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Impact of HIV infection on tuberculosis

Identifieur interne : 001399 ( Istex/Corpus ); précédent : 001398; suivant : 001400

Impact of HIV infection on tuberculosis

Auteurs : Alimuddin Zumla ; Patrick Malon ; Jane Henderson ; John M. Grange

Source :

RBID : ISTEX:3DD18688F96FB3E5DA5C0E7706C1C3F6C9253545

English descriptors

Abstract

Tuberculosis is increasing in prevalence in many countries and is now the leading infectious cause of death world wide, being responsible for three million deaths annually. Infection with HIV, likewise increasing in prevalence, has emerged as the most important predisposing factor for developing overt tuberculosis in people co-infected with Mycobacterium tuberculosis. Owing to the widespread geographical overlap of these two infections, it is estimated that in 1999, HIV related tuberculosis will reach one million cases and will cause 30% of the expected 2.5 million AIDS related deaths. Tuberculosis in HIV infected individuals may have unusual clinical features and can cause diagnostic difficulties. Despite the effectiveness of modern short course treatment, the mortality of HIV related tuberculosis during and after treatment remains high, and this may be due to other HIV related infections. The “cursed duet” of infection with both HIV andM tuberculosis is generating a threat to human health of unparalleled proportions which, if not taken seriously by health workers and decision makers, could become totally unmanageable.

Url:
DOI: 10.1136/pmj.76.895.259

Links to Exploration step

ISTEX:3DD18688F96FB3E5DA5C0E7706C1C3F6C9253545

Le document en format XML

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