Prevalence and factors associated with tuberculosis treatment outcome among hazardous or harmful alcohol users in public primary health care in South Africa
Identifieur interne : 003121 ( Ncbi/Curation ); précédent : 003120; suivant : 003122Prevalence and factors associated with tuberculosis treatment outcome among hazardous or harmful alcohol users in public primary health care in South Africa
Auteurs : K. Peltzer [Afrique du Sud] ; Js Louw [Thaïlande]Source :
- African Health Sciences [ 1680-6905 ] ; 2014.
Abstract
Tuberculosis (TB) remains a chronic infectious disease with high morbidity and mortality.
The aim of this study was to assess the prevalence and associated factors of tuberculosis treatment failure, death and default among hazardous or harmful alcohol users.
We conducted a prospective study with TB patients in 40 public health clinics in three districts in South Africa. All consecutively new tuberculosis and retreatment patients presenting at the 40 primary health care facilities with hazardous or harmful alcohol use were included in this study. Logistic regression was used to assess determinants of TB treatment failure, death and default.
The findings of our study showed that 70% of TB patients were either cured or had completed their TB treatment by the end of 6 months. In multivariate analysis participants living in a shack or traditional housing (Odds Ratio=OR: 0.63, Confidence Interval=CI: 0.45–0.89), being a TB retreatment patient (OR: 1.61, CI: 1.15–2.26) and residing in the eThekwini district (OR: 1.82, CI: 1.27–2.58) were significant predictors of treatment failure, death and default.
A high rate of treatment failure, death and default were found in the TB patients. Several factors were identified that can guide interventions for the prevention of treatment failure, death and default.
Url:
DOI: 10.4314/ahs.v14i1.24
PubMed: 26060473
PubMed Central: 4449054
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Peltzer</name><affiliation wicri:level="1"><nlm:aff id="A1">HIV/AIDS, TB and STI (HAST) Research Programme, Human Sciences Research Council, Pretoria and Durban, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>HIV/AIDS, TB and STI (HAST) Research Programme, Human Sciences Research Council, Pretoria and Durban</wicri:regionArea><wicri:noRegion>Pretoria and Durban</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2"> Department of Psychology, University of Limpopo, Turfloop, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Department of Psychology, University of Limpopo, Turfloop</wicri:regionArea><wicri:noRegion>Turfloop</wicri:noRegion></affiliation></author><author><name sortKey="Louw, Js" sort="Louw, Js" uniqKey="Louw J" first="Js" last="Louw">Js Louw</name><affiliation wicri:level="1"><nlm:aff id="A3"> ASEAN Institute for Health Development, Mahidol University, Salaya, Thailand</nlm:aff><country xml:lang="fr">Thaïlande</country><wicri:regionArea> ASEAN Institute for Health Development, Mahidol University, Salaya</wicri:regionArea><wicri:noRegion>Salaya</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26060473</idno><idno type="pmc">4449054</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449054</idno><idno type="RBID">PMC:4449054</idno><idno type="doi">10.4314/ahs.v14i1.24</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000024</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000024</idno><idno type="wicri:Area/Pmc/Curation">000024</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000024</idno><idno type="wicri:Area/Pmc/Checkpoint">001164</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001164</idno><idno type="wicri:Area/Ncbi/Merge">003121</idno><idno type="wicri:Area/Ncbi/Curation">003121</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Prevalence and factors associated with tuberculosis treatment outcome among hazardous or harmful alcohol users in public primary health care in South Africa</title><author><name sortKey="Peltzer, K" sort="Peltzer, K" uniqKey="Peltzer K" first="K" last="Peltzer">K. Peltzer</name><affiliation wicri:level="1"><nlm:aff id="A1">HIV/AIDS, TB and STI (HAST) Research Programme, Human Sciences Research Council, Pretoria and Durban, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>HIV/AIDS, TB and STI (HAST) Research Programme, Human Sciences Research Council, Pretoria and Durban</wicri:regionArea><wicri:noRegion>Pretoria and Durban</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A2"> Department of Psychology, University of Limpopo, Turfloop, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Department of Psychology, University of Limpopo, Turfloop</wicri:regionArea><wicri:noRegion>Turfloop</wicri:noRegion></affiliation></author><author><name sortKey="Louw, Js" sort="Louw, Js" uniqKey="Louw J" first="Js" last="Louw">Js Louw</name><affiliation wicri:level="1"><nlm:aff id="A3"> ASEAN Institute for Health Development, Mahidol University, Salaya, Thailand</nlm:aff><country xml:lang="fr">Thaïlande</country><wicri:regionArea> ASEAN Institute for Health Development, Mahidol University, Salaya</wicri:regionArea><wicri:noRegion>Salaya</wicri:noRegion></affiliation></author></analytic><series><title level="j">African Health Sciences</title><idno type="ISSN">1680-6905</idno><idno type="eISSN">1729-0503</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>Tuberculosis (TB) remains a chronic infectious disease with high morbidity and mortality.</p></sec><sec><title>Objective</title><p>The aim of this study was to assess the prevalence and associated factors of tuberculosis treatment failure, death and default among hazardous or harmful alcohol users.</p></sec><sec sec-type="methods"><title>Method</title><p>We conducted a prospective study with TB patients in 40 public health clinics in three districts in South Africa. All consecutively new tuberculosis and retreatment patients presenting at the 40 primary health care facilities with hazardous or harmful alcohol use were included in this study. Logistic regression was used to assess determinants of TB treatment failure, death and default.</p></sec><sec sec-type="results"><title>Results</title><p>The findings of our study showed that 70% of TB patients were either cured or had completed their TB treatment by the end of 6 months. In multivariate analysis participants living in a shack or traditional housing (Odds Ratio=OR: 0.63, Confidence Interval=CI: 0.45–0.89), being a TB retreatment patient (OR: 1.61, CI: 1.15–2.26) and residing in the eThekwini district (OR: 1.82, CI: 1.27–2.58) were significant predictors of treatment failure, death and default.</p></sec><sec sec-type="conclusions"><title>Conclusion</title><p>A high rate of treatment failure, death and default were found in the TB patients. Several factors were identified that can guide interventions for the prevention of treatment failure, death and default.</p></sec></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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