Le SIDA en Afrique subsaharienne (serveur d'exploration)

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Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study

Identifieur interne : 000463 ( PascalFrancis/Corpus ); précédent : 000462; suivant : 000464

Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study

Auteurs : Laura K. Murray ; Katherine Semrau ; Ellen Mccurley ; Donald M. Thea ; Nancy Scott ; Mwiya Mwiya ; Chipepo Kankasa ; Judith Bass ; Paul Bolton

Source :

RBID : Pascal:09-0176016

Descripteurs français

English descriptors

Abstract

Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
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A03   1    @0 AIDS Care : (Print)
A05       @2 21
A06       @2 1
A08 01  1  ENG  @1 Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study
A11 01  1    @1 MURRAY (Laura K.)
A11 02  1    @1 SEMRAU (Katherine)
A11 03  1    @1 MCCURLEY (Ellen)
A11 04  1    @1 THEA (Donald M.)
A11 05  1    @1 SCOTT (Nancy)
A11 06  1    @1 MWIYA (Mwiya)
A11 07  1    @1 KANKASA (Chipepo)
A11 08  1    @1 BASS (Judith)
A11 09  1    @1 BOLTON (Paul)
A14 01      @1 Center for International Health and Development, Boston University School of Public Health @2 Boston @3 USA @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut.
A14 02      @1 The Pendulam Project @3 INC @Z 3 aut.
A14 03      @1 University Teaching Hospital @2 Lusaka @3 ZMB @Z 6 aut. @Z 7 aut.
A14 04      @1 Johns Hopkins University, School of Public Health @2 Baltimore, MD @3 USA @Z 8 aut. @Z 9 aut.
A20       @1 78-86
A21       @1 2009
A23 01      @0 ENG
A43 01      @1 INIST @2 22096 @5 354000184082610110
A44       @0 0000 @1 © 2009 INIST-CNRS. All rights reserved.
A45       @0 1 p.1/4
A47 01  1    @0 09-0176016
A60       @1 P
A61       @0 A
A64 01  1    @0 AIDS Care : (Print)
A66 01      @0 GBR
C01 01    ENG  @0 Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels.
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C03 11  X  FRE  @0 Homme @5 19
C03 11  X  ENG  @0 Human @5 19
C03 11  X  SPA  @0 Hombre @5 19
C03 12  X  FRE  @0 Femme @5 20
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C07 05  X  SPA  @0 Contexto social @5 38
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C07 06  X  SPA  @0 Inmunodeficiencia @5 39
C07 07  X  FRE  @0 Immunopathologie @5 41
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N21       @1 131

Format Inist (serveur)

NO : PASCAL 09-0176016 INIST
ET : Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study
AU : MURRAY (Laura K.); SEMRAU (Katherine); MCCURLEY (Ellen); THEA (Donald M.); SCOTT (Nancy); MWIYA (Mwiya); KANKASA (Chipepo); BASS (Judith); BOLTON (Paul)
AF : Center for International Health and Development, Boston University School of Public Health/Boston/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.); The Pendulam Project/Inconnu (3 aut.); University Teaching Hospital/Lusaka/Zambie (6 aut., 7 aut.); Johns Hopkins University, School of Public Health/Baltimore, MD/Etats-Unis (8 aut., 9 aut.)
DT : Publication en série; Niveau analytique
SO : AIDS Care : (Print); ISSN 0954-0121; Royaume-Uni; Da. 2009; Vol. 21; No. 1; Pp. 78-86; Bibl. 1 p.1/4
LA : Anglais
EA : Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels.
CC : 002B02S05; 002A26N03A
FD : Observance médicamenteuse; Pharmacothérapie; Antirétroviral; Milieu urbain; Analyse qualitative; SIDA; Santé publique; Zambie; Facteur prédictif; Prise de décision; Homme; Femme; Antiviral; Acceptabilité
FG : Traitement; Virose; Infection; Afrique; Environnement social; Immunodéficit; Immunopathologie
ED : Drug compliance; Pharmacotherapy; Antiretroviral agent; Urban environment; Qualitative analysis; AIDS; Public health; Zambia; Predictive factor; Decision making; Human; Woman; Antiviral
EG : Treatment; Viral disease; Infection; Africa; Social environment; Immune deficiency; Immunopathology
SD : Observancia de la medicación; Farmacoterapia; Antiretroviral; Medio urbano; Análisis cualitativo; SIDA; Salud pública; Zambia; Factor predictivo; Toma decision; Hombre; Mujer; Antiviral
LO : INIST-22096.354000184082610110
ID : 09-0176016

Links to Exploration step

Pascal:09-0176016

Le document en format XML

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<div type="abstract" xml:lang="en">Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels.</div>
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<ET>Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study</ET>
<AU>MURRAY (Laura K.); SEMRAU (Katherine); MCCURLEY (Ellen); THEA (Donald M.); SCOTT (Nancy); MWIYA (Mwiya); KANKASA (Chipepo); BASS (Judith); BOLTON (Paul)</AU>
<AF>Center for International Health and Development, Boston University School of Public Health/Boston/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.); The Pendulam Project/Inconnu (3 aut.); University Teaching Hospital/Lusaka/Zambie (6 aut., 7 aut.); Johns Hopkins University, School of Public Health/Baltimore, MD/Etats-Unis (8 aut., 9 aut.)</AF>
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<EA>Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels.</EA>
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<FD>Observance médicamenteuse; Pharmacothérapie; Antirétroviral; Milieu urbain; Analyse qualitative; SIDA; Santé publique; Zambie; Facteur prédictif; Prise de décision; Homme; Femme; Antiviral; Acceptabilité</FD>
<FG>Traitement; Virose; Infection; Afrique; Environnement social; Immunodéficit; Immunopathologie</FG>
<ED>Drug compliance; Pharmacotherapy; Antiretroviral agent; Urban environment; Qualitative analysis; AIDS; Public health; Zambia; Predictive factor; Decision making; Human; Woman; Antiviral</ED>
<EG>Treatment; Viral disease; Infection; Africa; Social environment; Immune deficiency; Immunopathology</EG>
<SD>Observancia de la medicación; Farmacoterapia; Antiretroviral; Medio urbano; Análisis cualitativo; SIDA; Salud pública; Zambia; Factor predictivo; Toma decision; Hombre; Mujer; Antiviral</SD>
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