name sortKey="Saha, K" uniqKey="Saha K">K Saha</name></author><author><name sortKey="Sonal, G" uniqKey="Sonal G">G Sonal</name></author><author><name sortKey="Dhariwal, A" uniqKey="Dhariwal A">A Dhariwal</name></author><author><name sortKey="Singh, N" uniqKey="Singh N">N Singh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dhillon, Hs" uniqKey="Dhillon H">HS Dhillon</name></author><author><name sortKey="Kar, Sb" uniqKey="Kar S">SB Kar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bates, I" uniqKey="Bates I">I Bates</name></author><author><name sortKey="Fenton, C" uniqKey="Fenton C">C Fenton</name></author><author><name sortKey="Gruber, J" uniqKey="Gruber J">J Gruber</name></author><author><name sortKey="Lalloo, D" uniqKey="Lalloo D">D Lalloo</name></author><author><name sortKey="Lara, Am" uniqKey="Lara A">AM Lara</name></author><author><name sortKey="Medina, Lara A" uniqKey="Medina L">Lara A Medina</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dash, Ap" uniqKey="Dash A">AP Dash</name></author><author><name sortKey="Valecha, N" uniqKey="Valecha N">N Valecha</name></author><author><name sortKey="Anvikar, Ar" uniqKey="Anvikar A">AR Anvikar</name></author><author><name sortKey="Kumar, A" uniqKey="Kumar A">A Kumar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boland, A" uniqKey="Boland A">A Boland</name></author><author><name sortKey="Cherry, M" uniqKey="Cherry M">M Cherry</name></author><author><name sortKey="Dickson, R" uniqKey="Dickson R">R Dickson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mays, N" uniqKey="Mays N">N Mays</name></author><author><name sortKey="Pope, C" uniqKey="Pope C">C Pope</name></author><author><name sortKey="Popay, J" uniqKey="Popay J">J Popay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guyatt, G" uniqKey="Guyatt G">G Guyatt</name></author><author><name sortKey="Rennie, D" uniqKey="Rennie D">D Rennie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garg, Ax" uniqKey="Garg A">AX Garg</name></author><author><name sortKey="Hackam, D" uniqKey="Hackam D">D Hackam</name></author><author><name sortKey="Tonelli, M" uniqKey="Tonelli M">M Tonelli</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Ke" uniqKey="Smith K">KE Smith</name></author><author><name sortKey="Bambra, C" uniqKey="Bambra C">C Bambra</name></author><author><name sortKey="Joyce, Ke" uniqKey="Joyce K">KE Joyce</name></author><author><name sortKey="Perkins, N" uniqKey="Perkins N">N Perkins</name></author><author><name sortKey="Hunter, Dj" uniqKey="Hunter D">DJ Hunter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ahmed, Sm" uniqKey="Ahmed S">SM Ahmed</name></author><author><name sortKey="Haque, R" uniqKey="Haque R">R Haque</name></author><author><name sortKey="Haque, U" uniqKey="Haque U">U Haque</name></author><author><name sortKey="Hossain, A" uniqKey="Hossain A">A Hossain</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ahmed, Sm" uniqKey="Ahmed S">SM Ahmed</name></author><author><name sortKey="Hossain, Sm" uniqKey="Hossain S">SM Hossain</name></author><author><name sortKey="Kabir, M" uniqKey="Kabir M">M Kabir</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ahmed, Sm" uniqKey="Ahmed S">SM Ahmed</name></author><author><name sortKey="Hossain, S" uniqKey="Hossain S">S Hossain</name></author><author><name sortKey="Kabir, Mm" uniqKey="Kabir M">MM Kabir</name></author><author><name sortKey="Roy, S" uniqKey="Roy S">S Roy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anand, T" uniqKey="Anand T">T Anand</name></author><author><name sortKey="Kumar, R" uniqKey="Kumar R">R Kumar</name></author><author><name sortKey="Saini, V" uniqKey="Saini V">V Saini</name></author><author><name sortKey="Meena, G" uniqKey="Meena G">G Meena</name></author><author><name sortKey="Ingle, G" uniqKey="Ingle G">G Ingle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bashar, K" uniqKey="Bashar K">K Bashar</name></author><author><name sortKey="Al Amin, Hm" uniqKey="Al Amin H">HM Al-Amin</name></author><author><name sortKey="Reza, Ms" uniqKey="Reza M">MS Reza</name></author><author><name sortKey="Islam, M" uniqKey="Islam M">M Islam</name></author><author><name sortKey="Asaduzzaman" uniqKey="Asaduzzaman">Asaduzzaman</name></author><author><name sortKey="Ahmed, Tu" uniqKey="Ahmed T">TU Ahmed</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chourasia, Mk" uniqKey="Chourasia M">MK Chourasia</name></author><author><name sortKey="Abraham, Vj" uniqKey="Abraham V">VJ Abraham</name></author><author><name sortKey="John, J" uniqKey="John J">J John</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dambhare, Dg" uniqKey="Dambhare D">DG Dambhare</name></author><author><name sortKey="Nimgade, Sd" uniqKey="Nimgade S">SD Nimgade</name></author><author><name sortKey="Dudhe, Jy" uniqKey="Dudhe J">JY Dudhe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Das, A" uniqKey="Das A">A Das</name></author><author><name sortKey="Ravindran, Ts" uniqKey="Ravindran T">TS Ravindran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Das, A" uniqKey="Das A">A Das</name></author><author><name sortKey="Ravindran, Ts" uniqKey="Ravindran T">TS Ravindran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dhawan, G" uniqKey="Dhawan G">G Dhawan</name></author><author><name sortKey="Joseph, N" uniqKey="Joseph N">N Joseph</name></author><author><name sortKey="Pekow, Ps" uniqKey="Pekow P">PS Pekow</name></author><author><name sortKey="Rogers, Ca" uniqKey="Rogers C">CA Rogers</name></author><author><name sortKey="Poudel, Kc" uniqKey="Poudel K">KC Poudel</name></author><author><name sortKey="Bulzacchelli, Mt" uniqKey="Bulzacchelli M">MT Bulzacchelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fernando, Sd" uniqKey="Fernando S">SD Fernando</name></author><author><name sortKey="Abeyasinghe, Rr" uniqKey="Abeyasinghe R">RR Abeyasinghe</name></author><author><name sortKey="Galappaththy, Gn" uniqKey="Galappaththy G">GN Galappaththy</name></author><author><name sortKey="Gunawardena, N" uniqKey="Gunawardena N">N Gunawardena</name></author><author><name sortKey="Rajapakse, Lc" uniqKey="Rajapakse L">LC Rajapakse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Howard, N" uniqKey="Howard N">N Howard</name></author><author><name sortKey="Shafi, A" uniqKey="Shafi A">A Shafi</name></author><author><name sortKey="Jones, A" uniqKey="Jones A">A Jones</name></author><author><name sortKey="Rowland, M" uniqKey="Rowland M">M Rowland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hussain, Ma" uniqKey="Hussain M">MA Hussain</name></author><author><name sortKey="Dandona, L" uniqKey="Dandona L">L Dandona</name></author><author><name sortKey="Schellenberg, D" uniqKey="Schellenberg D">D Schellenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Joshi, A" uniqKey="Joshi A">A Joshi</name></author><author><name sortKey="Banjara, Mr" uniqKey="Banjara M">MR Banjara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kirkby, K" uniqKey="Kirkby K">K Kirkby</name></author><author><name sortKey="Galappaththy, Gn" uniqKey="Galappaththy G">GN Galappaththy</name></author><author><name sortKey="Kurinczuk, Jj" uniqKey="Kurinczuk J">JJ Kurinczuk</name></author><author><name sortKey="Rajapakse, S" uniqKey="Rajapakse S">S Rajapakse</name></author><author><name sortKey="Fernando, Sd" uniqKey="Fernando S">SD Fernando</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kumar, Ds" uniqKey="Kumar D">DS Kumar</name></author><author><name sortKey="Andimuthu, R" uniqKey="Andimuthu R">R Andimuthu</name></author><author><name sortKey="Rajan, R" uniqKey="Rajan R">R Rajan</name></author><author><name sortKey="Venkatesan, Ms" uniqKey="Venkatesan M">MS Venkatesan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lwin, Mo" uniqKey="Lwin M">MO Lwin</name></author><author><name sortKey="Vijaykumar, S" uniqKey="Vijaykumar S">S Vijaykumar</name></author><author><name sortKey="Lim, G" uniqKey="Lim G">G Lim</name></author><author><name sortKey="Theng, Yl" uniqKey="Theng Y">YL Theng</name></author><author><name sortKey="Foo, S" uniqKey="Foo S">S Foo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nandwani, S" uniqKey="Nandwani S">S Nandwani</name></author><author><name sortKey="Pande, A" uniqKey="Pande A">A Pande</name></author><author><name sortKey="Saluja, M" uniqKey="Saluja M">M Saluja</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pandit, N" uniqKey="Pandit N">N Pandit</name></author><author><name sortKey="Patel, Y" uniqKey="Patel Y">Y Patel</name></author><author><name sortKey="Bhavsar, B" uniqKey="Bhavsar B">B Bhavsar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qayum, M" uniqKey="Qayum M">M Qayum</name></author><author><name sortKey="Zahur, H" uniqKey="Zahur H">H Zahur</name></author><author><name sortKey="Ahmad, N Iiyas M" uniqKey="Ahmad N">N, IIyas M Ahmad</name></author><author><name sortKey="Khan, A" uniqKey="Khan A">A Khan</name></author><author><name sortKey="Khan, S" uniqKey="Khan S">S Khan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sabin, Ll" uniqKey="Sabin L">LL Sabin</name></author><author><name sortKey="Rizal, A" uniqKey="Rizal A">A Rizal</name></author><author><name sortKey="Brooks, Mi" uniqKey="Brooks M">MI Brooks</name></author><author><name sortKey="Singh, Mp" uniqKey="Singh M">MP Singh</name></author><author><name sortKey="Tuchman, J" uniqKey="Tuchman J">J Tuchman</name></author><author><name sortKey="Wylie, Bj" uniqKey="Wylie B">BJ Wylie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saha, Kb" uniqKey="Saha K">KB Saha</name></author><author><name sortKey="Sharma, Rk" uniqKey="Sharma R">RK Sharma</name></author><author><name sortKey="Mishra, R" uniqKey="Mishra R">R Mishra</name></author><author><name sortKey="Verma, R" uniqKey="Verma R">R Verma</name></author><author><name sortKey="Tiwart, Bk" uniqKey="Tiwart B">BK Tiwart</name></author><author><name sortKey="Singh, N" uniqKey="Singh N">N Singh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sarkar, J" uniqKey="Sarkar J">J Sarkar</name></author><author><name sortKey="Murhekar, Mv" uniqKey="Murhekar M">MV Murhekar</name></author><author><name sortKey="Shah, Nk" uniqKey="Shah N">NK Shah</name></author><author><name sortKey="Van Hutin, Y" uniqKey="Van Hutin Y">Y van Hutin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, Rk" uniqKey="Sharma R">RK Sharma</name></author><author><name sortKey="Singh, Mp" uniqKey="Singh M">MP Singh</name></author><author><name sortKey="Saha, Kb" uniqKey="Saha K">KB Saha</name></author><author><name sortKey="Bharti, Pk" uniqKey="Bharti P">PK Bharti</name></author><author><name sortKey="Jain, V" uniqKey="Jain V">V Jain</name></author><author><name sortKey="Singh, Pp" uniqKey="Singh P">PP Singh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sood, Rd" uniqKey="Sood R">RD Sood</name></author><author><name sortKey="Mittal, Pk" uniqKey="Mittal P">PK Mittal</name></author><author><name sortKey="Kapoor, N" uniqKey="Kapoor N">N Kapoor</name></author><author><name sortKey="Razdan, Rk" uniqKey="Razdan R">RK Razdan</name></author><author><name sortKey="Dua, Vk" uniqKey="Dua V">VK Dua</name></author><author><name sortKey="Dash, Ap" uniqKey="Dash A">AP Dash</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sundararajan, R" uniqKey="Sundararajan R">R Sundararajan</name></author><author><name sortKey="Kalkonde, Y" uniqKey="Kalkonde Y">Y Kalkonde</name></author><author><name sortKey="Gokhale, C" uniqKey="Gokhale C">C Gokhale</name></author><author><name sortKey="Greenough, Pg" uniqKey="Greenough P">PG Greenough</name></author><author><name sortKey="Bang, A" uniqKey="Bang A">A Bang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tobgay, T" uniqKey="Tobgay T">T Tobgay</name></author><author><name sortKey="Lhazeen, K" uniqKey="Lhazeen K">K Lhazeen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tobgay, T" uniqKey="Tobgay T">T Tobgay</name></author><author><name sortKey="Pem, D" uniqKey="Pem D">D Pem</name></author><author><name sortKey="Dophu, U" uniqKey="Dophu U">U Dophu</name></author><author><name sortKey="Dumre, Sp" uniqKey="Dumre S">SP Dumre</name></author><author><name sortKey="Na Bangchang, K" uniqKey="Na Bangchang K">K Na-Bangchang</name></author><author><name sortKey="Torres, Ce" uniqKey="Torres C">CE Torres</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vijayakumar, Kn" uniqKey="Vijayakumar K">KN Vijayakumar</name></author><author><name sortKey="Gunasekaran, K" uniqKey="Gunasekaran K">K Gunasekaran</name></author><author><name sortKey="Sahu, Ss" uniqKey="Sahu S">SS Sahu</name></author><author><name sortKey="Jambulingam, P" uniqKey="Jambulingam P">P Jambulingam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yadav, Sp" uniqKey="Yadav S">SP Yadav</name></author><author><name sortKey="Yadav, S" uniqKey="Yadav S">S Yadav</name></author><author><name sortKey="Kuma, P" uniqKey="Kuma P">P Kuma</name></author><author><name sortKey="Yadav, S" uniqKey="Yadav S">S Yadav</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yasuoka, J" uniqKey="Yasuoka J">J Yasuoka</name></author><author><name sortKey="Mangione, Tw" uniqKey="Mangione T">TW Mangione</name></author><author><name sortKey="Spielman, A" uniqKey="Spielman A">A Spielman</name></author><author><name sortKey="Levins, R" uniqKey="Levins R">R Levins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zaidi, Sa" uniqKey="Zaidi S">SA Zaidi</name></author><author><name sortKey="Kokab, F" uniqKey="Kokab F">F Kokab</name></author><author><name sortKey="Bukhari, Ia" uniqKey="Bukhari I">IA Bukhari</name></author><author><name sortKey="Nasir, Ja" uniqKey="Nasir J">JA Nasir</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thomas, J" uniqKey="Thomas J">J Thomas</name></author><author><name sortKey="Harden, A" uniqKey="Harden A">A Harden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ritchie, J" uniqKey="Ritchie J">J Ritchie</name></author><author><name sortKey="Lewis, J" uniqKey="Lewis J">J Lewis</name></author><author><name sortKey="Nicholas, Cm" uniqKey="Nicholas C">CM Nicholas</name></author><author><name sortKey="Ormston, R" uniqKey="Ormston R">R Ormston</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Joff, H" uniqKey="Joff H">H Joff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, Pk" uniqKey="Sharma P">PK Sharma</name></author><author><name sortKey="Sen, Tk" uniqKey="Sen T">TK Sen</name></author><author><name sortKey="Ramakrishnan, R" uniqKey="Ramakrishnan R">R Ramakrishnan</name></author><author><name sortKey="Hutin, Y" uniqKey="Hutin Y">Y Hutin</name></author><author><name sortKey="Gupte, Md" uniqKey="Gupte M">MD Gupte</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mishra, Sk" uniqKey="Mishra S">SK Mishra</name></author><author><name sortKey="Mohanty, S" uniqKey="Mohanty S">S Mohanty</name></author><author><name sortKey="Das, Bs" uniqKey="Das B">BS Das</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Konradsen, F" uniqKey="Konradsen F">F Konradsen</name></author><author><name sortKey="Van Der Hoek, W" uniqKey="Van Der Hoek W">W van der Hoek</name></author><author><name sortKey="Amerasinghe, Ph" uniqKey="Amerasinghe P">PH Amerasinghe</name></author><author><name sortKey="Amerasinghe, Fp" uniqKey="Amerasinghe F">FP Amerasinghe</name></author><author><name sortKey="Fonseka, Kt" uniqKey="Fonseka K">KT Fonseka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Williams, Ha" uniqKey="Williams H">HA Williams</name></author><author><name sortKey="Jones, Co" uniqKey="Jones C">CO Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Udonwa, Ne" uniqKey="Udonwa N">NE Udonwa</name></author><author><name sortKey="Gyuse, An" uniqKey="Gyuse A">AN Gyuse</name></author><author><name sortKey="Etokidem, Aj" uniqKey="Etokidem A">AJ Etokidem</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Midzi, N" uniqKey="Midzi N">N Midzi</name></author><author><name sortKey="Mtapuri Zinyowera, S" uniqKey="Mtapuri Zinyowera S">S Mtapuri-Zinyowera</name></author><author><name sortKey="Mapingure, Mp" uniqKey="Mapingure M">MP Mapingure</name></author><author><name sortKey="Paul, Nh" uniqKey="Paul N">NH Paul</name></author><author><name sortKey="Sangweme, D" uniqKey="Sangweme D">D Sangweme</name></author><author><name sortKey="Hlerema, G" uniqKey="Hlerema G">G Hlerema</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Erhun, Wo" uniqKey="Erhun W">WO Erhun</name></author><author><name sortKey="Agbani, Eo" uniqKey="Agbani E">EO Agbani</name></author><author><name sortKey="Adesanya, So" uniqKey="Adesanya S">SO Adesanya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Loha, E" uniqKey="Loha E">E Loha</name></author><author><name sortKey="Tefera, K" uniqKey="Tefera K">K Tefera</name></author><author><name sortKey="Lindtj Rn, B" uniqKey="Lindtj Rn B">B Lindtjørn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deribew, A" uniqKey="Deribew A">A Deribew</name></author><author><name sortKey="Birhanu, Z" uniqKey="Birhanu Z">Z Birhanu</name></author><author><name sortKey="Sena, L" uniqKey="Sena L">L Sena</name></author><author><name sortKey="Dejene, T" uniqKey="Dejene T">T Dejene</name></author><author><name sortKey="Reda, Aa" uniqKey="Reda A">AA Reda</name></author><author><name sortKey="Sudhakar, M" uniqKey="Sudhakar M">M Sudhakar</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Konradsen, F" uniqKey="Konradsen F">F Konradsen</name></author><author><name sortKey="Amerasinghe, Fp" uniqKey="Amerasinghe F">FP Amerasinghe</name></author><author><name sortKey="Van Der Hoek, W" uniqKey="Van Der Hoek W">W van der Hoek</name></author><author><name sortKey="Amerasinghe, Ph" uniqKey="Amerasinghe P">PH Amerasinghe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silva, Kt" uniqKey="Silva K">KT Silva</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Spencer, S" uniqKey="Spencer S">S Spencer</name></author><author><name sortKey="Grant, Ad" uniqKey="Grant A">AD Grant</name></author><author><name sortKey="Piola, P" uniqKey="Piola P">P Piola</name></author><author><name sortKey="Tukpo, K" uniqKey="Tukpo K">K Tukpo</name></author><author><name sortKey="Okia, M" uniqKey="Okia M">M Okia</name></author><author><name sortKey="Gracia, M" uniqKey="Gracia M">M Gracia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tekelehaimanot, A" uniqKey="Tekelehaimanot A">A Tekelehaimanot</name></author><author><name sortKey="Sachs, Jd" uniqKey="Sachs J">JD Sachs</name></author><author><name sortKey="Curtis, C" uniqKey="Curtis C">C Curtis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Curtis, C" uniqKey="Curtis C">C Curtis</name></author><author><name sortKey="Maxwell, C" uniqKey="Maxwell C">C Maxwell</name></author><author><name sortKey="Leminge, M" uniqKey="Leminge M">M Leminge</name></author><author><name sortKey="Kilama, Wl" uniqKey="Kilama W">WL Kilama</name></author><author><name sortKey="Steketee, Rw" uniqKey="Steketee R">RW Steketee</name></author><author><name sortKey="Hawley, Wa" uniqKey="Hawley W">WA Hawley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Noor, Am" uniqKey="Noor A">AM Noor</name></author><author><name sortKey="Mutheu, Jj" uniqKey="Mutheu J">JJ Mutheu</name></author><author><name sortKey="Tatem, Aj" uniqKey="Tatem A">AJ Tatem</name></author><author><name sortKey="Hay, Si" uniqKey="Hay S">SI Hay</name></author><author><name sortKey="Snow, Rw" uniqKey="Snow R">RW Snow</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hill, J" uniqKey="Hill J">J Hill</name></author><author><name sortKey="Lines, J" uniqKey="Lines J">J Lines</name></author><author><name sortKey="Rowland, M" uniqKey="Rowland M">M Rowland</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Infect Ecol Epidemiol</journal-id><journal-id journal-id-type="iso-abbrev">Infect Ecol Epidemiol</journal-id><journal-id journal-id-type="publisher-id">IEE</journal-id><journal-title-group><journal-title>Infection Ecology & Epidemiology</journal-title></journal-title-group><issn pub-type="epub">2000-8686</issn><publisher><publisher-name>Co-Action Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27141987</article-id><article-id pub-id-type="pmc">4854845</article-id><article-id pub-id-type="publisher-id">30822</article-id><article-id pub-id-type="doi">10.3402/iee.v6.30822</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>A systematic review of knowledge, attitudes and beliefs about malaria among the South Asian population</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Regmi</surname><given-names>Krishna</given-names></name><degrees>MPH, PhD</degrees><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Kunwar</surname><given-names>Anju</given-names></name><degrees>BSc, MSc</degrees><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Ortega</surname><given-names>Leonard</given-names></name><degrees>MD, MSc</degrees><xref ref-type="aff" rid="AF0002">2</xref></contrib></contrib-group><aff id="AF0001"><label>1</label>Faculty of Health and Social Sciences, Institute for Health Research, University of Bedfordshire, Luton, UK</aff><aff id="AF0002"><label>2</label>Global Malaria Programme, World Health Organization, Geneva, Switzerland</aff><author-notes><corresp id="cor1"><label>*</label>Correspondence to: Krishna Regmi, Faculty of Health and Social Sciences, Institute for Health Research, University of Bedfordshire, Luton, LU2 8LE, UK, Email: <email xlink:href="Krishna.Regmi@beds.ac.uk">Krishna.Regmi@beds.ac.uk</email></corresp><fn><p>Responsible Editor: Sven Bergström, Umeå University, Sweden.</p></fn></author-notes><pub-date pub-type="epub"><day>02</day><month>5</month><year>2016</year></pub-date><pub-date pub-type="collection"><year>2016</year></pub-date><volume>6</volume><elocation-id content-type="doi">10.3402/iee.v6.30822</elocation-id><history><date date-type="received"><day>24</day><month>12</month><year>2015</year></date><date date-type="rev-recd"><day>02</day><month>4</month><year>2016</year></date><date date-type="accepted"><day>06</day><month>4</month><year>2016</year></date></history><permissions><copyright-statement>© 2016 Krishna Regmi et al.</copyright-statement><copyright-year>2016</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/4.0/"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><sec id="st1"><title>Background</title><p>Malaria is one of the deadliest mosquito-borne diseases in the world. More than 80% of the total populations are at risk of malaria in the 22 countries in Asia and the Pacific. South Asia alone is home to an estimated 1.4 billion people at risk of contracting malaria. Despite the remarkable progress in reducing the burden of malaria, evidence of the disease based on knowledge of the social and cultural contexts from a South Asian perspective is limited. Our objective was to understand the knowledge, attitudes and beliefs about malaria in South Asian communities.</p></sec><sec id="st2"><title>Methodology</title><p>We conducted a systematic literature review, searching six databases, between 1990 and 2015, focusing on knowledge, attitudes and beliefs about malaria in South Asia. Databases were searched using both ‘free terms’ and ‘index terms’ funnelled using Boolean operators and truncations. Inclusion and exclusion criteria were set, and included papers were scrutinised, employing a critical appraisal tool to find the best available evidences to support the study purpose.</p></sec><sec id="st3"><title>Results and discussion</title><p>Evidence from 32 articles (26 quantitative, four qualitative and two mixed methods). General knowledge and awareness of the disease, its transmission, and control and preventative measures were generally found to be lacking amongst both the general public and healthcare professionals. In addition, the study shows that poor socio-economic factors – including limited access to services due to poor/limited availability – and issues of affordability are considered as major risk factors.</p></sec><sec id="st4"><title>Conclusion</title><p>This review suggests the importance of increasing health awareness, mobilising the local or community healthcare professionals, for prevention as well as early detection and effective treatment of malaria among people who are at risk. Malaria is also a disease associated with poverty and socio-cultural factors; therefore, strong political will, wider partnerships between health and non-health sectors, and strengthening health systems’ technical and managerial capabilities at all level of primary healthcare systems, is inevitable.</p></sec></abstract><kwd-group><kwd>malaria</kwd><kwd>South Asia</kwd><kwd>primary healthcare</kwd><kwd>eradicating malaria</kwd><kwd>control and prevention</kwd><kwd>systematic review</kwd></kwd-group></article-meta></front><body><p>Malaria is a public health problem as it kills more than 600,000 people every year. Over half of the population is known to be at risk of malaria globally, and most of them are children of under-five (<xref rid="CIT0001" ref-type="bibr">1</xref>). Malaria is an acute febrile illness caused by the parasites of the genus <italic>Plasmodium</italic>, of which there are four species (<italic>P. vivax</italic>, <italic>P. ovale</italic>, <italic>P. malariae</italic> and <italic>P. falciparum</italic>) that infect humans, of which <italic>P. falciparum</italic> can be fatal if not treated immediately, and mixed species infections are common in endemic areas (<xref rid="CIT0002" ref-type="bibr">2</xref>). Recently, Heymann (<xref rid="CIT0003" ref-type="bibr">3</xref>) discussed that globally <italic>P. vivax</italic> and <italic>P. falciparum</italic> are the most common species, and <italic>P. falciparum</italic> is considered a serious public health threat because of its severity and often fatal outcome.</p><p>Africa accounts for 90% of the mortality burden of malaria, and South East Asia accounts for 10% of the burden (<xref rid="CIT0002" ref-type="bibr">2</xref>, <xref rid="CIT0004" ref-type="bibr">4</xref>). World Health Organization (WHO) reports that in the Asia and Pacific region, which covers 22 countries, about 2.1 billion people (80% of the total population) are at risk of getting malaria. In this area, four countries – Afghanistan, Bangladesh, India and Pakistan have 1,000 or more cases per 100,000 population (<xref rid="CIT0005" ref-type="bibr">5</xref>). As of writing this article, there was no aggregated data available for the cases of malaria in South Asia. This region covers eight countries India, Pakistan, Bhutan, Bangladesh, Sri Lanka, Nepal, Maldives and Afghanistan – which is also the scope of the article. Based on data extracted from each country from the World Health Report published in 2015 (<xref rid="CIT0002" ref-type="bibr">2</xref>), this region alone has a reported point estimate of 19.5 million (19,464,050) malaria cases and 29 thousand (28,830) deaths, with 1.4 billion total population at risk (<xref ref-type="table" rid="T0001">Table 1</xref>). Children below the age of five are most vulnerable, with approximately 86% of deaths from malaria being in this age group (<xref rid="CIT0006" ref-type="bibr">6</xref>). Pregnant women were the second most vulnerable group due to anaemia, reduced immunity and increased vulnerability to infection and illness (<xref rid="CIT0007" ref-type="bibr">7</xref>). At-risk categories include indigenous people, forest-related workers and settlers, subsistence farmers and migrant labourers working in mines, plantations, road construction, dams and irrigation.</p><table-wrap id="T0001" position="float"><label>Table 1</label><caption><p>Malaria in South Asia</p></caption><table frame="hsides" rules="groups"><thead><tr><th valign="bottom" align="left" rowspan="1" colspan="1">Country</th><th valign="bottom" align="center" rowspan="1" colspan="1">Population</th><th valign="bottom" align="center" rowspan="1" colspan="1">Population at risk</th><th valign="bottom" align="center" rowspan="1" colspan="1">Reported cases (positive)</th><th valign="bottom" align="center" rowspan="1" colspan="1">Reported deaths</th><th valign="bottom" align="center" rowspan="1" colspan="1">Estimated cases</th><th valign="bottom" align="center" rowspan="1" colspan="1">Estimated deaths</th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">India</td><td align="center" rowspan="1" colspan="1">1,295,300,000</td><td align="center" rowspan="1" colspan="1">1,178,700,000</td><td align="center" rowspan="1" colspan="1">1,102,205</td><td align="center" rowspan="1" colspan="1">561</td><td align="center" rowspan="1" colspan="1">17,000,000</td><td align="center" rowspan="1" colspan="1">26,000</td></tr><tr><td align="left" rowspan="1" colspan="1">Pakistan</td><td align="center" rowspan="1" colspan="1">185,044,286</td><td align="center" rowspan="1" colspan="1">181,918,666</td><td align="center" rowspan="1" colspan="1">275,149</td><td align="center" rowspan="1" colspan="1">56</td><td align="center" rowspan="1" colspan="1">1,500,000</td><td align="center" rowspan="1" colspan="1">1,100</td></tr><tr><td align="left" rowspan="1" colspan="1">Bangladesh</td><td align="center" rowspan="1" colspan="1">159,077,513</td><td align="center" rowspan="1" colspan="1">16,480,430</td><td align="center" rowspan="1" colspan="1">10,216</td><td align="center" rowspan="1" colspan="1">45</td><td align="center" rowspan="1" colspan="1">700,000</td><td align="center" rowspan="1" colspan="1">1,600</td></tr><tr><td align="left" rowspan="1" colspan="1">Bhutan</td><td align="center" rowspan="1" colspan="1">765,008</td><td align="center" rowspan="1" colspan="1">121,441</td><td align="center" rowspan="1" colspan="1">48</td><td align="center" rowspan="1" colspan="1">0</td><td align="center" rowspan="1" colspan="1">50</td><td align="center" rowspan="1" colspan="1">–</td></tr><tr><td align="left" rowspan="1" colspan="1">Nepal</td><td align="center" rowspan="1" colspan="1">28,174,724</td><td align="center" rowspan="1" colspan="1">13,509,780</td><td align="center" rowspan="1" colspan="1">1,469</td><td align="center" rowspan="1" colspan="1">0</td><td align="center" rowspan="1" colspan="1">14,000</td><td align="center" rowspan="1" colspan="1">10</td></tr><tr><td align="left" rowspan="1" colspan="1">Sri Lanka</td><td align="center" rowspan="1" colspan="1">20,618,991</td><td align="center" rowspan="1" colspan="1">N/A</td><td align="center" rowspan="1" colspan="1">49</td><td align="center" rowspan="1" colspan="1">0</td><td align="center" rowspan="1" colspan="1">–</td><td align="center" rowspan="1" colspan="1">–</td></tr><tr><td align="left" rowspan="1" colspan="1">Maldives</td><td align="center" rowspan="1" colspan="1">–</td><td align="center" rowspan="1" colspan="1">–</td><td align="center" rowspan="1" colspan="1">0</td><td align="center" rowspan="1" colspan="1">0</td><td align="center" rowspan="1" colspan="1">–</td><td align="center" rowspan="1" colspan="1">–</td></tr><tr><td align="left" rowspan="1" colspan="1">Afghanistan</td><td align="center" rowspan="1" colspan="1">31,627,506</td><td align="center" rowspan="1" colspan="1">23,902,611</td><td align="center" rowspan="1" colspan="1">61,362</td><td align="center" rowspan="1" colspan="1">32</td><td align="center" rowspan="1" colspan="1">250,000</td><td align="center" rowspan="1" colspan="1">120</td></tr><tr><td align="left" rowspan="1" colspan="1"></td><td align="center" rowspan="1" colspan="1">1,720,608,028</td><td align="center" rowspan="1" colspan="1">1,414,632,928</td><td align="center" rowspan="1" colspan="1">1,450,498</td><td align="center" rowspan="1" colspan="1">694</td><td align="center" rowspan="1" colspan="1">19,464,050</td><td align="center" rowspan="1" colspan="1">28,830</td></tr></tbody></table><table-wrap-foot><fn><p>WHO (<xref rid="CIT0002" ref-type="bibr">2</xref>).</p></fn></table-wrap-foot></table-wrap><p>It is important to highlight Bhutan, a country which is in the elimination phase; the population living in active foci is the population at risk. There were no malaria deaths. Nepal has a current estimated malaria death rate of less than 10. Similarly, Sri Lanka has had no local transmission since October 2012; only cases imported from other countries were detected (<xref rid="CIT0002" ref-type="bibr">2</xref>). Thus, there is no population at risk. Even though the number of confirmed malaria cases in the South East Asia region, including those in South Asia (SA), has generally decreased from 2.9 million in 2000 to 2 million in 2012, the disease still remains a significant threat to peoples’ lives and livelihoods (<xref rid="CIT0008" ref-type="bibr">8</xref>).</p><p>WHO (<xref rid="CIT0002" ref-type="bibr">2</xref>) recommends that every suspected case of malaria should receive a diagnostic test (<xref rid="CIT0002" ref-type="bibr">2</xref>). There are several tests available (microscopy, serology, polymerase chain reaction (PCR)-based assay and lateral flow immunochromatographic antigen detection assays), with antigen detection assays being commonly known as ‘malaria rapid diagnostic tests’ (RDTs). This test is reliable and is often recommended to detect malaria parasites in the human body if microscopy is not available or not reliable (<xref rid="CIT0003" ref-type="bibr">3</xref>).</p><p>Evidence suggests that key approaches to preventing malaria include regular use of long-lasting insecticidal nets, indoor spraying of homes with residual insecticides and treatment (<xref rid="CIT0002" ref-type="bibr">2</xref>). Chloroquine is one popular drug and is still effective on <italic>P. vivax</italic>, but <italic>P. falciparum</italic> is resistant to it in many parts of the world. Artemisinin-based combination therapy (ACT) is considered as highly effective, not only as treatment for uncomplicated <italic>P. falciparum</italic> malaria, but also to help delay development of resistance (<xref rid="CIT0003" ref-type="bibr">3</xref>).</p><p>SA had an estimate of reducing malaria cases and deaths by 75% by 2015 (from the year 2000) with a long-term goal of eliminating the disease, but this target is still far from being reached (<xref rid="CIT0009" ref-type="bibr">9</xref>). Kumar et al. (<xref rid="CIT0010" ref-type="bibr">10</xref>) argue that the ‘global malaria situation is increasingly being challenged owing to lack of credible malaria vaccine and the emergence of drug resistance to most of the available antimalarials’ (p. 2116).</p><p>There is a substantial body of literature in existence concerning malaria, but this evidence is often scattered and limited to establishing knowledge about malaria from the perspectives of vectors and environmental, economic, social and health-service features in SA communities (<xref rid="CIT0011" ref-type="bibr">11</xref>–<xref rid="CIT0014" ref-type="bibr">14</xref>). Similarly, several pieces of evidence suggest there is a gap between knowledge and understanding of the disease and its control and the implementation of that knowledge, largely due to socio-economic factors (the knowledge–implementation gap) (<xref rid="CIT0015" ref-type="bibr">15</xref>–<xref rid="CIT0017" ref-type="bibr">17</xref>). As Dash et al. (<xref rid="CIT0018" ref-type="bibr">18</xref>) reported, people's understanding of malaria, its transmission, treatment and prevention is generally low and the neglect of SA, especially highly populated and malaria-endemic countries like India, would bring substantial challenges to the global reduction of malaria-related mortality and morbidity.</p><p>A comprehensive understanding of malaria exposure due to behavioural and social factors and gaps in knowledge would not only contribute to a better understanding of unexpected disease outbreaks and unpredicted disease presentations, but is also essential in developing and reflecting appropriate policies and guidelines into practice in line with malaria control and prevention (<xref rid="CIT0011" ref-type="bibr">11</xref>). Therefore, it was justified and timely to conduct a systematic review of knowledge, attitudes and beliefs about malaria to support and inform further development of appropriate prevention and control interventions that may contribute to eradicate malaria transmission in SA.</p><sec id="S0002"><title>Methodology</title><p>We conducted a systematic review of published literature, focusing on knowledge, attitudes and beliefs about malaria among the population of SA. Boland et al. (<xref rid="CIT0019" ref-type="bibr">19</xref>) argue that a systematic review is considered as a gold standard method since it is ‘synthesising the findings of several studies investigating the same questions’ (p. 3) to provide high-quality evidence to inform healthcare policy on decision-making in practice (<xref rid="CIT0020" ref-type="bibr">20</xref>, <xref rid="CIT0021" ref-type="bibr">21</xref>). In addition, a systematic review has a propensity to be more transparent when the selection of the studies for review is made carefully (<xref rid="CIT0022" ref-type="bibr">22</xref>). Nevertheless, the Institute of Medicine (<xref rid="CIT0023" ref-type="bibr">23</xref>) warns that systematic reviews might equally ‘fail to acknowledge or address the risk of reporting biases, neglect to appraise the quality of individual studies included in the review, and (they) are subject to errors during the data extraction and analysis’ (p. 82).</p><sec id="S0002-S20001"><title>Search strategy</title><p>A search strategy was developed by the research team, led by one of the lead authors (KR). Through identifying and examining primary researches in the topic area, six major electronic databases – MEDLINE, Global Health, PsycINFO, CINAHL, EMBASE and AMED – were searched using both ‘free terms’ and ‘index terms’, focusing on the studies related to malaria – knowledge, attitudes and beliefs amongst South Asian communities. Additional grey literatures – OpenGrey, Ethos and British Library Catalogue – were also searched. Following the formulation of research questions, inclusion and exclusion criteria were set. The search strategy to address this question involved searching these electronic databases in four groups (<xref ref-type="table" rid="T0002">Table 2</xref>).</p><table-wrap id="T0002" position="float"><label>Table 2</label><caption><p>Word groups used to identify relevant articles</p></caption><table frame="hsides" rules="groups"><thead><tr><th valign="bottom" align="left" rowspan="1" colspan="1">Word group 1 – Population</th><th valign="bottom" align="center" rowspan="1" colspan="1">Word group 2 – Intervention</th><th valign="bottom" align="center" rowspan="1" colspan="1">Word group 3 – Disease or conditions, context or setting</th><th valign="bottom" align="center" rowspan="1" colspan="1">Word group 4 – Outcomes</th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">‘Male’ OR<break></break>‘Female’ OR ‘Adult’ OR ‘Child*’ OR ‘Elderly’</td><td align="left" rowspan="1" colspan="1">‘Insecticide treated bed net’ OR ‘ITNs’ OR ‘LLIN’ OR ‘bed net’ OR<break></break>‘Indoor Residual Spray’ OR ‘IRS’ OR ‘Intermittent’ OR ‘Prevent*’ OR ‘Treat*’<break></break>OR ‘Artemisinin-based Combination Theory’ OR ‘ACT’ OR ‘community education’ or ‘health promotion’ OR ‘public health’ OR ‘primary care’ OR ‘prevent*’ OR ‘control*’ OR ‘Preventative care’</td><td align="left" rowspan="1" colspan="1">‘Malaria’ OR ‘mosquito’ OR ‘febrile patients’ OR ‘South Asia[*1]’ OR
‘SAARC’ OR ‘Afghanistan’ OR ‘Afghanistan[*1]’ OR ‘Bhutan’ OR ‘Bhutan[*3]’ OR ‘Nepal’ OR ‘Nepal[*3]’ OR ‘India’ OR ‘India[*1]’ OR ‘Pakistan’ OR ‘Pakistan[*1]’ OR ‘Bangladesh’ OR ‘Maldives’ OR ‘Sri Lanka’ OR ‘Sri Lanka[*1]’</td><td align="left" rowspan="1" colspan="1">‘Improv*’ OR<break></break>‘improvement’ OR ‘access*’ OR ‘utilization’ OR ‘utilization’ OR ‘utilis*’ OR ‘utilize*’ OR ‘aware’ OR ‘prevent*’ OR ‘control*’ OR ‘mortality and morbidity’ OR ‘quality of life’<break></break>‘Health need’ OR<break></break>‘outcome’ OR<break></break>‘results’ OR<break></break>‘quality’ OR ‘impact’ OR ‘effective’ OR ‘change’ ‘Knowledge’ OR ‘awareness’ OR ‘attitude’ OR ‘beliefs’ OR ‘behavior’ ‘community knowledge’ OR ‘community response’</td></tr><tr><td colspan="4" align="left" rowspan="1">Inclusion criteria (limit):
<list list-type="bullet"><list-item><p><italic>Population</italic>: human</p></list-item><list-item><p><italic>Publication date</italic>: 1990–2015</p></list-item><list-item><p><italic>Document/record type</italic>: peer-review article</p></list-item><list-item><p><italic>Issues or attributes</italic>: studies focusing on knowledge, attitudes and belief associated with the prevention and control measures of malaria</p></list-item><list-item><p><italic>Location:</italic> South Asia (India, Pakistan, Bhutan, Bangladesh, Sri Lanka, Nepal, Maldives and Afghanistan)</p></list-item><list-item><p><italic>Language</italic>: English</p></list-item></list></td></tr></tbody></table><table-wrap-foot><fn><p>All groups are combined using Boolean operators.</p></fn></table-wrap-foot></table-wrap></sec><sec id="S0002-S20002"><title>Screening strategy</title><p>Screening was undertaken in two phases in this review. Firstly, the titles and abstracts of the retrieved literature were reviewed by the two authors in order to identify if the literature met the set inclusion criteria. During this process, some studies were excluded due to the fact that they did not meet the set inclusion criteria. Secondly, the full texts of the selected articles were retrieved, more articles were excluded and the studies that passed the screening criteria were included in the study. Manual screening of the articles was also considered through the references list for further articles relevant to the study. The PRISMA flow diagram was followed in a stepwise process, and the final 33 articles were screened and identified for the review (<xref ref-type="fig" rid="F0001">Fig. 1</xref>).</p><fig id="F0001" position="float"><label>Fig. 1</label><caption><p>PRISMA flow diagram.</p></caption><graphic xlink:href="IEE-6-30822-g001"></graphic></fig></sec></sec><sec sec-type="results" id="S0003"><title>Results</title><p>In this study, 1,660 studies were identified from the initial search of the chosen six major databases, with an additional 27 studies being identified as relevant to the topic area through hand-searching in other sources, which made a total of 1,687. Articles from both types of searching were screened and 1,641 studies were retrieved after 46 duplicates were removed. Of the 1,641 articles, 1,432 articles were excluded based on title and abstract not being relevant to the research question, the study being carried out outside South Asia and some articles not being in academic journals. Therefore, 209 articles were selected and the full texts of those articles were retrieved. All articles were examined based on set inclusion and exclusion criteria, and finally, 93 articles were found to be eligible. A further 61 articles were excluded since the backgrounds and discussions of some articles were not relevant to the study, some articles were not peer-reviewed, and further duplicates were removed. Overall, 32 publications were included in this study. The primary evidence base is comprised of quantitative (<italic>n</italic>=26) followed by qualitative (<italic>n</italic>=4) and mixed methods (<italic>n</italic>=2). Most of the studies were conducted in India (<italic>n</italic>=19) followed by Bangladesh (<italic>n</italic>=4), Sri Lanka (<italic>n</italic>=3), Pakistan (<italic>n</italic>=2), Bhutan (<italic>n</italic>=2), Afghanistan (<italic>n</italic>=1) and Nepal (<italic>n</italic>=1). Although all studies were published after 1990, the study periods ranged from 2000 to 2012 with a total sample size of 42,393 (ranging from 73 to 7,117). It is noted that one study did not provide sample size, and two studies did not report study periods (<xref ref-type="table" rid="T0003">Table 3</xref>).</p><table-wrap id="T0003" position="float"><label>Table 3</label><caption><p>Summary of the articles included</p></caption><table frame="hsides" rules="groups"><thead><tr><th valign="bottom" align="left" rowspan="1" colspan="1"></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th><th valign="bottom" align="center" colspan="2" rowspan="1">Quality appraisal
[from Smith et al., 2009 (<xref rid="CIT0024" ref-type="bibr">24</xref>)]</th><th valign="bottom" align="center" rowspan="1" colspan="1"></th></tr><tr><th valign="bottom" align="left" rowspan="1" colspan="1"></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th><th valign="bottom" colspan="2" rowspan="1"><hr></hr></th><th valign="bottom" align="center" rowspan="1" colspan="1"></th></tr><tr><th valign="bottom" align="left" rowspan="1" colspan="1">First author (year)</th><th valign="bottom" align="center" rowspan="1" colspan="1">Title and journal (impact factor)</th><th valign="bottom" align="center" rowspan="1" colspan="1">Country</th><th valign="bottom" align="center" rowspan="1" colspan="1">Study design (study period)</th><th valign="bottom" align="center" rowspan="1" colspan="1">Population group/sample size</th><th valign="bottom" align="center" rowspan="1" colspan="1">Qualitative</th><th valign="bottom" align="center" rowspan="1" colspan="1">Quantitative</th><th valign="bottom" align="center" rowspan="1" colspan="1">Overall quality rating<xref ref-type="table-fn" rid="TF0001">*</xref></th></tr></thead><tbody><tr><td align="left" rowspan="1" colspan="1">Ahmed et al. 2009 (<xref rid="CIT0025" ref-type="bibr">25</xref>)
</td><td align="left" rowspan="1" colspan="1">Knowledge on the transmission, prevention and treatment of malaria among two endemic populations of Bangladesh and their health- seeking behavior. Malar J [IF: 3.11]</td><td align="left" rowspan="1" colspan="1">Bangladesh</td><td align="left" rowspan="1" colspan="1">Survey, semi-structured questionnaire/face-to-face interview<break></break>(July–November 2007)</td><td align="left" rowspan="1" colspan="1">General population (9,750)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,7,10</td><td align="left" rowspan="1" colspan="1">weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Ahmed et al. 2014 (<xref rid="CIT0026" ref-type="bibr">26</xref>)
</td><td align="left" rowspan="1" colspan="1">Conventional or interpersonal communication: which works best in disseminating malaria information in an endemic rural Bangladeshi community? PloS One [IF 3.23]</td><td align="left" rowspan="1" colspan="1">Bangladesh</td><td align="left" rowspan="1" colspan="1">Cross-sectional survey, pretested,<break></break>semi-structured questionnaire (July–November 2007 & January–February 2012)</td><td align="left" rowspan="1" colspan="1">General population (750 households)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,6,7,9,10</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Ahmed et al. 2011 (<xref rid="CIT0027" ref-type="bibr">27</xref>)
</td><td align="left" rowspan="1" colspan="1">Free distribution of insecticidal bed nets improves possession and preferential use by households and is equitable: findings from two cross-sectional surveys in 13 malaria endemic districts of Bangladesh. Malar J [IF: 3.11]</td><td align="left" rowspan="1" colspan="1">Bangladesh</td><td align="left" rowspan="1" colspan="1">Cross-sectional surveys, structured interviews<break></break>(2008 and 2011)</td><td align="left" rowspan="1" colspan="1">General population (3,760 in 2008 and 7,895 in 2011)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,3,4,5,6,7,9,10</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Anand et al. 2014 (<xref rid="CIT0028" ref-type="bibr">28</xref>)
</td><td align="left" rowspan="1" colspan="1">Knowledge and use of personal protective measures against mosquito borne diseases in a resettlement colony of Delhi. Ann Med Health Sci Res [IF: 0.00]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Cross-sectional study, pre-tested, pre-designed, semi-structured questionnaire<break></break>(June 2011–July 2011)</td><td align="left" rowspan="1" colspan="1">General population (100)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,7,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Bashar et al. 2012 (<xref rid="CIT0029" ref-type="bibr">29</xref>)
</td><td align="left" rowspan="1" colspan="1">Socio-demographic factors influencing knowledge, attitude and practice (KAP) regarding malaria in Bangladesh. BMC Public Health [IF: 2.264]</td><td align="left" rowspan="1" colspan="1">Bangladesh</td><td align="left" rowspan="1" colspan="1">Survey, structured questionnaires and the interviews, (July–October 2011)</td><td align="left" rowspan="1" colspan="1">General population (468)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,7,10</td><td align="left" rowspan="1" colspan="1">Weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Chourasia et al. 2014 (<xref rid="CIT0030" ref-type="bibr">30</xref>)
</td><td align="left" rowspan="1" colspan="1">Household training vs. mass campaigns: a better method of health communication for preventing malaria. Trop Doct [IF: 0.48)</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Interviewer-administered structured questionnaire (September–December 2012)</td><td align="left" rowspan="1" colspan="1">General population (218)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,7,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Dambhare et al. 2012 (<xref rid="CIT0031" ref-type="bibr">31</xref>)
</td><td align="left" rowspan="1" colspan="1">Knowledge, attitude and practice of malaria transmission and its prevention among the school going adolescents in Wardha District, Central India. Glob J Health Sci [IF: 0.00]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Cross sectional study, pre-designed, pre-tested questionnaire<break></break>(October–December 2010)</td><td align="left" rowspan="1" colspan="1">School going adolescents (1,096)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,6,7,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Das and Ravindran 2010 (<xref rid="CIT0032" ref-type="bibr">32</xref>)
</td><td align="left" rowspan="1" colspan="1">Factors affecting treatment-seeking for febrile illness in a malaria endemic block in Boudh district, Orissa, India: policy implications for malaria control. Malar J [IF: 3.11]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Cross-sectional community-based survey, using structured interviews<break></break>(2006)</td><td align="left" rowspan="1" colspan="1">General population (323) [300-service users and 23 – service providers]</td><td align="center" rowspan="1" colspan="1">1,2,3,4,5,7,8,9,10</td><td align="left" rowspan="1" colspan="1">1,2,7,8,9,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Das and Ravindran 2011 (<xref rid="CIT0033" ref-type="bibr">33</xref>)
</td><td align="left" rowspan="1" colspan="1">Community knowledge on malaria among febrile patients in an endemic district of Orissa, India. J Vector Borne Dis [IF: 0.806]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Cross-sectional community-based survey, structured interviews<break></break>(June–August 2006)</td><td align="left" rowspan="1" colspan="1">General population (300)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,7,9,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Dhawan et al. 2014 (<xref rid="CIT0034" ref-type="bibr">34</xref>)
</td><td align="left" rowspan="1" colspan="1">Malaria-related knowledge and prevention practices in four neighborhoods in and around Mumbai: a cross sectional study. Malar J [IF: 3.11]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Quantitative – cross-sectional, structured interviewers-administered questionnaire<break></break>(December 2010–January 2011)</td><td align="left" rowspan="1" colspan="1">General population (119)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,4,7,10</td><td align="left" rowspan="1" colspan="1">Weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Fernando et al. 2008 (<xref rid="CIT0035" ref-type="bibr">35</xref>)
</td><td align="left" rowspan="1" colspan="1">Community factors affecting long-lasting impregnated mosquito net use for malaria control in Sri Lanka. Trans R Soc Trop Med Hyg [IF: 1.931]</td><td align="left" rowspan="1" colspan="1">Sri Lanka</td><td align="left" rowspan="1" colspan="1">Community-based cross-sectional survey among<break></break>(June–July 2007)</td><td align="left" rowspan="1" colspan="1">General population (2,467)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,7,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Howard et al. 2010 (<xref rid="CIT0036" ref-type="bibr">36</xref>)
</td><td align="left" rowspan="1" colspan="1">Malaria control under the Taliban regime: insecticide-treated net purchasing, coverage, and usage among men and women in eastern Afghanistan. Mala J[IF: 3.11]</td><td align="left" rowspan="1" colspan="1">Afghanistan</td><td align="left" rowspan="1" colspan="1">Mixed methods – focus group discussions, in-depth and quantitative household survey<break></break>(February–September 2000)</td><td align="left" rowspan="1" colspan="1">General population (566) [Fifteen focus group discussions (82+40) and 30 in-depth interviews, 414 households]</td><td align="center" rowspan="1" colspan="1">1,2,3,4,5,6,7,8,9,10</td><td align="left" rowspan="1" colspan="1">1,2,4,5,7,9,10</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Hussain et al. 2013 (<xref rid="CIT0037" ref-type="bibr">37</xref>)
</td><td align="left" rowspan="1" colspan="1">Public health system readiness to treat malaria in Odisha State of India. Malar J [IF: 3.11]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Cross-sectional study, key informant interviews, semi-structured interviews and health facility assessments (February–July 2012)</td><td align="left" rowspan="1" colspan="1">Auxiliary nurse midwives and accredited social health activists (455)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,7,10</td><td align="left" rowspan="1" colspan="1">Weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Joshi and Banjara 2008 (<xref rid="CIT0038" ref-type="bibr">38</xref>)
</td><td align="left" rowspan="1" colspan="1">Malaria related knowledge, practices and behaviour of people in Nepal. J Vector Borne Dis [IF: 0.806]</td><td align="left" rowspan="1" colspan="1">Nepal</td><td align="left" rowspan="1" colspan="1">Cross-sectional study using structured questionnaire and focus group discussions (December 2004–April 2005)</td><td align="left" rowspan="1" colspan="1">General population (1,330)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,7,10</td><td align="left" rowspan="1" colspan="1">Weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Kirkby et al. 2013 (<xref rid="CIT0039" ref-type="bibr">39</xref>)
</td><td align="left" rowspan="1" colspan="1">Knowledge, attitudes and practices relevant to malaria elimination amongst resettled populations in a post-conflict district of northern Sri Lanka. Trans R Soc Trop Med Hyg [IF: 1.931]</td><td align="left" rowspan="1" colspan="1">Sri Lanka</td><td align="left" rowspan="1" colspan="1">Descriptive cross-sectional, structured questionnaire. Questionnaire (2011)</td><td align="left" rowspan="1" colspan="1">General population (300)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,6,7,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Kumar et al. 2014 (<xref rid="CIT0040" ref-type="bibr">40</xref>)
</td><td align="left" rowspan="1" colspan="1">Spatial trend, environmental and socioeconomic factors associated with malaria prevalence in Chennai. Malar J [IF: 3.11]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Questionnaire, field survey (2005–2011)</td><td align="left" rowspan="1" colspan="1">Not provided</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,7,10</td><td align="left" rowspan="1" colspan="1">Weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Lwin et al. 2014 (<xref rid="CIT0041" ref-type="bibr">41</xref>)
</td><td align="left" rowspan="1" colspan="1">‘It's effective but should I bother?’ A study of personal protection measures against Malaria in urban India. Public Health [IF: 1.434]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Quantitative – survey, interview questionnaire<break></break>(March–June, 2012)</td><td align="left" rowspan="1" colspan="1">General population (1,000)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,7,10</td><td align="left" rowspan="1" colspan="1">Weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Nandwani et al. 2014 (<xref rid="CIT0042" ref-type="bibr">42</xref>)
</td><td align="left" rowspan="1" colspan="1">Clinical profile of severe malaria: study from a tertiary care center in north India. J Parasit Dis [IF: 0.00]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Retrospective observational study<break></break>(August 2010 to October 2010)</td><td align="left" rowspan="1" colspan="1">Patients (160)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,7,10</td><td align="left" rowspan="1" colspan="1">Weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Pandit et al. 2010 (<xref rid="CIT0043" ref-type="bibr">43</xref>)
</td><td align="left" rowspan="1" colspan="1">Awareness and practice about preventive method against mosquito bite in Gujarat. Healthline [IF: 0.00].</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Quantitative – cross-sectional, questionnaire (June 2009)</td><td align="left" rowspan="1" colspan="1">General population (311)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,7,10</td><td align="left" rowspan="1" colspan="1">weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Qayum et al. 2012 (<xref rid="CIT0044" ref-type="bibr">44</xref>)
</td><td align="left" rowspan="1" colspan="1">SPHERE-based assessment of knowledge and preventive measures related to malaria among the displaced population of Jalozai, Pakistan. J Pak Med Assoc [IF 0.414]</td><td align="left" rowspan="1" colspan="1">Pakistan</td><td align="left" rowspan="1" colspan="1">Descriptive cross-sectional, structured questionnaire<break></break>(March–November 2010)</td><td align="left" rowspan="1" colspan="1">General population (116)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,7,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Sabin et al. 2010 (<xref rid="CIT0045" ref-type="bibr">45</xref>)
</td><td align="left" rowspan="1" colspan="1">Attitudes, knowledge, and practices regarding malaria prevention and treatment among pregnant women in Eastern India. Am J Trop Med Hyg [IF: 2.699]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Qualitative using in-depth interviews and focus group discussions<break></break>(April–May 2007)</td><td align="left" rowspan="1" colspan="1">Pregnant women (73) [32 in-depth interviews and six focus group discussions]</td><td align="center" rowspan="1" colspan="1">1,2,3,4,5,6,7,8,9,10</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Saha et al. 2015 (<xref rid="CIT0046" ref-type="bibr">46</xref>)
</td><td align="left" rowspan="1" colspan="1">Establishing communication mechanism for malaria prevention in Baiga tribal villages in Baiga chak area of Dindori district, Madhya Pradesh. Indian J Med Res [IF: 1.4]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Quasi experimental design using questions<break></break>(November 2011–February 2012)</td><td align="left" rowspan="1" colspan="1">General population (2,350)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,3,4,5,6,7,9,10</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Sarkar et al. 2009 (<xref rid="CIT0047" ref-type="bibr">47</xref>)
</td><td align="left" rowspan="1" colspan="1">Risk factors for malaria deaths in Jalpaiguri district, West Bengal, India: evidence for further action. Malar J [IF: 3.11]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Quantitative – using pre-tested structured questionnaire (2007–2008)</td><td align="left" rowspan="1" colspan="1">Total population (168)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,3,4,5,6,7,9,10</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Sharma et al. 2015 (<xref rid="CIT0048" ref-type="bibr">48</xref>)</td><td align="left" rowspan="1" colspan="1">Socio-economic & household risk factors of malaria in tribal areas of Madhya Pradesh, central India. Indian J Med Res [IF: 1.4]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Baseline survey using interviews (May 2005–June 2008)</td><td align="left" rowspan="1" colspan="1">General population (7,117)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,6,7,9,10</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Sood et al. 2010 (<xref rid="CIT0049" ref-type="bibr">49</xref>)
</td><td align="left" rowspan="1" colspan="1">Community awareness, perceptions, acceptability and preferences for using LLIN against malaria in villages of Uttar Pradesh, India. J Vector Borne Dis [IF: 0.806]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Community-based survey, structured questionnaire<break></break>(April–May 2009)</td><td align="left" rowspan="1" colspan="1">General population (596)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,7,10</td><td align="left" rowspan="1" colspan="1">weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Sundararajan et al. 2013 (<xref rid="CIT0050" ref-type="bibr">50</xref>)
</td><td align="left" rowspan="1" colspan="1">Barriers to malaria control among marginalized tribal communities: a qualitative study. PloS One [IF: 3.234]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Qualitative data using multiple<break></break>key informants and groups. (July 2012)</td><td align="left" rowspan="1" colspan="1">General population (84) [76-focus groups, and 8- individual interviews]</td><td align="center" rowspan="1" colspan="1">1,2,3,4,5,6,7,8,9,10</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Tobgay and Lhazeen 2010 (<xref rid="CIT0051" ref-type="bibr">51</xref>)
</td><td align="left" rowspan="1" colspan="1">Malaria perceptions and practices in Bhutan. Southeast Asian J Trop Med Public Health. [IF: 0.719].</td><td align="left" rowspan="1" colspan="1">Bhutan</td><td align="left" rowspan="1" colspan="1">Qualitative using focus group discussions and interviews<break></break>(July–August 2007)</td><td align="left" rowspan="1" colspan="1">Eight focus group discussions (<italic>n</italic>=80) [three with medical profession, three with<break></break>community members, and two with village<break></break>health workers]</td><td align="center" rowspan="1" colspan="1">1,2,3,4,6,7,8(partly),9,10</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Tobgay et al. 2013 (<xref rid="CIT0052" ref-type="bibr">52</xref>)
</td><td align="left" rowspan="1" colspan="1">Community-directed educational intervention for malaria elimination in Bhutan: quasi-experimental study in malaria endemic areas of Sarpang district. Malar J [IF: 3.11]</td><td align="left" rowspan="1" colspan="1">Bhutan</td><td align="left" rowspan="1" colspan="1">Quasi-experimental study, both qualitative and quantitative data collection methods (Study period – not provided)</td><td align="left" rowspan="1" colspan="1">General population (25+560) [13 in-depth interviews and 12 focus group discussions] & 560 households interviewed</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,3,4,5,6,7,9,10</td><td align="left" rowspan="1" colspan="1">Strong</td></tr><tr><td align="left" rowspan="1" colspan="1">Vijayakumar et al. 2009 (<xref rid="CIT0053" ref-type="bibr">53</xref>)
</td><td align="left" rowspan="1" colspan="1">Knowledge, attitude and practice on malaria: a study in a tribal belt of Orissa state, India with reference to use of long lasting treated mosquito nets. Acta Trop [IF: 2.519]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Mixed methods: quantitative (questionnaire) and qualitative (key informant interview and focus group discussions) (2002)</td><td align="left" rowspan="1" colspan="1">General population (656)</td><td align="center" rowspan="1" colspan="1">1,3,7</td><td align="left" rowspan="1" colspan="1">1,2,4,7,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Yadav et al. 2013 (<xref rid="CIT0054" ref-type="bibr">54</xref>)
</td><td align="left" rowspan="1" colspan="1">Knowledge, treatment-seeking behaviour and socio-economic impact of malaria in the desert of Rajasthan, India. South African India. South Afr J Epidemiol Infect [IF: 0.00]</td><td align="left" rowspan="1" colspan="1">India</td><td align="left" rowspan="1" colspan="1">Quantitative – cross-sectional, community-based study, questionnaire<break></break>(Study period: not provided)</td><td align="left" rowspan="1" colspan="1">General population (540)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">4,7,10</td><td align="left" rowspan="1" colspan="1">weak</td></tr><tr><td align="left" rowspan="1" colspan="1">Yasuoka et al. 2006 (<xref rid="CIT0055" ref-type="bibr">55</xref>)
</td><td align="left" rowspan="1" colspan="1">Impact of education on knowledge, agricultural practices, and community actions for mosquito control and mosquito-borne disease prevention in rice ecosystems in Sri Lanka. Am J Trop Med Hyg [IF: 2.7]</td><td align="left" rowspan="1" colspan="1">Sri Lanka</td><td align="left" rowspan="1" colspan="1">Cross-sectional, – two surveys before and after the intervention (2003)</td><td align="left" rowspan="1" colspan="1">General population (75 households)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,7,8,9,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr><tr><td align="left" rowspan="1" colspan="1">Zaidi et al. 2015 (<xref rid="CIT0056" ref-type="bibr">56</xref>)
</td><td align="left" rowspan="1" colspan="1">The quantitative evidence of malarial transmission and its associates in Bahawalpur, Pakistan. J Ayub Med Coll Abbottabad (IF: 0.00)</td><td align="left" rowspan="1" colspan="1">Pakistan</td><td align="left" rowspan="1" colspan="1">Cross-sectional, semi-structured questionnaires (January–June, 2008)</td><td align="left" rowspan="1" colspan="1">General population (1,623)</td><td align="center" rowspan="1" colspan="1">NA</td><td align="left" rowspan="1" colspan="1">1,2,4,5,7,10</td><td align="left" rowspan="1" colspan="1">Moderate</td></tr></tbody></table><table-wrap-foot><fn id="TF0001"><label>*</label><p>(i) Some studies did not report sufficient details about the quality, so missing quality appraisal criteria/question(s) mean not particular appraisal question(s) applicable or not reported. (ii) Overall quality rating scale: strong (9–10 criteria/questions of yes); moderate (6–8 criteria/question of yes); weak (1–5 criteria/question of yes).</p></fn></table-wrap-foot></table-wrap><p>The research was heterogeneous; therefore, overall synthesis using meta-analysis was inappropriate (<xref rid="CIT0057" ref-type="bibr">57</xref>). We, therefore, utilised a thematic analysis as a framework for analysis. Thematic analysis involves ‘discovering, interpreting and reporting patterns and clusters of meaning within the data’ (<xref rid="CIT0058" ref-type="bibr">58</xref>, p. 27). As Joff (<xref rid="CIT0059" ref-type="bibr">59</xref>) described, following reading and re-reading of the included articles, we identified themes, and these themes were further examined for their similarities, differences and contradictions. From the review, six major themes emerged: 1) knowledge and awareness about malaria, 2) socio-economic and cultural factors, 3) malaria prevention practice, 4) local concepts and perceptions regarding malaria and 5) health-seeking behaviour factors.</p><sec id="S0003-S20001"><title>Knowledge and awareness about malaria</title><p>Nineteen studies reported that knowledge and awareness are major risk factors in malaria control and prevention in SA, mainly in some parts of India, Bangladesh and Sri Lanka (<xref rid="CIT0025" ref-type="bibr">25</xref>–<xref rid="CIT0028" ref-type="bibr">28</xref>, <xref rid="CIT0030" ref-type="bibr">30</xref>–<xref rid="CIT0033" ref-type="bibr">33</xref>, <xref rid="CIT0035" ref-type="bibr">35</xref>, <xref rid="CIT0036" ref-type="bibr">36</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0039" ref-type="bibr">39</xref>, <xref rid="CIT0045" ref-type="bibr">45</xref>, <xref rid="CIT0047" ref-type="bibr">47</xref>, <xref rid="CIT0048" ref-type="bibr">48</xref>, <xref rid="CIT0051" ref-type="bibr">51</xref>, <xref rid="CIT0052" ref-type="bibr">52</xref>, <xref rid="CIT0055" ref-type="bibr">55</xref>, <xref rid="CIT0056" ref-type="bibr">56</xref>). However, very few studies correctly reported the malaria parasite as a causative agent for malaria disease (<xref rid="CIT0028" ref-type="bibr">28</xref>, <xref rid="CIT0033" ref-type="bibr">33</xref>, <xref rid="CIT0036" ref-type="bibr">36</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>), as well as the modes of transmission (<xref rid="CIT0030" ref-type="bibr">30</xref>, <xref rid="CIT0031" ref-type="bibr">31</xref>, <xref rid="CIT0044" ref-type="bibr">44</xref>, <xref rid="CIT0055" ref-type="bibr">55</xref>). One study conducted in 2010 among
school adolescents reported that only 8.6% (of 1,096 samples) students were aware of the causative agent. There were still some misconceptions about the mode of malaria transmission. The same study reported that over 33% of the students responded that houseflies were implicated in malaria (<xref rid="CIT0031" ref-type="bibr">31</xref>). Another study reported that dirty water and food, person-to-person transfer and rain were considered as modes of malaria transmission, while only 24% of people correctly reported that mosquitoes transmit malaria (<xref rid="CIT0030" ref-type="bibr">30</xref>). Similarly, a qualitative study conducted among pregnant women in India reported the mode of transmission:<disp-quote><p>If anyone eats leftover food, they will get a fever and maybe malaria …. Mosquitoes that had made contact with potentially unclean items such as drains, dirty water, bushes, or food, and mosquitoes born ‘due to dirtiness’ or ‘in garbage’ were listed as causes of malaria … If a mosquito defecates in water that is stored for household drinking then this can also cause malaria. (<xref rid="CIT0030" ref-type="bibr">30</xref>, p. 1012)</p></disp-quote></p><p>Ten studies (<xref rid="CIT0029" ref-type="bibr">29</xref>, <xref rid="CIT0030" ref-type="bibr">30</xref>, <xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0033" ref-type="bibr">33</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0042" ref-type="bibr">42</xref>, <xref rid="CIT0048" ref-type="bibr">48</xref>, <xref rid="CIT0049" ref-type="bibr">49</xref>, <xref rid="CIT0052" ref-type="bibr">52</xref>, <xref rid="CIT0053" ref-type="bibr">53</xref>) highlighted that some participants could not even figure out the symptoms of malaria and its treatment. Likewise, one study carried out in India (Orissa) (<xref rid="CIT0033" ref-type="bibr">33</xref>) reported that only about 86% of the participants (male 92.8%; female 78.3%) had ever heard of the term ‘malaria’, and another study conducted in Pakistan (Jalozai) reported over 42% of the participants were not aware of malaria (<xref rid="CIT0044" ref-type="bibr">44</xref>). The study further noted that participants knew or heard about malaria from multiple sources, that is, from health workers (doctors), neighbours, family members or community leaders. In five studies, it was reported that the media – television, radio, newspaper, internet and posters – were the main source of awareness and knowledge among the participants (<xref rid="CIT0028" ref-type="bibr">28</xref>, <xref rid="CIT0031" ref-type="bibr">31</xref>, <xref rid="CIT0034" ref-type="bibr">34</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0043" ref-type="bibr">43</xref>). The findings of this review noted that generally the level of knowledge and awareness about malaria was not only limited among the general public, but also limited among private healthcare professionals (<xref rid="CIT0047" ref-type="bibr">47</xref>). A survey among Indian private practitioners carried out in 2006 reported that the knowledge of malaria treatment and danger signs was very low among private practitioners; therefore, there were some concerns of malaria deaths of those receiving private healthcare treatment (<xref rid="CIT0060" ref-type="bibr">60</xref>, <xref rid="CIT0061" ref-type="bibr">61</xref>).</p><p>Various symptoms and complications regarding malaria, such as jaundice, acute kidney injury, generalised tonic–clonic convulsions, severe anaemia, shock, metabolic acidosis, hypoglycaemia and hyperpyrexia were found among the patients with <italic>P. vivax</italic> in a study carried out by Nandwani et al. (<xref rid="CIT0042" ref-type="bibr">42</xref>), for which the symptoms are known to have been related with <italic>P. falciparum</italic> malaria in recent times. Despite the level of knowledge and awareness in diagnosing and treating malaria by auxiliary nurse midwives (ANMs) and accredited social health activists (ASHAs) with the use of RDT and ACT, malaria was still not treated on time due to unavailability of drugs (<xref rid="CIT0026" ref-type="bibr">26</xref>, <xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0046" ref-type="bibr">46</xref>).</p></sec><sec id="S0003-S20002"><title>Socio-economic and cultural factors</title><p>Eight studies have reported the gap between the gender (male and female) and health-seeking behaviours in SA, where patriarchal norms, beliefs and perceptions still exist (<xref rid="CIT0026" ref-type="bibr">26</xref>, <xref rid="CIT0029" ref-type="bibr">29</xref>, <xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0040" ref-type="bibr">40</xref>, <xref rid="CIT0044" ref-type="bibr">44</xref>, <xref rid="CIT0046" ref-type="bibr">46</xref>, <xref rid="CIT0050" ref-type="bibr">50</xref>, <xref rid="CIT0051" ref-type="bibr">51</xref>). It was reported that female participants were generally less knowledgeable as compared to male participants about the cause and transmission of malaria (<xref rid="CIT0033" ref-type="bibr">33</xref>, <xref rid="CIT0045" ref-type="bibr">45</xref>). However, a study conducted in Afghanistan reported that Afghan women were surprisingly knowledgeable (over 75%) about cause and prevention of malaria (<xref rid="CIT0036" ref-type="bibr">36</xref>).</p><p>Eight studies highlighted socio-economic factors as barriers to malaria control and prevention in SA (<xref rid="CIT0025" ref-type="bibr">25</xref>, <xref rid="CIT0029" ref-type="bibr">29</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0040" ref-type="bibr">40</xref>, <xref rid="CIT0047" ref-type="bibr">47</xref>, <xref rid="CIT0048" ref-type="bibr">48</xref>, <xref rid="CIT0054" ref-type="bibr">54</xref>, <xref rid="CIT0055" ref-type="bibr">55</xref>). Yadav et al. (<xref rid="CIT0054" ref-type="bibr">54</xref>) reported that the majority of people visited government healthcare facilities for blood examination, diagnosis and treatment, as compared to private healthcare facilities. One study, conducted in India, reported that about 51.7% of the participants were aware that governments were taking some initiatives for the prevention and control of malaria (<xref rid="CIT0031" ref-type="bibr">31</xref>). Yet not every participant could take advantage of the facilities like follow-up, blood examination and medicines for the disease; this is mainly due to the affordability of travelling long distances and insufficient availability of public transport. In addition, four studies reported that the efforts of government health authorities against malaria are generally poor or inadequate mainly due to poor infrastructure, less qualified healthcare practitioners, lack of faith in government medicines, expensive and poor quality treatment, non-compliant or incomplete treatment (irrational and inappropriate treatment, lack of efficacy of drugs, inadequate surveillance and resource-poor health systems) (<xref rid="CIT0028" ref-type="bibr">28</xref>, <xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0050" ref-type="bibr">50</xref>).</p><p>Seven studies reported that socio-economic factors led to an increase in malaria cases in several parts of SA (<xref rid="CIT0026" ref-type="bibr">26</xref>, <xref rid="CIT0027" ref-type="bibr">27</xref>, <xref rid="CIT0029" ref-type="bibr">29</xref>, <xref rid="CIT0040" ref-type="bibr">40</xref>, <xref rid="CIT0048" ref-type="bibr">48</xref>, <xref rid="CIT0050" ref-type="bibr">50</xref>, <xref rid="CIT0054" ref-type="bibr">54</xref>). Therefore, there has been a clear emphasis that the government should focus on socio-economic factors in order to decrease the adverse effects of socio-economic factor attributes, including climate change, in vulnerability to malaria in this region. It was interesting to highlight that in most of the studies, it was reported that the majority of people knew about the use and importance of bed nets, which are considered as one of the potential protective interventions against malaria, but there was no relationship with their use due to affordability of bed nets within poor SA communities (<xref rid="CIT0025" ref-type="bibr">25</xref>, <xref rid="CIT0036" ref-type="bibr">36</xref>, <xref rid="CIT0039" ref-type="bibr">39</xref>, <xref rid="CIT0049" ref-type="bibr">49</xref>, <xref rid="CIT0055" ref-type="bibr">55</xref>).</p></sec><sec id="S0003-S20003"><title>Malaria prevention practice</title><p>Six studies reported various measures to prevent malaria which exist in different parts of SA and that the success of these measures depends on the knowledge of, access to and utilisation of services, as well as a combination of users’ behaviours and healthcare access and quality issues (<xref rid="CIT0028" ref-type="bibr">28</xref>, <xref rid="CIT0035" ref-type="bibr">35</xref>, <xref rid="CIT0036" ref-type="bibr">36</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0047" ref-type="bibr">47</xref>, <xref rid="CIT0051" ref-type="bibr">51</xref>). These studies also highlighted that, despite people's knowledge and awareness about the use of bed nets and their effectiveness, not everyone used them because of the costs, concerns about safety (for pregnant women) and lack of availability (ITN), as well as promotion and pricing, including preferential treatment, as there were some strong perceptions that clinics and salesman prefer to sell these ITNs to their relatives or for profit (<xref rid="CIT0036" ref-type="bibr">36</xref>). Though bed nets in general, and insecticide-treated nets in particular, generally reduce the burdens of malaria, the role of the protective effects of bed nets was not clear when comparing malaria deaths with malaria survivors (<xref rid="CIT0047" ref-type="bibr">47</xref>). The same study explored two possibilities for protective effects: ‘one possibility could be that bed nets reduced the intensity of infection. The other possibility could be that ownership of bed net was a surrogate marker of socio-economic status, through residual confounding’ (p. 5).</p><p>Some studies reported that people used repellent coils, proper clothing that covers the whole body, spray and removal of stagnant water from the environment as preventive practices (<xref rid="CIT0028" ref-type="bibr">28</xref>, <xref rid="CIT0039" ref-type="bibr">39</xref>, <xref rid="CIT0046" ref-type="bibr">46</xref>, <xref rid="CIT0056" ref-type="bibr">56</xref>). However, some ethnic groups in some parts of SA equally preferred traditional methods, like making bonfires, burning grass, rubbing lamp or motor oil on the skin, and sleeping wrapped in wet chadors and applying herbal oil to avoid mosquito bites, practices which were quite prevalent (<xref rid="CIT0030" ref-type="bibr">30</xref>, <xref rid="CIT0036" ref-type="bibr">36</xref>, <xref rid="CIT0045" ref-type="bibr">45</xref>, <xref rid="CIT0053" ref-type="bibr">53</xref>). One study conducted in Afghanistan reported that people often use cooling drinks, such as dough or lassie (from yoghurt), or various plants, the most common of which was a tea from shamaki roots. Shamaki is a Pashtu term for a plant used locally in traditional medicine, and such traditional medicine is usually chosen due to cost (<xref rid="CIT0036" ref-type="bibr">36</xref>). One respondent said:<disp-quote><p>We usually resort to traditional treatment rather than clinical treatment unless the traditional treatment doesn't work. It is due to poverty and people can't afford to cover doctor's and transportation costs. (<xref rid="CIT0036" ref-type="bibr">36</xref>)
</p></disp-quote></p><p>Similarly, another study conducted in Nepal reported that 16.3% (of 1,130) respondents did not consult anywhere and 16.1% consulted with traditional healers, with the reasons provided being lack of time to go to the health services, absence of health professionals in the health services and lack of knowledge of where to go when getting a fever with chills (<xref rid="CIT0038" ref-type="bibr">38</xref>).</p></sec><sec id="S0003-S20004"><title>Concepts and perceptions</title><p>Several studies reported that local people perceived and defined malaria differently, and the perceived symptoms presented by the participants in the study were common cold, typhoid, tuberculosis, skin disease and diarrhoea (<xref rid="CIT0053" ref-type="bibr">53</xref>, <xref rid="CIT0054" ref-type="bibr">54</xref>). Studies carried out by Das and Ravindran (<xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0033" ref-type="bibr">33</xref>) stated that people defined malaria using the term ‘meleria’ and that was equated with the meaning of ‘common disease’ in the community. Likewise, in a study carried out in India, it was found the community called malaria <italic>kakar jwar</italic> or <italic>Pali jwar</italic>, which was the concept often used to describe the symptoms of malaria among the tribes (<xref rid="CIT0054" ref-type="bibr">54</xref>). However, despite the fact that the community gave their own name to the malarial symptoms, the participants clearly understood the term ‘malaria’, and most of the participants were aware that malaria is a serious public health issue (<xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0045" ref-type="bibr">45</xref>, <xref rid="CIT0054" ref-type="bibr">54</xref>). This concept was no different between the LLIN users and non-users. However, people often reported that the degree of the seriousness of the disease was determined by the amount of physical suffering, the degree of daily activities being hindered and having to spend more money on treatment (<xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0036" ref-type="bibr">36</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0051" ref-type="bibr">51</xref>, <xref rid="CIT0055" ref-type="bibr">55</xref>).</p></sec><sec id="S0003-S20005"><title>Health-seeking behaviour</title><p>Seven studies reported that delays in the diagnosis and treatment of malaria, even for a few days, would lead to a fatal outcome (<xref rid="CIT0025" ref-type="bibr">25</xref>, <xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0034" ref-type="bibr">34</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0047" ref-type="bibr">47</xref>, <xref rid="CIT0053" ref-type="bibr">53</xref>, <xref rid="CIT0054" ref-type="bibr">54</xref>). It has been discussed that the community people who suffered from malaria would rather wait for a few more days and help themselves with home remedies. When the disease did not seem to get better, then the adults within the community would seek help from traditional healers (<xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0045" ref-type="bibr">45</xref>, <xref rid="CIT0051" ref-type="bibr">51</xref>). Four studies reported that the delayed treatment and delays in health-seeking practices were mainly due to the long walking distances to access the health facilities, long waiting time, unfriendly health workers, lack of money, loss of faith in the medical profession, lack of people to accompany patients to health services – primarily with small children of those parents who might be busy farming – compounded by difficult terrain, especially during monsoon (<xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0039" ref-type="bibr">39</xref>, <xref rid="CIT0050" ref-type="bibr">50</xref>, <xref rid="CIT0051" ref-type="bibr">51</xref>). Sometimes, it was simply due to some misconceptions; for example, one study conducted in Bhutan reported that still ‘people believe that malaria is caused by bad air, by staying in rain and long hours in sun, by local spirits, and taking fruits with sour taste’ (<xref rid="CIT0051" ref-type="bibr">51</xref>, p. 276; <xref rid="CIT0052" ref-type="bibr">52</xref>, p. 2).</p><p>The responses in the study by Ahmed et al. (<xref rid="CIT0025" ref-type="bibr">25</xref>) showed that the participants wished to go for allopathic treatment rather than seeking modern medicines. This led to delays in seeking healthcare, even when fever was noticed. Similarly, another study reported that people often seek treatment from traditional healers, and this was mainly due to the fact that the community lacks public transport, leading to the need to walk long distances in order to obtain essential healthcare at primary healthcare facilities (<xref rid="CIT0053" ref-type="bibr">53</xref>).</p></sec></sec><sec id="S0004"><title>Discussion and conclusion</title><p>This review examined the knowledge, attitudes and beliefs about malaria in SA. Although problems or concerns represented a diverse list of issues as SA is reasonably heterogeneous in terms of multi-cultural setups, variances in socio-cultural, economic, and demographic profiles, and dissimilar environments which are considered as suitable settings for mosquito-breeding (<xref rid="CIT0056" ref-type="bibr">56</xref>), this study has added significantly to the literature on understanding and practices of prevention and control of malaria in this region. As far as the authors are aware, this is perhaps the first of its kind in terms of research to determine the knowledge, attitudes and beliefs about malaria in this region.</p><p>We found that appropriate understanding and awareness of malaria are considered essential components before taking any informed action for the prevention and treatment of malaria (<xref rid="CIT0026" ref-type="bibr">26</xref>). The study also revealed that factors associated with cost (travel, treatment), distance to access/utilise health services, and perceptions of the healthcare expected from health services have been identified as major determinants that influence people's health-seeking behaviours, as has been clearly documented in other studies (<xref rid="CIT0062" ref-type="bibr">62</xref>, <xref rid="CIT0063" ref-type="bibr">63</xref>).</p><p>Similarly, the findings of the study highlighted that though the knowledge of malaria among some participants was found to be generally high, which was similar to the previous studies conducted in Nigeria (<xref rid="CIT0064" ref-type="bibr">64</xref>), Zimbabwe (<xref rid="CIT0065" ref-type="bibr">65</xref>) and Sudan (<xref rid="CIT0066" ref-type="bibr">66</xref>), the barriers seem mostly to be at the implementation step, largely due to socio-economic and cultural factors. This study has also revealed that those people who were most at risk – mainly children and pregnant women – were not given priority when dealing with preventive and treatment measures at both healthcare and household levels. This was consistent with the findings from Ethiopia's studies (<xref rid="CIT0067" ref-type="bibr">67</xref>, <xref rid="CIT0068" ref-type="bibr">68</xref>) as they reported that malaria mostly affected poor and underserved tribal populations, who lived in remote forest areas, as these people are deprived in terms of access to adequate modern treatment facilities.</p><p>In SA, most of the people are poor and marginalised, their level of education is relatively poor and they mostly live in the remote villages, often deprived of modern healthcare facilities. Several studies supported similar findings stating that people – mainly the tribal or indigenous communities – were less able to obtain appropriate and timely treatment, even for minor illness, and as a result, they not only rely upon unproven traditional methods (<xref rid="CIT0030" ref-type="bibr">30</xref>), but are also obliged to seek inappropriate care due to their low level of knowledge and awareness about the symptoms and seriousness of malaria (<xref rid="CIT0032" ref-type="bibr">32</xref>). That may ultimately lead them to delay treatment. A previous study reported that in 2006, four out of six deaths from malaria occurred due to delayed treatment (<xref rid="CIT0069" ref-type="bibr">69</xref>).</p><p>Evidence suggests that to better understand the challenges or barriers to the prevention and control of malaria, it is important to consider people's geographical and socio-cultural contexts (<xref rid="CIT0050" ref-type="bibr">50</xref>). Malaria is very much linked with environmental determinants, including climate, agriculture, irrigation and forests, which significantly contribute to the variations in malaria incidence (<xref rid="CIT0048" ref-type="bibr">48</xref>). It is, therefore, important to develop intersectoral co-operation or collaboration, working modally in terms of developing environmentally sound mosquito control activities with appropriate community participation (<xref rid="CIT0070" ref-type="bibr">70</xref>, <xref rid="CIT0071" ref-type="bibr">71</xref>). Roll Back Malaria (RBM), an initiative launched jointly in Geneva by the United Nations Children's Emergency Fund (UNICEF), the United Nations Development Programme (UNDP), the World Bank and the WHO, is a people-oriented programme that emphasises community participation (<xref rid="CIT0044" ref-type="bibr">44</xref>).</p><p>The findings of this review have clearly identified that even when there were health services available to people, the cost related to cure and prevention treatment for malaria has prevented the poor from seeking healthcare. Besides that, the cost of malaria prevention intervention measures was found to be more costly in rural areas as compared to urban areas (<xref rid="CIT0045" ref-type="bibr">45</xref>). Similarly, this study noted that the use of bed nets was relatively poor and limited among the participants (<xref rid="CIT0032" ref-type="bibr">32</xref>, <xref rid="CIT0036" ref-type="bibr">36</xref>). Bed nets, mainly ITNs, are reasonably cost-effective and are now considered as an integral component of global malaria control initiatives to decrease malaria cases and malarial mortality, if properly used and maintained (<xref rid="CIT0072" ref-type="bibr">72</xref>). A study conducted in Uganda reported that the prevalence of malaria cases is significantly lower in households with ITNs compared to non-users (9% vs. 14%) (<xref rid="CIT0073" ref-type="bibr">73</xref>). It is, therefore, important to distribute insecticidal nets in a more equitable manner (<xref rid="CIT0074" ref-type="bibr">74</xref>–<xref rid="CIT0076" ref-type="bibr">76</xref>), which is also one of the strategies for global malaria control in terms of achieving the malaria-related Millennium Development Goal (MDG) and RBM targets (<xref rid="CIT0077" ref-type="bibr">77</xref>–<xref rid="CIT0079" ref-type="bibr">79</xref>).</p><p>In SA, there is long experience of using vector control for the prevention and control of malaria (<xref rid="CIT0047" ref-type="bibr">47</xref>). Vector control can help in prevention and control by ‘reducing the vector density or abundance, reducing longevity, and preventing human-vector contact’ (<xref rid="CIT0047" ref-type="bibr">47</xref>, p. 1). The World Health Assembly (<xref rid="CIT0048" ref-type="bibr">48</xref>) has called for support in developing countries’ capacities in expanding the use of effective interventions for malaria control. Indoor residual spraying was the main approach for controlling vector in most parts of SA, but its effectiveness was an issue due to insecticide resistance (<xref rid="CIT0046" ref-type="bibr">46</xref>). Rowland et al. (<xref rid="CIT0014" ref-type="bibr">14</xref>) argue that the standard method of malaria control in SA is indoor spraying of houses with residual insecticide, which is becoming prohibitively expensive to implement. Recently, it has been reported that drug-resistant parasites are prevalent in SA, which would threaten the control and elimination of malaria globally (<xref rid="CIT0002" ref-type="bibr">2</xref>, <xref rid="CIT0033" ref-type="bibr">33</xref>, <xref rid="CIT0038" ref-type="bibr">38</xref>, <xref rid="CIT0047" ref-type="bibr">47</xref>).</p><p>This study was not without some limitations, and it was acknowledged that this study should be evaluated to be certain about the reliability and validity of the conclusion. Hence, any limitation encountered in the research literature studied could also affect the validity of the current study. Our study was not externally funded, and therefore, time and resources were severe constraints. Nonetheless, careful consideration was given to selection of the material for the systematic literature review, on the reliability and validity of the methodologies employed.</p><p>Despite these limitations, we believe that this study has been clearly recognised for its ability to identify the socio-cultural gaps in the research, which is often a neglected area in malaria research in general and the SA population in particular. The study emphasises that control and prevention of malaria prevention would be possible when the social and cultural factors need to be addressed, along with the other factors and the challenges. The regional director, WHO South-East Asia, emphasised that ‘successful and sustainable malaria control would need strong political will, participation of communities at risk of malaria, partnerships between the public, private, health and non-health sectors, and strong technical and management capacities for malaria control at all levels of the public health system’ (<xref rid="CIT0061" ref-type="bibr">61</xref>). Strong disease surveillance, including monitoring and evaluation as well as early diagnosis and proper treatment of malaria, is the major approach, not only in reducing morbidity and mortality caused by malaria, but also leading to the pre-elimination phase of malaria (<xref rid="CIT0061" ref-type="bibr">61</xref>). In addition, given the nature of the findings of the study, it is important to focus on the need to develop appropriate strategies to improve individual and community practices for the prevention and control of malaria through engaging social scientists in terms of conducting formative research as a basis for behaviour-change communications in various socio-cultural settings, as well as addressing other determinants to improve access to malaria interventions. Therefore, there is a need to invest more in social science research to support policy and practices to accelerate progress towards malaria elimination.</p><p>This study concludes that there is a need for changes in people's beliefs, attitudes and behaviours towards using long-lasting insecticide nets and indoor spraying with residual insecticides, as well as seeking early, effective diagnosis, treatment, vector control and personal protection. Adherence to treatment is equally important in bringing lasting change in people's health and livelihoods, which would ultimately accelerate to eliminating malaria. All of this requires training and education, public–private partnerships, and community awareness from SA (<xref rid="CIT0002" ref-type="bibr">2</xref>, <xref rid="CIT0080" ref-type="bibr">80</xref>, <xref rid="CIT0081" ref-type="bibr">81</xref>).</p></sec></body><back><ack><title>Acknowledgements</title><p>The present article is based on the research undertaken for a public health project at the University of Bedfordshire, UK.</p></ack><sec id="S0005"><title>Authors’ contributions</title><p>AK and KR conceived and designed the study with advice from LO; KR, AK and LO reviewed, analysed and interpreted the data and contributed to drafting and finalising the manuscript.</p></sec><sec id="S0006"><title>Conflicts of interests and funding</title><p>The authors have not received any funding or benefits from industry or elsewhere to conduct this study.</p></sec><sec id="S0007"><title>Disclaimer</title><p>The findings and conclusions in this article are by the authors and views expressed in this publication do not necessarily represent the decisions, policy or views of their institutions.</p></sec><ref-list><title>References</title><ref id="CIT0001"><label>1</label><element-citation publication-type="book"><collab>World Health Organization</collab><article-title>Factsheet: vector borne disease</article-title><year>2014</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name><comment>Factsheet #387</comment></element-citation></ref><ref id="CIT0002"><label>2</label><element-citation publication-type="book"><collab>World Health Organization</collab><source>World malaria report</source><year>2015</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="CIT0003"><label>3</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Heymann</surname><given-names>D</given-names></name></person-group><article-title>Control of communicable diseases manual</article-title><year>2015</year><publisher-loc>Washington, DC</publisher-loc><publisher-name>American Public Health Association</publisher-name></element-citation></ref><ref id="CIT0004"><label>4</label><element-citation publication-type="book"><collab>World Health Organization</collab><article-title>South Asian Association for Regional Cooperation: partnership, interagency coordination and resource mobilization</article-title><year>2015</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="CIT0005"><label>5</label><element-citation publication-type="book"><collab>Asian Development Bank</collab><article-title>Malaria data in Asia and the pacific: by the numbers</article-title><year>2013</year><publisher-loc>Metro Manila</publisher-loc><publisher-name>ADB</publisher-name></element-citation></ref><ref id="CIT0006"><label>6</label><element-citation publication-type="book"><collab>World Health Organization</collab><source>World malaria report</source><year>2013</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="CIT0007"><label>7</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rijken</surname><given-names>MJ</given-names></name><name><surname>McGready</surname><given-names>R</given-names></name><name><surname>Boel</surname><given-names>ME</given-names></name><name><surname>Poespoprodjo</surname><given-names>R</given-names></name><name><surname>Singh</surname><given-names>N</given-names></name><name><surname>Syafruddin</surname><given-names>D</given-names></name><etal></etal></person-group><article-title>Malaria in pregnancy in the Asia-Pacific region</article-title><source>Lancet Infect Dis</source><year>2012</year><volume>12</volume><fpage>75</fpage><lpage>88</lpage><pub-id pub-id-type="pmid">22192132</pub-id></element-citation></ref><ref id="CIT0008"><label>8</label><element-citation publication-type="book"><collab>World Health Organization</collab><article-title>WHO calls for greater investment to eliminate malaria</article-title><year>2013</year><publisher-loc>India</publisher-loc><publisher-name>WHO-South East Asia Region</publisher-name></element-citation></ref><ref id="CIT0009"><label>9</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Grietens</surname><given-names>KP</given-names></name><name><surname>Xuan</surname><given-names>XN</given-names></name><name><surname>Ribera</surname><given-names>JM</given-names></name><name><surname>Duc</surname><given-names>TN</given-names></name><name><surname>Bortel</surname><given-names>WV</given-names></name><name><surname>Ba</surname><given-names>NT</given-names></name></person-group><article-title>Low perception of malaria risk among the Ra-glai ethnic minority in south-central Vietnam: implications for forest malaria control</article-title><source>Malar J</source><year>2010</year><volume>9</volume><fpage>23</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-9-23">http://dx.doi.org/10.1186/1475-2875-9-23</ext-link></comment><pub-id pub-id-type="pmid">20089152</pub-id></element-citation></ref><ref id="CIT0010"><label>10</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kumar</surname><given-names>D</given-names></name><name><surname>Kumar</surname><given-names>M</given-names></name><name><surname>Kumar</surname><given-names>A</given-names></name><name><surname>Singh</surname><given-names>SK</given-names></name></person-group><article-title>Chalcone and curcumin derivatives: a way ahead for malarial treatment</article-title><source>Mini Rev Med Chem</source><year>2013</year><volume>13</volume><fpage>2116</fpage><lpage>33</lpage><pub-id pub-id-type="pmid">24160709</pub-id></element-citation></ref><ref id="CIT0011"><label>11</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kumar</surname><given-names>A</given-names></name><name><surname>Chery</surname><given-names>L</given-names></name><name><surname>Biswas</surname><given-names>C</given-names></name><name><surname>Dubhashi</surname><given-names>N</given-names></name><name><surname>Dutta</surname><given-names>P</given-names></name><name><surname>Kumar</surname><given-names>V</given-names></name><etal></etal></person-group><article-title>Malaria in South Asia: prevalence and control</article-title><source>Acta Trop</source><year>2012</year><volume>121</volume><fpage>246</fpage><lpage>55</lpage><pub-id pub-id-type="pmid">22248528</pub-id></element-citation></ref><ref id="CIT0012"><label>12</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Leslie</surname><given-names>T</given-names></name><name><surname>Mayan</surname><given-names>MI</given-names></name><name><surname>Hasan</surname><given-names>MA</given-names></name><name><surname>Safi</surname><given-names>MH</given-names></name><name><surname>Klinkenberg</surname><given-names>E</given-names></name><name><surname>Whitty</surname><given-names>CJM</given-names></name><etal></etal></person-group><article-title>Sulfadoxine-pyrimethamine, chlorproguanil-dapsone, or chloroquine for the treatment of plasmodium vivax malaria in Afghanistan and Pakistan: a randomized controlled trial</article-title><source>JAMA</source><year>2007</year><volume>297</volume><fpage>2201</fpage><lpage>9</lpage><pub-id pub-id-type="pmid">17519409</pub-id></element-citation></ref><ref id="CIT0013"><label>13</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Khatoon</surname><given-names>L</given-names></name><name><surname>Khan</surname><given-names>IU</given-names></name><name><surname>Shah</surname><given-names>SA</given-names></name><name><surname>Jan</surname><given-names>MI</given-names></name><name><surname>Ullah</surname><given-names>F</given-names></name><name><surname>Malik</surname><given-names>SA</given-names></name></person-group><article-title>Genetic diversity of <italic>Plasmodium vivax</italic> and <italic>Plasmodium falciparum</italic> in Kohat district, Pakistan</article-title><source>Braz J Infect Dis</source><year>2012</year><volume>16</volume><fpage>184</fpage><lpage>7</lpage><pub-id pub-id-type="pmid">22552463</pub-id></element-citation></ref><ref id="CIT0014"><label>14</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rowland</surname><given-names>M</given-names></name><name><surname>Durrani</surname><given-names>N</given-names></name><name><surname>Kenward</surname><given-names>M</given-names></name><name><surname>Mohammed</surname><given-names>N</given-names></name><name><surname>Urahman</surname><given-names>H</given-names></name><name><surname>Hewitt</surname><given-names>S</given-names></name></person-group><article-title>Control of malaria in Pakistan by applying deltamethrin insecticide to cattle: a community-randomised trial</article-title><source>Lancet</source><year>2001</year><volume>357</volume><fpage>1837</fpage><lpage>41</lpage><pub-id pub-id-type="pmid">11410192</pub-id></element-citation></ref><ref id="CIT0015"><label>15</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sharma</surname><given-names>R</given-names></name><name><surname>Thakor</surname><given-names>H</given-names></name><name><surname>Saha</surname><given-names>K</given-names></name><name><surname>Sonal</surname><given-names>G</given-names></name><name><surname>Dhariwal</surname><given-names>A</given-names></name><name><surname>Singh</surname><given-names>N</given-names></name></person-group><article-title>Malaria situation in India with special reference to tribal areas</article-title><source>Indian J Med Res</source><year>2015</year><volume>141</volume><fpage>537</fpage><lpage>45</lpage><pub-id pub-id-type="pmid">26139770</pub-id></element-citation></ref><ref id="CIT0016"><label>16</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Dhillon</surname><given-names>HS</given-names></name><name><surname>Kar</surname><given-names>SB</given-names></name></person-group><article-title>Investigation of cultural patterns and beliefs among tribal populations in Orissa with regard to malaria eradication activities</article-title><year>1963</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="CIT0017"><label>17</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bates</surname><given-names>I</given-names></name><name><surname>Fenton</surname><given-names>C</given-names></name><name><surname>Gruber</surname><given-names>J</given-names></name><name><surname>Lalloo</surname><given-names>D</given-names></name><name><surname>Lara</surname><given-names>AM</given-names></name><name><surname>Medina</surname><given-names>Lara A</given-names></name><etal></etal></person-group><article-title>Vulnerability to malaria, tuberculosis, and HIV/AIDS infection and disease. Part 1: determinants operating at individual and household level</article-title><source>Lancet Infect Dis</source><year>2004</year><volume>4</volume><fpage>267</fpage><lpage>77</lpage><pub-id pub-id-type="pmid">15120343</pub-id></element-citation></ref><ref id="CIT0018"><label>18</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Dash</surname><given-names>AP</given-names></name><name><surname>Valecha</surname><given-names>N</given-names></name><name><surname>Anvikar</surname><given-names>AR</given-names></name><name><surname>Kumar</surname><given-names>A</given-names></name></person-group><article-title>Malaria in India: challenges and opportunities</article-title><source>J Biosci</source><year>2008</year><volume>33</volume><fpage>583</fpage><lpage>92</lpage><pub-id pub-id-type="pmid">19208983</pub-id></element-citation></ref><ref id="CIT0019"><label>19</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Boland</surname><given-names>A</given-names></name><name><surname>Cherry</surname><given-names>M</given-names></name><name><surname>Dickson</surname><given-names>R</given-names></name></person-group><article-title>Doing a systematic review: a student's guide</article-title><year>2014</year><publisher-loc>London</publisher-loc><publisher-name>Sage</publisher-name></element-citation></ref><ref id="CIT0020"><label>20</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mays</surname><given-names>N</given-names></name><name><surname>Pope</surname><given-names>C</given-names></name><name><surname>Popay</surname><given-names>J</given-names></name></person-group><article-title>Systematically reviewing qualitative and quantitative evidence to inform management and policy-making in the health field</article-title><source>J Health Serv Res Policy</source><year>2005</year><volume>10</volume><fpage>6</fpage><lpage>20</lpage><pub-id pub-id-type="pmid">16053580</pub-id></element-citation></ref><ref id="CIT0021"><label>21</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Guyatt</surname><given-names>G</given-names></name><name><surname>Rennie</surname><given-names>D</given-names></name></person-group><article-title>User's guides to the medical literature: a manual for evidence-based clinical practice</article-title><year>2002</year><publisher-loc>Chicago, IL</publisher-loc><publisher-name>American Medical Association</publisher-name></element-citation></ref><ref id="CIT0022"><label>22</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Garg</surname><given-names>AX</given-names></name><name><surname>Hackam</surname><given-names>D</given-names></name><name><surname>Tonelli</surname><given-names>M</given-names></name></person-group><article-title>Systematic review and meta-analysis: when one study is just not enough</article-title><source>Clin J Am Soc Nephrol</source><year>2008</year><volume>3</volume><fpage>253</fpage><lpage>60</lpage><pub-id pub-id-type="pmid">18178786</pub-id></element-citation></ref><ref id="CIT0023"><label>23</label><element-citation publication-type="book"><collab>Institute of Medicine</collab><article-title>Finding what works in healthcare: standards for systematic review</article-title><year>2011</year><publisher-loc>Washington, DC</publisher-loc><publisher-name>The National Academic Press</publisher-name></element-citation></ref><ref id="CIT0024"><label>24</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Smith</surname><given-names>KE</given-names></name><name><surname>Bambra</surname><given-names>C</given-names></name><name><surname>Joyce</surname><given-names>KE</given-names></name><name><surname>Perkins</surname><given-names>N</given-names></name><name><surname>Hunter</surname><given-names>DJ</given-names></name></person-group><article-title>Partners in health? A systematic review of the impact of organizational partnerships on public health outcomes in England between 1997 and 2008</article-title><source>J Public Health (Oxf)</source><year>2009</year><volume>1</volume><fpage>210</fpage><lpage>21</lpage><pub-id pub-id-type="pmid">19182048</pub-id></element-citation></ref><ref id="CIT0025"><label>25</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ahmed</surname><given-names>SM</given-names></name><name><surname>Haque</surname><given-names>R</given-names></name><name><surname>Haque</surname><given-names>U</given-names></name><name><surname>Hossain</surname><given-names>A</given-names></name></person-group><article-title>Knowledge on the transmission, prevention and treatment of malaria among two endemic populations of Bangladesh and their health-seeking behavior</article-title><source>Malar J</source><year>2009</year><volume>8</volume><fpage>173</fpage><pub-id pub-id-type="pmid">19640282</pub-id></element-citation></ref><ref id="CIT0026"><label>26</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ahmed</surname><given-names>SM</given-names></name><name><surname>Hossain</surname><given-names>SM</given-names></name><name><surname>Kabir</surname><given-names>M</given-names></name></person-group><article-title>Conventional or interpersonal communication: which works best in disseminating malaria information in an endemic rural Bangladeshi community?</article-title><source>PLoS One</source><year>2014</year><volume>9</volume><fpage>e90711</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1371/journal.pone.0090711">http://dx.doi.org/10.1371/journal.pone.0090711</ext-link></comment><pub-id pub-id-type="pmid">24603849</pub-id></element-citation></ref><ref id="CIT0027"><label>27</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ahmed</surname><given-names>SM</given-names></name><name><surname>Hossain</surname><given-names>S</given-names></name><name><surname>Kabir</surname><given-names>MM</given-names></name><name><surname>Roy</surname><given-names>S</given-names></name></person-group><article-title>Free distribution of insecticidal bed nets improves possession and preferential use by households and is equitable: findings from two cross-sectional surveys in thirteen malaria endemic districts of Bangladesh</article-title><source>Malar J</source><year>2011</year><volume>10</volume><fpage>357</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-10-357">http://dx.doi.org/10.1186/1475-2875-10-357</ext-link></comment><pub-id pub-id-type="pmid">22165959</pub-id></element-citation></ref><ref id="CIT0028"><label>28</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Anand</surname><given-names>T</given-names></name><name><surname>Kumar</surname><given-names>R</given-names></name><name><surname>Saini</surname><given-names>V</given-names></name><name><surname>Meena</surname><given-names>G</given-names></name><name><surname>Ingle</surname><given-names>G</given-names></name></person-group><article-title>Knowledge and use of personal protective measures against mosquito borne diseases in a resettlement colony of Delhi</article-title><source>Ann Med Health Sci Res</source><year>2014</year><volume>4</volume><fpage>227</fpage><lpage>32</lpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.4103/2141-9248.129048">http://dx.doi.org/10.4103/2141-9248.129048</ext-link></comment><pub-id pub-id-type="pmid">24761243</pub-id></element-citation></ref><ref id="CIT0029"><label>29</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bashar</surname><given-names>K</given-names></name><name><surname>Al-Amin</surname><given-names>HM</given-names></name><name><surname>Reza</surname><given-names>MS</given-names></name><name><surname>Islam</surname><given-names>M</given-names></name><name><surname>Asaduzzaman</surname></name><name><surname>Ahmed</surname><given-names>TU</given-names></name></person-group><article-title>Socio-demographic factors influencing knowledge, attitude and practice (KAP) regarding malaria in Bangladesh</article-title><source>BMC Public Health</source><year>2012</year><volume>12</volume><fpage>1084</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1471-2458-12-1084">http://dx.doi.org/10.1186/1471-2458-12-1084</ext-link></comment><pub-id pub-id-type="pmid">23253186</pub-id></element-citation></ref><ref id="CIT0030"><label>30</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Chourasia</surname><given-names>MK</given-names></name><name><surname>Abraham</surname><given-names>VJ</given-names></name><name><surname>John</surname><given-names>J</given-names></name></person-group><article-title>Household training vs. mass campaigns: a better method of health communication for preventing malaria</article-title><source>Trop Doct</source><year>2014</year><volume>44</volume><fpage>196</fpage><lpage>200</lpage><pub-id pub-id-type="pmid">25161177</pub-id></element-citation></ref><ref id="CIT0031"><label>31</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Dambhare</surname><given-names>DG</given-names></name><name><surname>Nimgade</surname><given-names>SD</given-names></name><name><surname>Dudhe</surname><given-names>JY</given-names></name></person-group><article-title>Knowledge, attitude and practice of malaria transmission and its prevention among the school going adolescents in Wardha District, Central India</article-title><source>Glob J Health Sci</source><year>2012</year><volume>4</volume><fpage>76</fpage><lpage>82</lpage><pub-id pub-id-type="pmid">22980344</pub-id></element-citation></ref><ref id="CIT0032"><label>32</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Das</surname><given-names>A</given-names></name><name><surname>Ravindran</surname><given-names>TS</given-names></name></person-group><article-title>Factors affecting treatment-seeking for febrile illness in a malaria endemic block in Boudh district, Orissa, India: policy implications for malaria control</article-title><source>Malar J</source><year>2010</year><volume>9</volume><fpage>377</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-9-377">http://dx.doi.org/10.1186/1475-2875-9-377</ext-link></comment><pub-id pub-id-type="pmid">21192825</pub-id></element-citation></ref><ref id="CIT0033"><label>33</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Das</surname><given-names>A</given-names></name><name><surname>Ravindran</surname><given-names>TS</given-names></name></person-group><article-title>Community knowledge on malaria among febrile patients in an endemic district of Orissa, India</article-title><source>J Vector Borne Dis</source><year>2011</year><volume>48</volume><fpage>46</fpage><lpage>51</lpage><pub-id pub-id-type="pmid">21406737</pub-id></element-citation></ref><ref id="CIT0034"><label>34</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Dhawan</surname><given-names>G</given-names></name><name><surname>Joseph</surname><given-names>N</given-names></name><name><surname>Pekow</surname><given-names>PS</given-names></name><name><surname>Rogers</surname><given-names>CA</given-names></name><name><surname>Poudel</surname><given-names>KC</given-names></name><name><surname>Bulzacchelli</surname><given-names>MT</given-names></name></person-group><article-title>Malaria-related knowledge and prevention practices in four neighborhoods in and around Mumbai: a cross sectional study</article-title><source>Malar J</source><year>2014</year><volume>13</volume><fpage>303</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-13-303">http://dx.doi.org/10.1186/1475-2875-13-303</ext-link></comment><pub-id pub-id-type="pmid">25102949</pub-id></element-citation></ref><ref id="CIT0035"><label>35</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fernando</surname><given-names>SD</given-names></name><name><surname>Abeyasinghe</surname><given-names>RR</given-names></name><name><surname>Galappaththy</surname><given-names>GN</given-names></name><name><surname>Gunawardena</surname><given-names>N</given-names></name><name><surname>Rajapakse</surname><given-names>LC</given-names></name></person-group><article-title>Community factors affecting long-lasting impregnated mosquito net use for malaria control in Sri Lanka</article-title><source>Trans R Soc Trop Med Hyg</source><year>2008</year><volume>102</volume><fpage>1081</fpage><lpage>8</lpage><pub-id pub-id-type="pmid">18644611</pub-id></element-citation></ref><ref id="CIT0036"><label>36</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Howard</surname><given-names>N</given-names></name><name><surname>Shafi</surname><given-names>A</given-names></name><name><surname>Jones</surname><given-names>A</given-names></name><name><surname>Rowland</surname><given-names>M</given-names></name></person-group><article-title>Malaria control under the Taliban regime: insecticide-treated net purchasing, coverage, and usage among men and women in eastern Afghanistan</article-title><source>Malar J</source><year>2010</year><volume>9</volume><fpage>7</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-9-7">http://dx.doi.org/10.1186/1475-2875-9-7</ext-link></comment><pub-id pub-id-type="pmid">20053281</pub-id></element-citation></ref><ref id="CIT0037"><label>37</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hussain</surname><given-names>MA</given-names></name><name><surname>Dandona</surname><given-names>L</given-names></name><name><surname>Schellenberg</surname><given-names>D</given-names></name></person-group><article-title>Public health system readiness to treat malaria in Odisha State of India</article-title><source>Malar J</source><year>2013</year><volume>12</volume><fpage>351</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-12-351">http://dx.doi.org/10.1186/1475-2875-12-351</ext-link></comment><pub-id pub-id-type="pmid">24088525</pub-id></element-citation></ref><ref id="CIT0038"><label>38</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Joshi</surname><given-names>A</given-names></name><name><surname>Banjara</surname><given-names>MR</given-names></name></person-group><article-title>Malaria related knowledge, practices and behaviour of people in Nepal</article-title><source>J Vector Borne Dis</source><year>2008</year><volume>45</volume><fpage>44</fpage><lpage>50</lpage><pub-id pub-id-type="pmid">18399316</pub-id></element-citation></ref><ref id="CIT0039"><label>39</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kirkby</surname><given-names>K</given-names></name><name><surname>Galappaththy</surname><given-names>GN</given-names></name><name><surname>Kurinczuk</surname><given-names>JJ</given-names></name><name><surname>Rajapakse</surname><given-names>S</given-names></name><name><surname>Fernando</surname><given-names>SD</given-names></name></person-group><article-title>Knowledge, attitudes and practices relevant to malaria elimination amongst resettled populations in a post-conflict district of northern Sri Lanka</article-title><source>Trans R Soc Trop Med Hyg</source><year>2013</year><volume>107</volume><fpage>110</fpage><lpage>18</lpage><pub-id pub-id-type="pmid">23222949</pub-id></element-citation></ref><ref id="CIT0040"><label>40</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kumar</surname><given-names>DS</given-names></name><name><surname>Andimuthu</surname><given-names>R</given-names></name><name><surname>Rajan</surname><given-names>R</given-names></name><name><surname>Venkatesan</surname><given-names>MS</given-names></name></person-group><article-title>Spatial trend, environmental and socioeconomic factors associated with malaria prevalence in Chennai</article-title><source>Malar J</source><year>2014</year><volume>13</volume><fpage>14</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-13-14">http://dx.doi.org/10.1186/1475-2875-13-14</ext-link></comment><pub-id pub-id-type="pmid">24400592</pub-id></element-citation></ref><ref id="CIT0041"><label>41</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lwin</surname><given-names>MO</given-names></name><name><surname>Vijaykumar</surname><given-names>S</given-names></name><name><surname>Lim</surname><given-names>G</given-names></name><name><surname>Theng</surname><given-names>YL</given-names></name><name><surname>Foo</surname><given-names>S</given-names></name></person-group><article-title>‘It's effective but should I bother?’ A study of personal protection measures against malaria in urban India</article-title><source>Public Health</source><year>2014</year><volume>128</volume><fpage>654</fpage><lpage>64</lpage><pub-id pub-id-type="pmid">25065519</pub-id></element-citation></ref><ref id="CIT0042"><label>42</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Nandwani</surname><given-names>S</given-names></name><name><surname>Pande</surname><given-names>A</given-names></name><name><surname>Saluja</surname><given-names>M</given-names></name></person-group><article-title>Clinical profile of severe malaria: study from a tertiary care center in north India</article-title><source>J Parasit Dis</source><year>2014</year><volume>38</volume><fpage>11</fpage><lpage>15</lpage><pub-id pub-id-type="pmid">24505170</pub-id></element-citation></ref><ref id="CIT0043"><label>43</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Pandit</surname><given-names>N</given-names></name><name><surname>Patel</surname><given-names>Y</given-names></name><name><surname>Bhavsar</surname><given-names>B</given-names></name></person-group><article-title>Awareness and practice about preventive method against mosquito bite in Gujarat</article-title><source>Healthline</source><year>2010</year><volume>1</volume><fpage>16</fpage><lpage>20</lpage></element-citation></ref><ref id="CIT0044"><label>44</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Qayum</surname><given-names>M</given-names></name><name><surname>Zahur</surname><given-names>H</given-names></name><name><surname>Ahmad</surname><given-names>N, IIyas M</given-names></name><name><surname>Khan</surname><given-names>A</given-names></name><name><surname>Khan</surname><given-names>S</given-names></name></person-group><article-title>SPHERE-based assessment of knowledge and preventive measures related to malaria among the displaced population of Jalozai, Pakistan</article-title><source>J Pak Med Assoc</source><year>2012</year><volume>62</volume><fpage>344</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">22755277</pub-id></element-citation></ref><ref id="CIT0045"><label>45</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sabin</surname><given-names>LL</given-names></name><name><surname>Rizal</surname><given-names>A</given-names></name><name><surname>Brooks</surname><given-names>MI</given-names></name><name><surname>Singh</surname><given-names>MP</given-names></name><name><surname>Tuchman</surname><given-names>J</given-names></name><name><surname>Wylie</surname><given-names>BJ</given-names></name><etal></etal></person-group><article-title>Attitudes knowledge, and practices regarding malaria prevention and treatment among pregnant women in Eastern, India</article-title><source>Am J Trop Med Hyg</source><year>2010</year><volume>82</volume><fpage>1010</fpage><lpage>16</lpage><pub-id pub-id-type="pmid">20519593</pub-id></element-citation></ref><ref id="CIT0046"><label>46</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Saha</surname><given-names>KB</given-names></name><name><surname>Sharma</surname><given-names>RK</given-names></name><name><surname>Mishra</surname><given-names>R</given-names></name><name><surname>Verma</surname><given-names>R</given-names></name><name><surname>Tiwart</surname><given-names>BK</given-names></name><name><surname>Singh</surname><given-names>N</given-names></name></person-group><article-title>Establishing communication mechanism for malaria prevention in Baiga tribal villages in Baiga Chak area of Dindori district, Madhya Pradesh</article-title><source>Indian J Med Res</source><year>2015</year><volume>141</volume><fpage>576</fpage><lpage>83</lpage><pub-id pub-id-type="pmid">26139774</pub-id></element-citation></ref><ref id="CIT0047"><label>47</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sarkar</surname><given-names>J</given-names></name><name><surname>Murhekar</surname><given-names>MV</given-names></name><name><surname>Shah</surname><given-names>NK</given-names></name><name><surname>van Hutin</surname><given-names>Y</given-names></name></person-group><article-title>Risk factors for malaria deaths in Jalpaiguri district, West Bengal, India: evidence for further action</article-title><source>Mala J</source><year>2009</year><volume>8</volume><fpage>133</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-8-133">http://dx.doi.org/10.1186/1475-2875-8-133</ext-link></comment></element-citation></ref><ref id="CIT0048"><label>48</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sharma</surname><given-names>RK</given-names></name><name><surname>Singh</surname><given-names>MP</given-names></name><name><surname>Saha</surname><given-names>KB</given-names></name><name><surname>Bharti</surname><given-names>PK</given-names></name><name><surname>Jain</surname><given-names>V</given-names></name><name><surname>Singh</surname><given-names>PP</given-names></name><etal></etal></person-group><article-title>Socio-economic & household risk factors of malaria in tribal areas of Madhya Pradesh, central India</article-title><source>Indian J Med Res</source><year>2015</year><volume>141</volume><fpage>567</fpage><lpage>75</lpage><pub-id pub-id-type="pmid">26139773</pub-id></element-citation></ref><ref id="CIT0049"><label>49</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sood</surname><given-names>RD</given-names></name><name><surname>Mittal</surname><given-names>PK</given-names></name><name><surname>Kapoor</surname><given-names>N</given-names></name><name><surname>Razdan</surname><given-names>RK</given-names></name><name><surname>Dua</surname><given-names>VK</given-names></name><name><surname>Dash</surname><given-names>AP</given-names></name></person-group><article-title>Community awareness, perceptions, acceptability and preferences for using LLIN against malaria in villages of Uttar Pradesh, India</article-title><source>J Vector Borne Dis</source><year>2010</year><volume>47</volume><fpage>243</fpage><lpage>8</lpage><pub-id pub-id-type="pmid">21178218</pub-id></element-citation></ref><ref id="CIT0050"><label>50</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Sundararajan</surname><given-names>R</given-names></name><name><surname>Kalkonde</surname><given-names>Y</given-names></name><name><surname>Gokhale</surname><given-names>C</given-names></name><name><surname>Greenough</surname><given-names>PG</given-names></name><name><surname>Bang</surname><given-names>A</given-names></name></person-group><article-title>Barriers to malaria control among marginalized tribal communities: a qualitative study</article-title><source>PLoS One</source><year>2013</year><volume>8</volume><fpage>e81966</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1371/journal.pone.0081966">http://dx.doi.org/10.1371/journal.pone.0081966</ext-link></comment><pub-id pub-id-type="pmid">24376507</pub-id></element-citation></ref><ref id="CIT0051"><label>51</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tobgay</surname><given-names>T</given-names></name><name><surname>Lhazeen</surname><given-names>K</given-names></name></person-group><article-title>2010 malaria perceptions and practices in Bhutan</article-title><source>Southeast Asian J Trop Med Public Health</source><year>2010</year><volume>41</volume><fpage>274</fpage><lpage>9</lpage><pub-id pub-id-type="pmid">20578508</pub-id></element-citation></ref><ref id="CIT0052"><label>52</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tobgay</surname><given-names>T</given-names></name><name><surname>Pem</surname><given-names>D</given-names></name><name><surname>Dophu</surname><given-names>U</given-names></name><name><surname>Dumre</surname><given-names>SP</given-names></name><name><surname>Na-Bangchang</surname><given-names>K</given-names></name><name><surname>Torres</surname><given-names>CE</given-names></name></person-group><article-title>Community-directed educational intervention for malaria elimination in Bhutan: quasi-experimental study in malaria endemic areas of Sarpang district</article-title><source>Malar J</source><year>2013</year><volume>12</volume><fpage>132</fpage><comment>doi: <ext-link ext-link-type="uri" xlink:href="http://dx.doi.org/10.1186/1475-2875-12-132">http://dx.doi.org/10.1186/1475-2875-12-132</ext-link></comment><pub-id pub-id-type="pmid">23590625</pub-id></element-citation></ref><ref id="CIT0053"><label>53</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Vijayakumar</surname><given-names>KN</given-names></name><name><surname>Gunasekaran</surname><given-names>K</given-names></name><name><surname>Sahu</surname><given-names>SS</given-names></name><name><surname>Jambulingam</surname><given-names>P</given-names></name></person-group><article-title>Knowledge, attitude and practice on malaria: a study in a tribal belt of Orissa State, India with reference to use of long lasting treated mosquito nets</article-title><source>Acta Trop</source><year>2009</year><volume>112</volume><fpage>137</fpage><lpage>42</lpage><pub-id pub-id-type="pmid">19631184</pub-id></element-citation></ref><ref id="CIT0054"><label>54</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yadav</surname><given-names>SP</given-names></name><name><surname>Yadav</surname><given-names>S</given-names></name><name><surname>Kuma</surname><given-names>P</given-names></name><name><surname>Yadav</surname><given-names>S</given-names></name></person-group><article-title>Knowledge, treatment-seeking behaviour and socio-economic impact of malaria in the desert of Rajasthan, India</article-title><source>South Afr J Epidemiol Infect</source><year>2013</year><volume>28</volume><fpage>41</fpage><lpage>7</lpage></element-citation></ref><ref id="CIT0055"><label>55</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yasuoka</surname><given-names>J</given-names></name><name><surname>Mangione</surname><given-names>TW</given-names></name><name><surname>Spielman</surname><given-names>A</given-names></name><name><surname>Levins</surname><given-names>R</given-names></name></person-group><article-title>Impact of education on knowledge, agricultural practices, and community actions for mosquito control and mosquito-borne disease prevention in rice ecosystems in Sri Lanka</article-title><source>Am J Trop Med Hyg</source><year>2006</year><volume>74</volume><fpage>1034</fpage><lpage>42</lpage><pub-id pub-id-type="pmid">16760516</pub-id></element-citation></ref><ref id="CIT0056"><label>56</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Zaidi</surname><given-names>SA</given-names></name><name><surname>Kokab</surname><given-names>F</given-names></name><name><surname>Bukhari</surname><given-names>IA</given-names></name><name><surname>Nasir</surname><given-names>JA</given-names></name></person-group><article-title>The quantitative evidence of malarial transmission and its associates in Bahawalpur, Pakistan</article-title><source>J Ayub Med Coll Abbottabad</source><year>2015</year><volume>27</volume><fpage>164</fpage><lpage>7</lpage><pub-id pub-id-type="pmid">26182766</pub-id></element-citation></ref><ref id="CIT0057"><label>57</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Thomas</surname><given-names>J</given-names></name><name><surname>Harden</surname><given-names>A</given-names></name></person-group><article-title>Methods for the thematic analysis of qualitative research in systematic reviews</article-title><source>BMC Med Res Methodol</source><year>2008</year><volume>8</volume><fpage>45</fpage><pub-id pub-id-type="pmid">18616818</pub-id></element-citation></ref><ref id="CIT0058"><label>58</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Ritchie</surname><given-names>J</given-names></name><name><surname>Lewis</surname><given-names>J</given-names></name><name><surname>Nicholas</surname><given-names>CM</given-names></name><name><surname>Ormston</surname><given-names>R</given-names></name></person-group><article-title>Qualitative research practice: a guide for social science student and researchers</article-title><year>2014</year><publisher-loc>London</publisher-loc><publisher-name>Sage</publisher-name></element-citation></ref><ref id="CIT0059"><label>59</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Joff</surname><given-names>H</given-names></name></person-group><person-group person-group-type="editor"><name><surname>Harper</surname><given-names>D</given-names></name><name><surname>Thompson</surname><given-names>A</given-names></name></person-group><article-title>Thematic analysis</article-title><source><italic>Qualitative research methods in mental health and psychotherapy: an introduction for students and practitioners</italic></source><year>2012</year><publisher-loc>Chichester</publisher-loc><publisher-name>Wiley-Blackwell</publisher-name><fpage>209</fpage><lpage>24</lpage></element-citation></ref><ref id="CIT0060"><label>60</label><element-citation publication-type="confproc"><person-group person-group-type="author"><name><surname>Sharma</surname><given-names>PK</given-names></name><name><surname>Sen</surname><given-names>TK</given-names></name><name><surname>Ramakrishnan</surname><given-names>R</given-names></name><name><surname>Hutin</surname><given-names>Y</given-names></name><name><surname>Gupte</surname><given-names>MD</given-names></name></person-group><article-title>Lack of access to public health care, shift towards unqualified private providers and malaria deaths in Jalpaiguri district, West Bengal, India, 2006</article-title><source>Poster presented at the Bi-regional Tephinet conference in Taiwan</source><year>2007</year><month>11</month></element-citation></ref><ref id="CIT0061"><label>61</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mishra</surname><given-names>SK</given-names></name><name><surname>Mohanty</surname><given-names>S</given-names></name><name><surname>Das</surname><given-names>BS</given-names></name></person-group><article-title>The influence of healthcare facilities on malarial mortality in and around Rourkela, India</article-title><source>Ann Trop Med Parasitol</source><year>2002</year><volume>96</volume><fpage>835</fpage><lpage>37</lpage><pub-id pub-id-type="pmid">12625939</pub-id></element-citation></ref><ref id="CIT0062"><label>62</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Konradsen</surname><given-names>F</given-names></name><name><surname>van der Hoek</surname><given-names>W</given-names></name><name><surname>Amerasinghe</surname><given-names>PH</given-names></name><name><surname>Amerasinghe</surname><given-names>FP</given-names></name><name><surname>Fonseka</surname><given-names>KT</given-names></name></person-group><article-title>Household responses to malaria and their costs: a study from rural Sri Lanka</article-title><source>Trans R Soc Trop Med Hyg</source><year>1997</year><volume>91</volume><fpage>127</fpage><lpage>30</lpage><pub-id pub-id-type="pmid">9196747</pub-id></element-citation></ref><ref id="CIT0063"><label>63</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Williams</surname><given-names>HA</given-names></name><name><surname>Jones</surname><given-names>CO</given-names></name></person-group><article-title>A critical review of behavioral issues related to malaria control in sub-Saharan Africa: what contributions have social scientists made?</article-title><source>Soc Sci Med</source><year>2004</year><volume>59</volume><fpage>501</fpage><lpage>23</lpage><pub-id pub-id-type="pmid">15144761</pub-id></element-citation></ref><ref id="CIT0064"><label>64</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Udonwa</surname><given-names>NE</given-names></name><name><surname>Gyuse</surname><given-names>AN</given-names></name><name><surname>Etokidem</surname><given-names>AJ</given-names></name></person-group><article-title>Malaria: knowledge and prevention practices among school adolescents in a coastal community in Calabar, Nigeria</article-title><source>Afr J Prm Health Care Fam Med</source><year>2010</year><volume>2</volume><fpage>103</fpage></element-citation></ref><ref id="CIT0065"><label>65</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Midzi</surname><given-names>N</given-names></name><name><surname>Mtapuri-Zinyowera</surname><given-names>S</given-names></name><name><surname>Mapingure</surname><given-names>MP</given-names></name><name><surname>Paul</surname><given-names>NH</given-names></name><name><surname>Sangweme</surname><given-names>D</given-names></name><name><surname>Hlerema</surname><given-names>G</given-names></name><etal></etal></person-group><article-title>Knowledge attitudes and practices of grade three primary schoolchildren in relation to schistosomiasis, soil transmitted helminthiasis and malaria in Zimbabwe</article-title><source>BMC Infect Dis</source><year>2011</year><volume>11</volume><fpage>169</fpage><pub-id pub-id-type="pmid">21668948</pub-id></element-citation></ref><ref id="CIT0066"><label>66</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Erhun</surname><given-names>WO</given-names></name><name><surname>Agbani</surname><given-names>EO</given-names></name><name><surname>Adesanya</surname><given-names>SO</given-names></name></person-group><article-title>Malaria prevention: knowledge, attitude and practice in a Southwestern Nigerian community</article-title><source>Afr J Biomed Res</source><year>2005</year><volume>8</volume><fpage>25</fpage><lpage>9</lpage></element-citation></ref><ref id="CIT0067"><label>67</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Loha</surname><given-names>E</given-names></name><name><surname>Tefera</surname><given-names>K</given-names></name><name><surname>Lindtjørn</surname><given-names>B</given-names></name></person-group><article-title>Freely distributed bed-net use among Chano Mille residents, south Ethiopia: a longitudinal study</article-title><source>Malar J</source><year>2013</year><volume>12</volume><fpage>23</fpage><pub-id pub-id-type="pmid">23331899</pub-id></element-citation></ref><ref id="CIT0068"><label>68</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Deribew</surname><given-names>A</given-names></name><name><surname>Birhanu</surname><given-names>Z</given-names></name><name><surname>Sena</surname><given-names>L</given-names></name><name><surname>Dejene</surname><given-names>T</given-names></name><name><surname>Reda</surname><given-names>AA</given-names></name><name><surname>Sudhakar</surname><given-names>M</given-names></name><etal></etal></person-group><article-title>The effect of household heads training on long-lasting insecticide-treated bed nets utilization: a cluster randomized controlled trial in Ethiopia</article-title><source>Malar J</source><year>2012</year><volume>11</volume><fpage>99</fpage><pub-id pub-id-type="pmid">22463488</pub-id></element-citation></ref><ref id="CIT0069"><label>69</label><element-citation publication-type="book"><collab>Vector-borne Disease Control Programme</collab><article-title>Annual malaria report</article-title><year>2006</year><publisher-loc>Thimphu, Bhutan</publisher-loc><publisher-name>VBDCP, Ministry of Health</publisher-name></element-citation></ref><ref id="CIT0070"><label>70</label><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Konradsen</surname><given-names>F</given-names></name><name><surname>Amerasinghe</surname><given-names>FP</given-names></name><name><surname>van der Hoek</surname><given-names>W</given-names></name><name><surname>Amerasinghe</surname><given-names>PH</given-names></name></person-group><article-title>Malaria in Sri Lanka, current knowledge on transmission and control</article-title><year>2000</year><publisher-loc>Battaramulla, Sri Lanka</publisher-loc><publisher-name>International Water Management Institute</publisher-name></element-citation></ref><ref id="CIT0071"><label>71</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Silva</surname><given-names>KT</given-names></name></person-group><article-title>“Public health” for whose benefit? Multiple discourses on malaria in Sri Lanka</article-title><source>Med Anthropol</source><year>1997</year><volume>17</volume><fpage>195</fpage><lpage>214</lpage><pub-id pub-id-type="pmid">9311223</pub-id></element-citation></ref><ref id="CIT0072"><label>72</label><element-citation publication-type="webpage"><collab>UNICEF</collab><source>Malaria</source><year>2013</year><comment>UNICEF. Available from: <ext-link ext-link-type="uri" xlink:href="http://www.unicef.org/health/index_malaria.html">http://www.unicef.org/health/index_malaria.html</ext-link> [cited 2 April 2016]</comment></element-citation></ref><ref id="CIT0073"><label>73</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Spencer</surname><given-names>S</given-names></name><name><surname>Grant</surname><given-names>AD</given-names></name><name><surname>Piola</surname><given-names>P</given-names></name><name><surname>Tukpo</surname><given-names>K</given-names></name><name><surname>Okia</surname><given-names>M</given-names></name><name><surname>Gracia</surname><given-names>M</given-names></name><etal></etal></person-group><article-title>Malaria in camps for internally-displaced persons in Uganda: evaluation of an insecticide treated bednet distribution programme</article-title><source>Trans R Soc Trop Med Hyg</source><year>2004</year><volume>98</volume><fpage>719</fpage><lpage>27</lpage><pub-id pub-id-type="pmid">15485702</pub-id></element-citation></ref><ref id="CIT0074"><label>74</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tekelehaimanot</surname><given-names>A</given-names></name><name><surname>Sachs</surname><given-names>JD</given-names></name><name><surname>Curtis</surname><given-names>C</given-names></name></person-group><article-title>Malaria control needs mass distribution of insecticidal bednets</article-title><source>Lancet</source><year>2007</year><volume>369</volume><fpage>2143</fpage><lpage>6</lpage><pub-id pub-id-type="pmid">17597200</pub-id></element-citation></ref><ref id="CIT0075"><label>75</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Curtis</surname><given-names>C</given-names></name><name><surname>Maxwell</surname><given-names>C</given-names></name><name><surname>Leminge</surname><given-names>M</given-names></name><name><surname>Kilama</surname><given-names>WL</given-names></name><name><surname>Steketee</surname><given-names>RW</given-names></name><name><surname>Hawley</surname><given-names>WA</given-names></name><etal></etal></person-group><article-title>Scaling up coverage with insecticide-treated nets against malaria in Africa: who should pay?</article-title><source>Lancet Infect Dis</source><year>2003</year><volume>3</volume><fpage>304</fpage><lpage>7</lpage><pub-id pub-id-type="pmid">12726981</pub-id></element-citation></ref><ref id="CIT0076"><label>76</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Noor</surname><given-names>AM</given-names></name><name><surname>Mutheu</surname><given-names>JJ</given-names></name><name><surname>Tatem</surname><given-names>AJ</given-names></name><name><surname>Hay</surname><given-names>SI</given-names></name><name><surname>Snow</surname><given-names>RW</given-names></name></person-group><article-title>Insecticide-treated net coverage in Africa: mapping progress in 2000–07</article-title><source>Lancet</source><year>2009</year><volume>373</volume><fpage>58</fpage><lpage>67</lpage><pub-id pub-id-type="pmid">19019422</pub-id></element-citation></ref><ref id="CIT0077"><label>77</label><element-citation publication-type="book"><collab>RBM Partnership</collab><article-title>The Global Malaria Action Plan: for a malaria-free world</article-title><year>2008</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="CIT0078"><label>78</label><element-citation publication-type="book"><collab>RBM Partnership Secretariat</collab><article-title>RBM global strategy 2005–2015</article-title><year>2005</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="CIT0079"><label>79</label><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Hill</surname><given-names>J</given-names></name><name><surname>Lines</surname><given-names>J</given-names></name><name><surname>Rowland</surname><given-names>M</given-names></name></person-group><article-title>Insecticide-treated nets</article-title><source>Adv Parasitol</source><year>2006</year><volume>61</volume><fpage>77</fpage><lpage>128</lpage><pub-id pub-id-type="pmid">16735163</pub-id></element-citation></ref><ref id="CIT0080"><label>80</label><element-citation publication-type="book"><collab>World Health Organization</collab><article-title>Guidelines for the treatment of malaria</article-title><year>2015</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="CIT0081"><label>81</label><element-citation publication-type="book"><collab>National Vector Borne Disease Control Programme, National Institute of Malaria Research</collab><source>Guidelines for diagnosis and treatment of malaria in India</source><year>2009</year><publisher-loc>India</publisher-loc><publisher-name>Government of India</publisher-name><comment>Available from: <ext-link ext-link-type="uri" xlink:href="http://www.nvbdcp.gov.in/Doc/Guidelines-Diagnosis-Treatment-Mal-2009.pdf">http://www.nvbdcp.gov.in/Doc/Guidelines-Diagnosis-Treatment-Mal-2009.pdf</ext-link> [cited 2 April 2016]</comment></element-citation></ref></ref-list></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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