Determinants of Survival in Adult HIV Clients on Antiretroviral Therapy in Lawra and Jirapa Districts of Upper West Region, Ghana.
Identifieur interne : 00A109 ( Main/Exploration ); précédent : 00A108; suivant : 00A110Determinants of Survival in Adult HIV Clients on Antiretroviral Therapy in Lawra and Jirapa Districts of Upper West Region, Ghana.
Auteurs : Gabriel Asare Okyere [Royaume-Uni] ; Paul Awinbil Alalbil [Ghana] ; Henry Ping-Naah [Ghana] ; Yakubu Tifere [Ghana]Source :
- Journal of the International Association of Providers of AIDS Care [ 2325-9574 ]
Descripteurs français
- KwdFr :
- MESH :
- mortalité : Infections à VIH.
- traitement médicamenteux : Infections à VIH.
- usage thérapeutique : Agents antiVIH.
- Adulte, Adulte d'âge moyen, Analyse de survie, Estimation de Kaplan-Meier, Femelle, Ghana, Humains, Jeune adulte, Mâle, Études de cohortes, Études de suivi, Études rétrospectives.
- Wicri :
- geographic : Ghana.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Anti-HIV Agents.
- geographic : Ghana.
- drug therapy : HIV Infections.
- mortality : HIV Infections.
- Adult, Cohort Studies, Female, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Retrospective Studies, Survival Analysis, Young Adult.
Abstract
We describe the rate of death and identify the determinants of survival in a cohort of adults starting antiretroviral therapy (ART) in 2 hospitals in Upper West Region, Ghana. Kaplan-Meier model was used to estimate the survival probability after ART initiation and Cox proportional hazard model used to assess the relationship between baseline variables and mortality. A total of 91 clients who were initiated on ART in both hospitals participated in the study. Clients staged in the World Health Organization (WHO) clinical stage III/IV had a higher risk of mortality than those staging I/II (hazard ratio [HR] of 3.93). Hemoglobin value at baseline with a cutoff ≥12 g/dL for women (and ≥13 for men) was strongly associated with mortality in participants with an HR of 3.87 (95% confidence interval [CI]: 0.71-21.19) for severe anemia, 2.11 (95% CI: 0.45-9.93) for moderate anemia, and 0.88 (95% CI: 0.16-4.82) for mild anemia. Anemia and WHO staging were independent predictors of mortality.
DOI: 10.1177/2325957413500531
PubMed: 24344253
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001059
- to stream PubMed, to step Curation: 001059
- to stream PubMed, to step Checkpoint: 001059
- to stream Ncbi, to step Merge: 002593
- to stream Ncbi, to step Curation: 002593
- to stream Ncbi, to step Checkpoint: 002593
- to stream Main, to step Merge: 00A363
- to stream Main, to step Curation: 00A109
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Determinants of Survival in Adult HIV Clients on Antiretroviral Therapy in Lawra and Jirapa Districts of Upper West Region, Ghana.</title><author><name sortKey="Okyere, Gabriel Asare" sort="Okyere, Gabriel Asare" uniqKey="Okyere G" first="Gabriel Asare" last="Okyere">Gabriel Asare Okyere</name><affiliation wicri:level="1"><nlm:affiliation>Department of Statistics, Western Michigan University, Kalamazoo, MI, USA goasare@yahoo.co.uk.</nlm:affiliation><country wicri:rule="url">Royaume-Uni</country><wicri:regionArea>Department of Statistics, Western Michigan University, Kalamazoo, MI</wicri:regionArea><wicri:noRegion>MI</wicri:noRegion></affiliation></author><author><name sortKey="Alalbil, Paul Awinbil" sort="Alalbil, Paul Awinbil" uniqKey="Alalbil P" first="Paul Awinbil" last="Alalbil">Paul Awinbil Alalbil</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Ping Naah, Henry" sort="Ping Naah, Henry" uniqKey="Ping Naah H" first="Henry" last="Ping-Naah">Henry Ping-Naah</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Tifere, Yakubu" sort="Tifere, Yakubu" uniqKey="Tifere Y" first="Yakubu" last="Tifere">Yakubu Tifere</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2015 May-Jun</MedlineDate></PubDate></date><idno type="RBID">pubmed:24344253</idno><idno type="pmid">24344253</idno><idno type="doi">10.1177/2325957413500531</idno><idno type="wicri:Area/PubMed/Corpus">001059</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001059</idno><idno type="wicri:Area/PubMed/Curation">001059</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001059</idno><idno type="wicri:Area/PubMed/Checkpoint">001059</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001059</idno><idno type="wicri:Area/Ncbi/Merge">002593</idno><idno type="wicri:Area/Ncbi/Curation">002593</idno><idno type="wicri:Area/Ncbi/Checkpoint">002593</idno><idno type="wicri:doubleKey">2325-9574::Okyere G:determinants:of:survival</idno><idno type="wicri:Area/Main/Merge">00A363</idno><idno type="wicri:Area/Main/Curation">00A109</idno><idno type="wicri:Area/Main/Exploration">00A109</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Determinants of Survival in Adult HIV Clients on Antiretroviral Therapy in Lawra and Jirapa Districts of Upper West Region, Ghana.</title><author><name sortKey="Okyere, Gabriel Asare" sort="Okyere, Gabriel Asare" uniqKey="Okyere G" first="Gabriel Asare" last="Okyere">Gabriel Asare Okyere</name><affiliation wicri:level="1"><nlm:affiliation>Department of Statistics, Western Michigan University, Kalamazoo, MI, USA goasare@yahoo.co.uk.</nlm:affiliation><country wicri:rule="url">Royaume-Uni</country><wicri:regionArea>Department of Statistics, Western Michigan University, Kalamazoo, MI</wicri:regionArea><wicri:noRegion>MI</wicri:noRegion></affiliation></author><author><name sortKey="Alalbil, Paul Awinbil" sort="Alalbil, Paul Awinbil" uniqKey="Alalbil P" first="Paul Awinbil" last="Alalbil">Paul Awinbil Alalbil</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Ping Naah, Henry" sort="Ping Naah, Henry" uniqKey="Ping Naah H" first="Henry" last="Ping-Naah">Henry Ping-Naah</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author><author><name sortKey="Tifere, Yakubu" sort="Tifere, Yakubu" uniqKey="Tifere Y" first="Yakubu" last="Tifere">Yakubu Tifere</name><affiliation wicri:level="1"><nlm:affiliation>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>Department of Mathematics, Kwame Nkrumah University of Science and Technology, Kumasi</wicri:regionArea><wicri:noRegion>Kumasi</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of the International Association of Providers of AIDS Care</title><idno type="ISSN">2325-9574</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Anti-HIV Agents (therapeutic use)</term><term>Cohort Studies</term><term>Female</term><term>Follow-Up Studies</term><term>Ghana</term><term>HIV Infections (drug therapy)</term><term>HIV Infections (mortality)</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Survival Analysis</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Agents antiVIH (usage thérapeutique)</term><term>Analyse de survie</term><term>Estimation de Kaplan-Meier</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Infections à VIH (mortalité)</term><term>Infections à VIH (traitement médicamenteux)</term><term>Jeune adulte</term><term>Mâle</term><term>Études de cohortes</term><term>Études de suivi</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-HIV Agents</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Ghana</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Agents antiVIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Cohort Studies</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Survival Analysis</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse de survie</term><term>Estimation de Kaplan-Meier</term><term>Femelle</term><term>Ghana</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Études de cohortes</term><term>Études de suivi</term><term>Études rétrospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Ghana</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We describe the rate of death and identify the determinants of survival in a cohort of adults starting antiretroviral therapy (ART) in 2 hospitals in Upper West Region, Ghana. Kaplan-Meier model was used to estimate the survival probability after ART initiation and Cox proportional hazard model used to assess the relationship between baseline variables and mortality. A total of 91 clients who were initiated on ART in both hospitals participated in the study. Clients staged in the World Health Organization (WHO) clinical stage III/IV had a higher risk of mortality than those staging I/II (hazard ratio [HR] of 3.93). Hemoglobin value at baseline with a cutoff ≥12 g/dL for women (and ≥13 for men) was strongly associated with mortality in participants with an HR of 3.87 (95% confidence interval [CI]: 0.71-21.19) for severe anemia, 2.11 (95% CI: 0.45-9.93) for moderate anemia, and 0.88 (95% CI: 0.16-4.82) for mild anemia. Anemia and WHO staging were independent predictors of mortality.</div></front></TEI><affiliations><list><country><li>Ghana</li><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Okyere, Gabriel Asare" sort="Okyere, Gabriel Asare" uniqKey="Okyere G" first="Gabriel Asare" last="Okyere">Gabriel Asare Okyere</name></noRegion></country><country name="Ghana"><noRegion><name sortKey="Alalbil, Paul Awinbil" sort="Alalbil, Paul Awinbil" uniqKey="Alalbil P" first="Paul Awinbil" last="Alalbil">Paul Awinbil Alalbil</name></noRegion><name sortKey="Ping Naah, Henry" sort="Ping Naah, Henry" uniqKey="Ping Naah H" first="Henry" last="Ping-Naah">Henry Ping-Naah</name><name sortKey="Tifere, Yakubu" sort="Tifere, Yakubu" uniqKey="Tifere Y" first="Yakubu" last="Tifere">Yakubu Tifere</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaSubSaharaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00A109 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00A109 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= SidaSubSaharaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:24344253
|texte= Determinants of Survival in Adult HIV Clients on Antiretroviral Therapy in Lawra and Jirapa Districts of Upper West Region, Ghana.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24344253" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SidaSubSaharaV1
| This area was generated with Dilib version V0.6.32. |  |