Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study
Identifieur interne : 000463 ( PascalFrancis/Corpus ); précédent : 000462; suivant : 000464Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study
Auteurs : Laura K. Murray ; Katherine Semrau ; Ellen Mccurley ; Donald M. Thea ; Nancy Scott ; Mwiya Mwiya ; Chipepo Kankasa ; Judith Bass ; Paul BoltonSource :
- AIDS Care : (Print) [ 0954-0121 ] ; 2009.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels.
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Format Inist (serveur)
NO : | PASCAL 09-0176016 INIST |
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ET : | Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study |
AU : | MURRAY (Laura K.); SEMRAU (Katherine); MCCURLEY (Ellen); THEA (Donald M.); SCOTT (Nancy); MWIYA (Mwiya); KANKASA (Chipepo); BASS (Judith); BOLTON (Paul) |
AF : | Center for International Health and Development, Boston University School of Public Health/Boston/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.); The Pendulam Project/Inconnu (3 aut.); University Teaching Hospital/Lusaka/Zambie (6 aut., 7 aut.); Johns Hopkins University, School of Public Health/Baltimore, MD/Etats-Unis (8 aut., 9 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | AIDS Care : (Print); ISSN 0954-0121; Royaume-Uni; Da. 2009; Vol. 21; No. 1; Pp. 78-86; Bibl. 1 p.1/4 |
LA : | Anglais |
EA : | Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels. |
CC : | 002B02S05; 002A26N03A |
FD : | Observance médicamenteuse; Pharmacothérapie; Antirétroviral; Milieu urbain; Analyse qualitative; SIDA; Santé publique; Zambie; Facteur prédictif; Prise de décision; Homme; Femme; Antiviral; Acceptabilité |
FG : | Traitement; Virose; Infection; Afrique; Environnement social; Immunodéficit; Immunopathologie |
ED : | Drug compliance; Pharmacotherapy; Antiretroviral agent; Urban environment; Qualitative analysis; AIDS; Public health; Zambia; Predictive factor; Decision making; Human; Woman; Antiviral |
EG : | Treatment; Viral disease; Infection; Africa; Social environment; Immune deficiency; Immunopathology |
SD : | Observancia de la medicación; Farmacoterapia; Antiretroviral; Medio urbano; Análisis cualitativo; SIDA; Salud pública; Zambia; Factor predictivo; Toma decision; Hombre; Mujer; Antiviral |
LO : | INIST-22096.354000184082610110 |
ID : | 09-0176016 |
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Pascal:09-0176016Le document en format XML
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<front><div type="abstract" xml:lang="en">Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels.</div>
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<fC03 i1="06" i2="X" l="ENG"><s0>AIDS</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>SIDA</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Santé publique</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Public health</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Salud pública</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Zambie</s0>
<s2>NG</s2>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Zambia</s0>
<s2>NG</s2>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Zambia</s0>
<s2>NG</s2>
<s5>08</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Facteur prédictif</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Predictive factor</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Factor predictivo</s0>
<s5>09</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Prise de décision</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Decision making</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Toma decision</s0>
<s5>10</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Homme</s0>
<s5>19</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Human</s0>
<s5>19</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Hombre</s0>
<s5>19</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Femme</s0>
<s5>20</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Woman</s0>
<s5>20</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Mujer</s0>
<s5>20</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>Antiviral</s0>
<s5>31</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG"><s0>Antiviral</s0>
<s5>31</s5>
</fC03>
<fC03 i1="13" i2="X" l="SPA"><s0>Antiviral</s0>
<s5>31</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE"><s0>Acceptabilité</s0>
<s4>INC</s4>
<s5>86</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Traitement</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Treatment</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Tratamiento</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Virose</s0>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Viral disease</s0>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Virosis</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Infection</s0>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Infection</s0>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Afrique</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Africa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Africa</s0>
<s2>NG</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Environnement social</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Social environment</s0>
<s5>38</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Contexto social</s0>
<s5>38</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Immunodéficit</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Immune deficiency</s0>
<s5>39</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Inmunodeficiencia</s0>
<s5>39</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>41</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>41</s5>
</fC07>
<fN21><s1>131</s1>
</fN21>
</pA>
</standard>
<server><NO>PASCAL 09-0176016 INIST</NO>
<ET>Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women : a qualitative study</ET>
<AU>MURRAY (Laura K.); SEMRAU (Katherine); MCCURLEY (Ellen); THEA (Donald M.); SCOTT (Nancy); MWIYA (Mwiya); KANKASA (Chipepo); BASS (Judith); BOLTON (Paul)</AU>
<AF>Center for International Health and Development, Boston University School of Public Health/Boston/Etats-Unis (1 aut., 2 aut., 3 aut., 4 aut., 5 aut.); The Pendulam Project/Inconnu (3 aut.); University Teaching Hospital/Lusaka/Zambie (6 aut., 7 aut.); Johns Hopkins University, School of Public Health/Baltimore, MD/Etats-Unis (8 aut., 9 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>AIDS Care : (Print); ISSN 0954-0121; Royaume-Uni; Da. 2009; Vol. 21; No. 1; Pp. 78-86; Bibl. 1 p.1/4</SO>
<LA>Anglais</LA>
<EA>Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors affecting HIV-infected women's decision to accept or continue with ART. Some of the barriers identified by this study are consistent with factors cited in the existing adherence literature from both developed and developing nations such as side effects, hunger and stigma; other factors have not been previously reported. One major theme was unfamiliarity with the implications of having a chronic, potentially deadly disease. Other emerging themes from this study include the complicated effect of ART on interpersonal relationship, particularly between husbands and wives, the presence of depression and hopelessness, and lack of accurate information. The results suggest that the reasons for non-uptake of treatment include issues related to local cultural frameworks (e.g., illness ideology), mental and behavioral health (e.g., depression and/or interpersonal challenges), stigma, and motivating factors (e.g., values of church or marriage) of different cultures that affect the ability and willingness to take life-saving medicine for a long period of time. Qualitative studies are critical to better understand why ART eligible individuals are choosing not to initiate or continue treatment to achieve needed adherence levels.</EA>
<CC>002B02S05; 002A26N03A</CC>
<FD>Observance médicamenteuse; Pharmacothérapie; Antirétroviral; Milieu urbain; Analyse qualitative; SIDA; Santé publique; Zambie; Facteur prédictif; Prise de décision; Homme; Femme; Antiviral; Acceptabilité</FD>
<FG>Traitement; Virose; Infection; Afrique; Environnement social; Immunodéficit; Immunopathologie</FG>
<ED>Drug compliance; Pharmacotherapy; Antiretroviral agent; Urban environment; Qualitative analysis; AIDS; Public health; Zambia; Predictive factor; Decision making; Human; Woman; Antiviral</ED>
<EG>Treatment; Viral disease; Infection; Africa; Social environment; Immune deficiency; Immunopathology</EG>
<SD>Observancia de la medicación; Farmacoterapia; Antiretroviral; Medio urbano; Análisis cualitativo; SIDA; Salud pública; Zambia; Factor predictivo; Toma decision; Hombre; Mujer; Antiviral</SD>
<LO>INIST-22096.354000184082610110</LO>
<ID>09-0176016</ID>
</server>
</inist>
</record>
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