SidaSubSaharaV1, Istex, Corpus, bibRecord, 003650

Low birthweight in infants born to African HIV-infected women: relationship with maternal body weight during pregnancy

Identifieur interne : 003650 ( Istex/Corpus ); précédent : 003649; suivant : 003651

Low birthweight in infants born to African HIV-infected women: relationship with maternal body weight during pregnancy

Auteurs : K. Castetbon ; J. Ladner ; V. Leroy ; M. Chauliac ; E. Karita ; A. De Clercq ; P. Van De Perre ; F. Dabis ; F. Pregnancy ; Hiv Study Group Ege

Source :

Journal of Tropical Pediatrics [ 0142-6338 ] ; 1999-06.

RBID : ISTEX:A59B1819DBA823289198105F1E7F36C72A852C01

English descriptors

Abstract

The effect of maternal HIV infection on birthweight was estimated. In the prenatal clinic of the Centre Hospitalier de Kigali, HIV screening was proposed to women with a gestational age (GA) of less than 28 weeks. HIV-infected (HIV+) and uninfected (HIF-) women were recruited, when they consented. At inclusion, socioeconomic, obstetrical data, and body weight were collected a clinical examination was performed, and tests for sexually transmitted diseases (STDs) and malaria were performed. Two prenatal visits were made, at 28-32 and 32-36 weeks, with clinical data and weight measurement. At delivery, birthweight, body length, and head circumference of the infant were documented. At inclusion and at the second follow-up visit, HIV+ women (N = 177) weighted less than HIV- women (N = 194) (p = 0.004). Mean birthweight in infants born to HIV+ women was 2947 g (SD = 429) and 3104 g (SD = 461) in infants born to HIV- women (p = 0.001). Frequencies of low birthweight (LBW, weight <2500 g), prematurity (GA <27 weeks, according to Finnström score at birth), and intrauterine growth retardation (defined by LBW and GA ≥37 weeks) were higher in infants born to HIV+ women than to HIV- women (p = 0.009, 0.01, and 0.053, respectively). In multivariate logistic regression, the association between maternal HIV infection and LBW disappeared (p = 0.61), while low GA (p = 0.01) and low last prenatal weight (p = 0.01) were independant risk factors of LBW. LBW in infants born to HIV+ women could be partly attributable to impaired maternal weight. These results underline the need for nutritional surveillance and dietary counselling, hoping to improve the prognosis of pregnancy in HIV+ women, regardless of other therapeutic interventions.

Url:

https://api.istex.fr/document/A59B1819DBA823289198105F1E7F36C72A852C01/fulltext/pdf

DOI: 10.1093/tropej/45.3.152

Links to Exploration step

ISTEX:A59B1819DBA823289198105F1E7F36C72A852C01

Le document en format XML

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<front><div type="abstract" xml:lang="en">The effect of maternal HIV infection on birthweight was estimated. In the prenatal clinic of the Centre Hospitalier de Kigali, HIV screening was proposed to women with a gestational age (GA) of less than 28 weeks. HIV-infected (HIV+) and uninfected (HIF-) women were recruited, when they consented. At inclusion, socioeconomic, obstetrical data, and body weight were collected a clinical examination was performed, and tests for sexually transmitted diseases (STDs) and malaria were performed. Two prenatal visits were made, at 28-32 and 32-36 weeks, with clinical data and weight measurement. At delivery, birthweight, body length, and head circumference of the infant were documented. At inclusion and at the second follow-up visit, HIV+ women (N = 177) weighted less than HIV- women (N = 194) (p = 0.004). Mean birthweight in infants born to HIV+ women was 2947 g (SD = 429) and 3104 g (SD = 461) in infants born to HIV- women (p = 0.001). Frequencies of low birthweight (LBW, weight <2500 g), prematurity (GA <27 weeks, according to Finnström score at birth), and intrauterine growth retardation (defined by LBW and GA ≥37 weeks) were higher in infants born to HIV+ women than to HIV- women (p = 0.009, 0.01, and 0.053, respectively). In multivariate logistic regression, the association between maternal HIV infection and LBW disappeared (p = 0.61), while low GA (p = 0.01) and low last prenatal weight (p = 0.01) were independant risk factors of LBW. LBW in infants born to HIV+ women could be partly attributable to impaired maternal weight. These results underline the need for nutritional surveillance and dietary counselling, hoping to improve the prognosis of pregnancy in HIV+ women, regardless of other therapeutic interventions.</div>
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      <p>The effect of maternal HIV infection on birthweight was estimated. In the prenatal clinic of the Centre Hospitalier de Kigali, HIV screening was proposed to women with a gestational age (GA) of less than 28 weeks. HIV-infected (HIV+) and uninfected (HIF-) women were recruited, when they consented. At inclusion, socioeconomic, obstetrical data, and body weight were collected a clinical examination was performed, and tests for sexually transmitted diseases (STDs) and malaria were performed. Two prenatal visits were made, at 28-32 and 32-36 weeks, with clinical data and weight measurement. At delivery, birthweight, body length, and head circumference of the infant were documented. At inclusion and at the second follow-up visit, HIV+ women (N = 177) weighted less than HIV- women (N = 194) (p = 0.004). Mean birthweight in infants born to HIV+ women was 2947 g (SD = 429) and 3104 g (SD = 461) in infants born to HIV- women (p = 0.001). Frequencies of low birthweight (LBW, weight <2500 g), prematurity (GA <27 weeks, according to Finnström score at birth), and intrauterine growth retardation (defined by LBW and GA ≥37 weeks) were higher in infants born to HIV+ women than to HIV- women (p = 0.009, 0.01, and 0.053, respectively). In multivariate logistic regression, the association between maternal HIV infection and LBW disappeared (p = 0.61), while low GA (p = 0.01) and low last prenatal weight (p = 0.01) were independant risk factors of LBW. LBW in infants born to HIV+ women could be partly attributable to impaired maternal weight. These results underline the need for nutritional surveillance and dietary counselling, hoping to improve the prognosis of pregnancy in HIV+ women, regardless of other therapeutic interventions.</p>

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	Le SIDA en Afrique subsaharienne (serveur d'exploration)
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Le SIDA en Afrique subsaharienne (serveur d'exploration)

Low birthweight in infants born to African HIV-infected women: relationship with maternal body weight during pregnancy

Low birthweight in infants born to African HIV-infected women: relationship with maternal body weight during pregnancy

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