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Supplementary feeding in the care of the wasted HIV infected patient.

Identifieur interne : 004532 ( Main/Curation ); précédent : 004531; suivant : 004533

Supplementary feeding in the care of the wasted HIV infected patient.

Auteurs : Mark Manary ; Macdonald Ndekhat ; Joep J. Van Oosterhout

Source :

Malawi medical journal : the journal of Medical Association of Malawi [ 1995-7262 ] ; 2010.

RBID : pubmed:21614881

Descripteurs français

KwdFr :
- Adulte, Antirétroviraux (usage thérapeutique), Arachis, Charge virale, Femelle, Humains, Indice de masse corporelle, Infections à VIH (), Infections à VIH (traitement médicamenteux), Malawi, Mâle, Numération des lymphocytes CD4, Prise de poids, Produits alimentaires à base de soja, Qualité de vie, Résultat thérapeutique, Syndrome cachectique lié au VIH (diétothérapie), Syndrome cachectique lié au VIH (économie), Zea mays.
MESH :
- diétothérapie : Syndrome cachectique lié au VIH.
- traitement médicamenteux : Infections à VIH.
- usage thérapeutique : Antirétroviraux.
- économie : Syndrome cachectique lié au VIH.
- Adulte, Arachis, Charge virale, Femelle, Humains, Indice de masse corporelle, Infections à VIH, Malawi, Mâle, Numération des lymphocytes CD4, Prise de poids, Produits alimentaires à base de soja, Qualité de vie, Résultat thérapeutique, Zea mays.
Wicri :
- geographic : Malawi.

English descriptors

KwdEn :
- Adult, Anti-Retroviral Agents (therapeutic use), Arachis, Body Mass Index, CD4 Lymphocyte Count, Female, HIV Infections (complications), HIV Infections (drug therapy), HIV Wasting Syndrome (diet therapy), HIV Wasting Syndrome (economics), Humans, Malawi, Male, Quality of Life, Soy Foods, Treatment Outcome, Viral Load, Weight Gain, Zea mays.
MESH :
- chemical , therapeutic use : Anti-Retroviral Agents.
- geographic : Malawi.
- complications : HIV Infections.
- diet therapy : HIV Wasting Syndrome.
- drug therapy : HIV Infections.
- economics : HIV Wasting Syndrome.
- Adult, Arachis, Body Mass Index, CD4 Lymphocyte Count, Female, Humans, Male, Quality of Life, Soy Foods, Treatment Outcome, Viral Load, Weight Gain, Zea mays.

Abstract

Wasting and food insecurity are commonly seen in patients receiving antiretroviral treatment (ART) programs in sub-Saharan Africa and south Asia, and supplementary feeding is often offered in conjunction with ART. Evidence for the effectiveness of such supplementary feeding is scant. A randomised, investigator-blinded, controlled clinical trial of two types of supplementary food, corn/soy blended flour and a ready-to-use peanut butter-based lipid paste, in wasted adults in Blantyre, Malawi is described and the results summarised. A historical control group who did not receive supplementary food is described as well. Provision of about half of the daily energy requirement as a supplementary food for 14 weeks resulted in more rapid restoration of a normal BMI; and the energy-dense, ready-to-use paste was associated with more rapid weight gain than the blended flour. Survival was similar among the 3 groups. The strong association between lower BMI and survival indirectly suggests that there may well be clinical benefit from supplementary feeding in this population. No differences were seen in ART adherence or quality of life with more rapid restoration of BMI. Further research is urgently needed concerning the widespread practice of supplementary feeding in HIV/AIDS care to most effectively utilize this intervention.

PubMed: 21614881

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Mark Manary

<affiliation><nlm:affiliation>Department of Public Health, College of Medicine, University of Malawi.</nlm:affiliation>
<wicri:noCountry code="subField">University of Malawi</wicri:noCountry>
</affiliation>

Le document en format XML

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<term>CD4 Lymphocyte Count</term>
<term>Female</term>
<term>HIV Infections (complications)</term>
<term>HIV Infections (drug therapy)</term>
<term>HIV Wasting Syndrome (diet therapy)</term>
<term>HIV Wasting Syndrome (economics)</term>
<term>Humans</term>
<term>Malawi</term>
<term>Male</term>
<term>Quality of Life</term>
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<term>Antirétroviraux (usage thérapeutique)</term>
<term>Arachis</term>
<term>Charge virale</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
<term>Infections à VIH ()</term>
<term>Infections à VIH (traitement médicamenteux)</term>
<term>Malawi</term>
<term>Mâle</term>
<term>Numération des lymphocytes CD4</term>
<term>Prise de poids</term>
<term>Produits alimentaires à base de soja</term>
<term>Qualité de vie</term>
<term>Résultat thérapeutique</term>
<term>Syndrome cachectique  lié au VIH (diétothérapie)</term>
<term>Syndrome cachectique  lié au VIH (économie)</term>
<term>Zea mays</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Retroviral Agents</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Malawi</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term>
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<keywords scheme="MESH" qualifier="diet therapy" xml:lang="en"><term>HIV Wasting Syndrome</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term>
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<keywords scheme="MESH" qualifier="economics" xml:lang="en"><term>HIV Wasting Syndrome</term>
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<term>Arachis</term>
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<term>CD4 Lymphocyte Count</term>
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<term>Humans</term>
<term>Male</term>
<term>Quality of Life</term>
<term>Soy Foods</term>
<term>Treatment Outcome</term>
<term>Viral Load</term>
<term>Weight Gain</term>
<term>Zea mays</term>
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<term>Arachis</term>
<term>Charge virale</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de masse corporelle</term>
<term>Infections à VIH</term>
<term>Malawi</term>
<term>Mâle</term>
<term>Numération des lymphocytes CD4</term>
<term>Prise de poids</term>
<term>Produits alimentaires à base de soja</term>
<term>Qualité de vie</term>
<term>Résultat thérapeutique</term>
<term>Zea mays</term>
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<front><div type="abstract" xml:lang="en">Wasting and food insecurity are commonly seen in patients receiving antiretroviral treatment (ART) programs in sub-Saharan Africa and south Asia, and supplementary feeding is often offered in conjunction with ART. Evidence for the effectiveness of such supplementary feeding is scant. A randomised, investigator-blinded, controlled clinical trial of two types of supplementary food, corn/soy blended flour and a ready-to-use peanut butter-based lipid paste, in wasted adults in Blantyre, Malawi is described and the results summarised. A historical control group who did not receive supplementary food is described as well. Provision of about half of the daily energy requirement as a supplementary food for 14 weeks resulted in more rapid restoration of a normal BMI; and the energy-dense, ready-to-use paste was associated with more rapid weight gain than the blended flour. Survival was similar among the 3 groups. The strong association between lower BMI and survival indirectly suggests that there may well be clinical benefit from supplementary feeding in this population. No differences were seen in ART adherence or quality of life with more rapid restoration of BMI. Further research is urgently needed concerning the widespread practice of supplementary feeding in HIV/AIDS care to most effectively utilize this intervention.</div>
</front>
</TEI>
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Supplementary feeding in the care of the wasted HIV infected patient.

Supplementary feeding in the care of the wasted HIV infected patient.

Source :

Descripteurs français

English descriptors

Abstract

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Curation

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