Challenges in PMTCT antiretroviral adherence in northern KwaZulu-Natal, South Africa.
Identifieur interne : 001144 ( Ncbi/Curation ); précédent : 001143; suivant : 001145Challenges in PMTCT antiretroviral adherence in northern KwaZulu-Natal, South Africa.
Auteurs : S. Mepham [Afrique du Sud] ; Z. Zondi ; A. Mbuyazi ; N. Mkhwanazi ; M L NewellSource :
- AIDS care [ 1360-0451 ] ; 2011.
Descripteurs français
- KwdFr :
- Adulte, Antirétroviraux, Connaissances, attitudes et pratiques en santé, Enquêtes et questionnaires, Facteurs socioéconomiques, Femelle, Grossesse, Humains, Infections à VIH (ethnologie), Infections à VIH (traitement médicamenteux), Infections à VIH (transmission), Infections à VIH (épidémiologie), Observance du traitement médicamenteux (), Observance du traitement médicamenteux (ethnologie), Population d'origine africaine (ethnologie), Prophylaxie après exposition, République d'Afrique du Sud (épidémiologie), Transmission verticale de maladie infectieuse (), VIH-1 (Virus de l'Immunodéficience Humaine de type 1).
- MESH :
- ethnologie : Infections à VIH, Observance du traitement médicamenteux, Population d'origine africaine.
- traitement médicamenteux : Infections à VIH.
- épidémiologie : Infections à VIH, République d'Afrique du Sud.
- Adulte, Antirétroviraux, Connaissances, attitudes et pratiques en santé, Enquêtes et questionnaires, Facteurs socioéconomiques, Femelle, Grossesse, Humains, Observance du traitement médicamenteux, Prophylaxie après exposition, Transmission verticale de maladie infectieuse, VIH-1 (Virus de l'Immunodéficience Humaine de type 1).
- Wicri :
- geographic : Afrique du Sud.
English descriptors
- KwdEn :
- Adult, African Continental Ancestry Group (ethnology), Anti-Retroviral Agents, Female, HIV Infections (drug therapy), HIV Infections (epidemiology), HIV Infections (ethnology), HIV Infections (transmission), HIV-1, Health Knowledge, Attitudes, Practice, Humans, Infectious Disease Transmission, Vertical (prevention & control), Infectious Disease Transmission, Vertical (statistics & numerical data), Medication Adherence (ethnology), Medication Adherence (statistics & numerical data), Post-Exposure Prophylaxis, Pregnancy, Socioeconomic Factors, South Africa (epidemiology), Surveys and Questionnaires.
- MESH :
- chemical : Anti-Retroviral Agents.
- geographic , epidemiology : South Africa.
- drug therapy : HIV Infections.
- epidemiology : HIV Infections.
- ethnology : African Continental Ancestry Group, HIV Infections, Medication Adherence.
- prevention & control : Infectious Disease Transmission, Vertical.
- statistics & numerical data : Infectious Disease Transmission, Vertical, Medication Adherence.
- transmission : HIV Infections.
- Adult, Female, HIV-1, Health Knowledge, Attitudes, Practice, Humans, Post-Exposure Prophylaxis, Pregnancy, Socioeconomic Factors, Surveys and Questionnaires.
Abstract
Women living with HIV in sub-Saharan Africa face significant challenges in accessing HIV care and adhering to antiretroviral therapy. Most reports have focused on issues relating to long-term adherence such as those surrounding stigma and disclosure, hunger, cultural factors, lack of accurate health information, lack of social support, medication side effects and overcrowded health systems. Information related to the challenges facing pregnant women when taking antiretrovirals for prophylactic purposes is limited. The "Kesho Bora Study" is a multicentre prevention of mother-to-child transmission (PMTCT) trial in sub-Saharan Africa evaluating the PMTCT efficacy of triple therapy until cessation of breast feeding compared to short course zidovudine monotherapy in a predominantly breast feeding population. Following unexplained discrepancies during objective adherence assessments, a sub-study was conducted at one site to examine the underlying adherence issues.
DOI: 10.1080/09540121.2010.516341
PubMed: 21293987
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pubmed:21293987Le document en format XML
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<term>Grossesse</term>
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<term>Observance du traitement médicamenteux</term>
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<front><div type="abstract" xml:lang="en">Women living with HIV in sub-Saharan Africa face significant challenges in accessing HIV care and adhering to antiretroviral therapy. Most reports have focused on issues relating to long-term adherence such as those surrounding stigma and disclosure, hunger, cultural factors, lack of accurate health information, lack of social support, medication side effects and overcrowded health systems. Information related to the challenges facing pregnant women when taking antiretrovirals for prophylactic purposes is limited. The "Kesho Bora Study" is a multicentre prevention of mother-to-child transmission (PMTCT) trial in sub-Saharan Africa evaluating the PMTCT efficacy of triple therapy until cessation of breast feeding compared to short course zidovudine monotherapy in a predominantly breast feeding population. Following unexplained discrepancies during objective adherence assessments, a sub-study was conducted at one site to examine the underlying adherence issues.</div>
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