Management of Chlamydia trachomatis genital tract infection: screening and treatment challenges
Identifieur interne : 003C61 ( Main/Exploration ); précédent : 003C60; suivant : 003C62Management of Chlamydia trachomatis genital tract infection: screening and treatment challenges
Auteurs : Brandie D. Taylor ; Catherine L. HaggertySource :
- Infection and drug resistance [ 1178-6973 ] ; 2011.
Abstract
Url:
DOI: 10.2147/IDR.S12715
PubMed: 21694906
PubMed Central: 3108753
Affiliations:
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Le document en format XML
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genital tract infection: screening and treatment challenges</title>
<author><name sortKey="Taylor, Brandie D" sort="Taylor, Brandie D" uniqKey="Taylor B" first="Brandie D" last="Taylor">Brandie D. Taylor</name>
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<author><name sortKey="Haggerty, Catherine L" sort="Haggerty, Catherine L" uniqKey="Haggerty C" first="Catherine L" last="Haggerty">Catherine L. Haggerty</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Management of <italic>Chlamydia trachomatis</italic>
genital tract infection: screening and treatment challenges</title>
<author><name sortKey="Taylor, Brandie D" sort="Taylor, Brandie D" uniqKey="Taylor B" first="Brandie D" last="Taylor">Brandie D. Taylor</name>
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<author><name sortKey="Haggerty, Catherine L" sort="Haggerty, Catherine L" uniqKey="Haggerty C" first="Catherine L" last="Haggerty">Catherine L. Haggerty</name>
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<series><title level="j">Infection and drug resistance</title>
<idno type="eISSN">1178-6973</idno>
<imprint><date when="2011">2011</date>
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<front><div type="abstract" xml:lang="en"><p><italic>Chlamydia trachomatis</italic>
is a prevalent sexually transmitted infection that can lead to serious reproductive morbidity. Management and control of <italic>C. trachomatis</italic>
is a challenge, largely due to its asymptomatic nature and our incomplete understanding of its natural history. Although chlamydia screening programs have been implemented worldwide, several countries have observed increasing rates of reported chlamydia cases. We reviewed the literature relating to the long-term complications of <italic>C. trachomatis</italic>
, as well as screening strategies, treatment, and prevention strategies for reducing chlamydia in the population. Articles from 1950–2010 were identified through a Medline search using the keyword “<italic>Chlamydia trachomatis</italic>
” combined with “screening”, “pelvic inflammatory disease”, “endometritis”, “salpingitis”, “infertility”, “ectopic pregnancy”, “urethritis”, “epididymitis”, “proctitis”, “prostatitis”, “reinfection”, “cost-effectiveness”, “treatment”, “vaccines”, or “prevention”. Progression of <italic>C. trachomatis</italic>
varies, and recurrent infections are common. Currently, there is limited evidence on the effectiveness of chlamydia screening. Higher quality studies are needed to determine the efficacy of more frequent screening, on a broader range of sequelae, including infertility and ectopic pregnancy, in addition to pelvic inflammatory disease. Studies should focus on delineating the natural history of recurrent infections, paying particular attention to treatment failures. Furthermore, alternatives to screening, such as vaccines, should continue to be explored.</p>
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<tree><noCountry><name sortKey="Haggerty, Catherine L" sort="Haggerty, Catherine L" uniqKey="Haggerty C" first="Catherine L" last="Haggerty">Catherine L. Haggerty</name>
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