Impact of HIV infection on tuberculosis
Identifieur interne : 001399 ( Istex/Corpus ); précédent : 001398; suivant : 001400Impact of HIV infection on tuberculosis
Auteurs : Alimuddin Zumla ; Patrick Malon ; Jane Henderson ; John M. GrangeSource :
- Postgraduate Medical Journal [ 0032-5473 ] ; 2000-05-01.
English descriptors
- KwdEn :
- Active tuberculosis, African patients, Aids patients, Antiretroviral drugs, Antituberculosis, Antituberculosis agents, Antituberculosis chemotherapy, Antituberculosis regimen, Antituberculosis treatment, Asymmetrical lymphadenopathy, Attenuated vaccine, Atypical presentations, Bacillus, Bovis, Cattle tuberculosis, Cavity formation, Cell counts, Chest radiography, Clin radiol, Clinical features, Clinical manifestations, Clinical specimens, Death world, Diagnostic diyculties, Disease control, Drug interactions, Drug resistance, East asia, Environmental mycobacteria, Evect, Evects, Global burden, Global perspective, Grange, High incidence, High proportion, High risk, Human tuberculosis, Human virus, Human virus infection, Hypersensitivity reactions, Immune, Important cause, Incidence, Infection, Inhibitor, International journal, International union, Isoniazid, Lesion, Lung disease, Lymphocyte count, Lymphocyte counts, Major problem, Malon, Maternal death, Mature epithelioid cells, Mmwr morb, Molecular methods, Month course, Multiple choice questions, Mycobacteria, Mycobacterium, Mycobacterium bovis, Mycobacterium tuberculosis, Negative patients, Organisation, Other drugs, Overt tuberculosis, Placebo group, Positive children, Positive cultures, Positive patients, Positive persons, Protease inhibitors, Pulmonary tuberculosis, Radiological, Radiological appearance, Radiological features, Randomised trial, Recent infection, Regimen, Relapse rate, Respir crit care, Rifampicin, Rifampicin resistance, Rpob gene, Serious problems, Serological tests, Seronegative patients, Seropositive patients, Seroprevalence rate, Side evects, Slim disease, Source case, Source cases, Sputum, Sputum specimens, System involvement, Thiacetazone, Transcriptase inhibitors, Tuber lung, Tubercle, Tubercle bacilli, Tubercle bacillus, Tuberculin skin tests, Tuberculosis, Tuberculosis patients, Uninfected patients, Vaccination, Weight loss, World health organisation, York city, Zambia, Zambian children, Zumla.
- Teeft :
- Active tuberculosis, African patients, Aids patients, Antiretroviral drugs, Antituberculosis, Antituberculosis agents, Antituberculosis chemotherapy, Antituberculosis regimen, Antituberculosis treatment, Asymmetrical lymphadenopathy, Attenuated vaccine, Atypical presentations, Bacillus, Bovis, Cattle tuberculosis, Cavity formation, Cell counts, Chest radiography, Clin radiol, Clinical features, Clinical manifestations, Clinical specimens, Death world, Diagnostic diyculties, Disease control, Drug interactions, Drug resistance, East asia, Environmental mycobacteria, Evect, Evects, Global burden, Global perspective, Grange, High incidence, High proportion, High risk, Human tuberculosis, Human virus, Human virus infection, Hypersensitivity reactions, Immune, Important cause, Incidence, Infection, Inhibitor, International journal, International union, Isoniazid, Lesion, Lung disease, Lymphocyte count, Lymphocyte counts, Major problem, Malon, Maternal death, Mature epithelioid cells, Mmwr morb, Molecular methods, Month course, Multiple choice questions, Mycobacteria, Mycobacterium, Mycobacterium bovis, Mycobacterium tuberculosis, Negative patients, Organisation, Other drugs, Overt tuberculosis, Placebo group, Positive children, Positive cultures, Positive patients, Positive persons, Protease inhibitors, Pulmonary tuberculosis, Radiological, Radiological appearance, Radiological features, Randomised trial, Recent infection, Regimen, Relapse rate, Respir crit care, Rifampicin, Rifampicin resistance, Rpob gene, Serious problems, Serological tests, Seronegative patients, Seropositive patients, Seroprevalence rate, Side evects, Slim disease, Source case, Source cases, Sputum, Sputum specimens, System involvement, Thiacetazone, Transcriptase inhibitors, Tuber lung, Tubercle, Tubercle bacilli, Tubercle bacillus, Tuberculin skin tests, Tuberculosis, Tuberculosis patients, Uninfected patients, Vaccination, Weight loss, World health organisation, York city, Zambia, Zambian children, Zumla.
Abstract
Tuberculosis is increasing in prevalence in many countries and is now the leading infectious cause of death world wide, being responsible for three million deaths annually. Infection with HIV, likewise increasing in prevalence, has emerged as the most important predisposing factor for developing overt tuberculosis in people co-infected with Mycobacterium tuberculosis. Owing to the widespread geographical overlap of these two infections, it is estimated that in 1999, HIV related tuberculosis will reach one million cases and will cause 30% of the expected 2.5 million AIDS related deaths. Tuberculosis in HIV infected individuals may have unusual clinical features and can cause diagnostic difficulties. Despite the effectiveness of modern short course treatment, the mortality of HIV related tuberculosis during and after treatment remains high, and this may be due to other HIV related infections. The “cursed duet” of infection with both HIV andM tuberculosis is generating a threat to human health of unparalleled proportions which, if not taken seriously by health workers and decision makers, could become totally unmanageable.
Url:
DOI: 10.1136/pmj.76.895.259
Links to Exploration step
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<front><div type="abstract" xml:lang="en">Tuberculosis is increasing in prevalence in many countries and is now the leading infectious cause of death world wide, being responsible for three million deaths annually. Infection with HIV, likewise increasing in prevalence, has emerged as the most important predisposing factor for developing overt tuberculosis in people co-infected with Mycobacterium tuberculosis. Owing to the widespread geographical overlap of these two infections, it is estimated that in 1999, HIV related tuberculosis will reach one million cases and will cause 30% of the expected 2.5 million AIDS related deaths. Tuberculosis in HIV infected individuals may have unusual clinical features and can cause diagnostic difficulties. Despite the effectiveness of modern short course treatment, the mortality of HIV related tuberculosis during and after treatment remains high, and this may be due to other HIV related infections. The “cursed duet” of infection with both HIV andM tuberculosis is generating a threat to human health of unparalleled proportions which, if not taken seriously by health workers and decision makers, could become totally unmanageable.</div>
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<abstract>Tuberculosis is increasing in prevalence in many countries and is now the leading infectious cause of death world wide, being responsible for three million deaths annually. Infection with HIV, likewise increasing in prevalence, has emerged as the most important predisposing factor for developing overt tuberculosis in people co-infected with Mycobacterium tuberculosis. Owing to the widespread geographical overlap of these two infections, it is estimated that in 1999, HIV related tuberculosis will reach one million cases and will cause 30% of the expected 2.5 million AIDS related deaths. Tuberculosis in HIV infected individuals may have unusual clinical features and can cause diagnostic difficulties. Despite the effectiveness of modern short course treatment, the mortality of HIV related tuberculosis during and after treatment remains high, and this may be due to other HIV related infections. The “cursed duet” of infection with both HIV andM tuberculosis is generating a threat to human health of unparalleled proportions which, if not taken seriously by health workers and decision makers, could become totally unmanageable.</abstract>
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