Protective effect of Dunaliella sp., lipid extract rich in polyunsaturated fatty acids, on hepatic and renal toxicity induced by nickel in rats.
Identifieur interne : 000027 ( PubMed/Corpus ); précédent : 000026; suivant : 000028Protective effect of Dunaliella sp., lipid extract rich in polyunsaturated fatty acids, on hepatic and renal toxicity induced by nickel in rats.
Auteurs : Ines Dahmen-Ben Moussa ; Khaled Bellassoued ; Khaled Athmouni ; Manel Naifar ; Haifa Chtourou ; Habib Ayadi ; Fatma Makni-Ayadi ; Sami Sayadi ; Abdelfatteh El Feki ; Abdelhafidh DhouibSource :
- Toxicology mechanisms and methods [ 1537-6524 ] ; 2016.
English descriptors
- KwdEn :
- Animals, Antioxidants (isolation & purification), Antioxidants (pharmacology), Biphenyl Compounds (chemistry), Body Weight (drug effects), Chlorophyta (chemistry), Fatty Acids, Unsaturated (pharmacology), Female, Kidney (drug effects), Kidney (enzymology), Kidney (pathology), Kidney Function Tests, Liver (drug effects), Liver (enzymology), Liver (pathology), Liver Function Tests, Nickel (toxicity), Organ Size (drug effects), Oxidative Stress (drug effects), Picrates (chemistry), Plant Extracts (isolation & purification), Plant Extracts (pharmacology), Rats, Wistar.
- MESH :
- chemical , chemistry : Biphenyl Compounds, Picrates.
- chemical , isolation & purification : Antioxidants, Plant Extracts.
- chemical , pharmacology : Antioxidants, Fatty Acids, Unsaturated, Plant Extracts.
- chemistry : Chlorophyta.
- drug effects : Body Weight, Kidney, Liver, Organ Size, Oxidative Stress.
- enzymology : Kidney, Liver.
- pathology : Kidney, Liver.
- chemical , toxicity : Nickel.
- Animals, Female, Kidney Function Tests, Liver Function Tests, Rats, Wistar.
Abstract
The present study was undertaken to investigate the protective effect of lipid extract of Dunaliella sp. (LE) rich in polyunsaturated fatty acids (PUFA), against oxidative stress induced by nickel in experimental rats.
DOI: 10.3109/15376516.2016.1158340
PubMed: 27001662
Links to Exploration step
pubmed:27001662Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Protective effect of Dunaliella sp., lipid extract rich in polyunsaturated fatty acids, on hepatic and renal toxicity induced by nickel in rats.</title><author><name sortKey="Dahmen Ben Moussa, Ines" sort="Dahmen Ben Moussa, Ines" uniqKey="Dahmen Ben Moussa I" first="Ines" last="Dahmen-Ben Moussa">Ines Dahmen-Ben Moussa</name><affiliation><nlm:affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Bellassoued, Khaled" sort="Bellassoued, Khaled" uniqKey="Bellassoued K" first="Khaled" last="Bellassoued">Khaled Bellassoued</name><affiliation><nlm:affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Athmouni, Khaled" sort="Athmouni, Khaled" uniqKey="Athmouni K" first="Khaled" last="Athmouni">Khaled Athmouni</name><affiliation><nlm:affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Naifar, Manel" sort="Naifar, Manel" uniqKey="Naifar M" first="Manel" last="Naifar">Manel Naifar</name><affiliation><nlm:affiliation>d Laboratory of Biochemistry , CHU Habib-Bourguiba , Sfax , Tunisia.</nlm:affiliation></affiliation></author><author><name sortKey="Chtourou, Haifa" sort="Chtourou, Haifa" uniqKey="Chtourou H" first="Haifa" last="Chtourou">Haifa Chtourou</name><affiliation><nlm:affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Ayadi, Habib" sort="Ayadi, Habib" uniqKey="Ayadi H" first="Habib" last="Ayadi">Habib Ayadi</name><affiliation><nlm:affiliation>c Department of life Sciences, Aquatic Ecosystem Biodiversity Research Unit, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia , and.</nlm:affiliation></affiliation></author><author><name sortKey="Makni Ayadi, Fatma" sort="Makni Ayadi, Fatma" uniqKey="Makni Ayadi F" first="Fatma" last="Makni-Ayadi">Fatma Makni-Ayadi</name><affiliation><nlm:affiliation>d Laboratory of Biochemistry , CHU Habib-Bourguiba , Sfax , Tunisia.</nlm:affiliation></affiliation></author><author><name sortKey="Sayadi, Sami" sort="Sayadi, Sami" uniqKey="Sayadi S" first="Sami" last="Sayadi">Sami Sayadi</name><affiliation><nlm:affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="El Feki, Abdelfatteh" sort="El Feki, Abdelfatteh" uniqKey="El Feki A" first="Abdelfatteh" last="El Feki">Abdelfatteh El Feki</name><affiliation><nlm:affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Dhouib, Abdelhafidh" sort="Dhouib, Abdelhafidh" uniqKey="Dhouib A" first="Abdelhafidh" last="Dhouib">Abdelhafidh Dhouib</name><affiliation><nlm:affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27001662</idno><idno type="pmid">27001662</idno><idno type="doi">10.3109/15376516.2016.1158340</idno><idno type="wicri:Area/PubMed/Corpus">000027</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000027</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Protective effect of Dunaliella sp., lipid extract rich in polyunsaturated fatty acids, on hepatic and renal toxicity induced by nickel in rats.</title><author><name sortKey="Dahmen Ben Moussa, Ines" sort="Dahmen Ben Moussa, Ines" uniqKey="Dahmen Ben Moussa I" first="Ines" last="Dahmen-Ben Moussa">Ines Dahmen-Ben Moussa</name><affiliation><nlm:affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Bellassoued, Khaled" sort="Bellassoued, Khaled" uniqKey="Bellassoued K" first="Khaled" last="Bellassoued">Khaled Bellassoued</name><affiliation><nlm:affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Athmouni, Khaled" sort="Athmouni, Khaled" uniqKey="Athmouni K" first="Khaled" last="Athmouni">Khaled Athmouni</name><affiliation><nlm:affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Naifar, Manel" sort="Naifar, Manel" uniqKey="Naifar M" first="Manel" last="Naifar">Manel Naifar</name><affiliation><nlm:affiliation>d Laboratory of Biochemistry , CHU Habib-Bourguiba , Sfax , Tunisia.</nlm:affiliation></affiliation></author><author><name sortKey="Chtourou, Haifa" sort="Chtourou, Haifa" uniqKey="Chtourou H" first="Haifa" last="Chtourou">Haifa Chtourou</name><affiliation><nlm:affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Ayadi, Habib" sort="Ayadi, Habib" uniqKey="Ayadi H" first="Habib" last="Ayadi">Habib Ayadi</name><affiliation><nlm:affiliation>c Department of life Sciences, Aquatic Ecosystem Biodiversity Research Unit, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia , and.</nlm:affiliation></affiliation></author><author><name sortKey="Makni Ayadi, Fatma" sort="Makni Ayadi, Fatma" uniqKey="Makni Ayadi F" first="Fatma" last="Makni-Ayadi">Fatma Makni-Ayadi</name><affiliation><nlm:affiliation>d Laboratory of Biochemistry , CHU Habib-Bourguiba , Sfax , Tunisia.</nlm:affiliation></affiliation></author><author><name sortKey="Sayadi, Sami" sort="Sayadi, Sami" uniqKey="Sayadi S" first="Sami" last="Sayadi">Sami Sayadi</name><affiliation><nlm:affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="El Feki, Abdelfatteh" sort="El Feki, Abdelfatteh" uniqKey="El Feki A" first="Abdelfatteh" last="El Feki">Abdelfatteh El Feki</name><affiliation><nlm:affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</nlm:affiliation></affiliation></author><author><name sortKey="Dhouib, Abdelhafidh" sort="Dhouib, Abdelhafidh" uniqKey="Dhouib A" first="Abdelhafidh" last="Dhouib">Abdelhafidh Dhouib</name><affiliation><nlm:affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</nlm:affiliation></affiliation></author></analytic><series><title level="j">Toxicology mechanisms and methods</title><idno type="eISSN">1537-6524</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antioxidants (isolation & purification)</term><term>Antioxidants (pharmacology)</term><term>Biphenyl Compounds (chemistry)</term><term>Body Weight (drug effects)</term><term>Chlorophyta (chemistry)</term><term>Fatty Acids, Unsaturated (pharmacology)</term><term>Female</term><term>Kidney (drug effects)</term><term>Kidney (enzymology)</term><term>Kidney (pathology)</term><term>Kidney Function Tests</term><term>Liver (drug effects)</term><term>Liver (enzymology)</term><term>Liver (pathology)</term><term>Liver Function Tests</term><term>Nickel (toxicity)</term><term>Organ Size (drug effects)</term><term>Oxidative Stress (drug effects)</term><term>Picrates (chemistry)</term><term>Plant Extracts (isolation & purification)</term><term>Plant Extracts (pharmacology)</term><term>Rats, Wistar</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Biphenyl Compounds</term><term>Picrates</term></keywords><keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>Antioxidants</term><term>Plant Extracts</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antioxidants</term><term>Fatty Acids, Unsaturated</term><term>Plant Extracts</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Chlorophyta</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Body Weight</term><term>Kidney</term><term>Liver</term><term>Organ Size</term><term>Oxidative Stress</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Kidney</term><term>Liver</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Kidney</term><term>Liver</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Nickel</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Female</term><term>Kidney Function Tests</term><term>Liver Function Tests</term><term>Rats, Wistar</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The present study was undertaken to investigate the protective effect of lipid extract of Dunaliella sp. (LE) rich in polyunsaturated fatty acids (PUFA), against oxidative stress induced by nickel in experimental rats.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27001662</PMID><DateCreated><Year>2016</Year><Month>04</Month><Day>07</Day></DateCreated><DateCompleted><Year>2016</Year><Month>12</Month><Day>23</Day></DateCompleted><DateRevised><Year>2016</Year><Month>12</Month><Day>30</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1537-6524</ISSN><JournalIssue CitedMedium="Internet"><Volume>26</Volume><Issue>3</Issue><PubDate><Year>2016</Year></PubDate></JournalIssue><Title>Toxicology mechanisms and methods</Title><ISOAbbreviation>Toxicol. Mech. Methods</ISOAbbreviation></Journal><ArticleTitle>Protective effect of Dunaliella sp., lipid extract rich in polyunsaturated fatty acids, on hepatic and renal toxicity induced by nickel in rats.</ArticleTitle><Pagination><MedlinePgn>221-30</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3109/15376516.2016.1158340</ELocationID><Abstract><AbstractText Label="AIMS" NlmCategory="OBJECTIVE">The present study was undertaken to investigate the protective effect of lipid extract of Dunaliella sp. (LE) rich in polyunsaturated fatty acids (PUFA), against oxidative stress induced by nickel in experimental rats.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Our investigation evaluated the antioxidant activity of LE using both DPPH and NBT assays. Twenty female albino Wistar rats, randomly allocated into four experimental groups, namely (C): control, (Nit): nickel-treated rats with 5 mg/kg/d of NiCl2 during 30 days, (LEa): lipid extract-administered rats with 5 mg/kg BW/d during 30 days and (Nit + LEa): rats treated with Ni and LE-administered during 30 days.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The in vitro antioxidant activity demonstrated that LE presents an important antioxidant potential. In vivo, the (Nit + LEa) cotreatment decreased the level of malondialdehyde and restored the antioxidant enzyme activities (superoxide dismutase, catalase and glutathione peroxidase) in livers and kidneys in comparison with those treated with Ni only. LE administration to rats treated with Ni also ameliorated biochemical and histological parameters as compared to only Ni-treated group. LE of Dunaliella sp., rich in polyunsaturated fatty acids showed a significant hepato- and reno-protective effect against metal-induced toxicity.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">LE of Dunaliella sp., rich in PUFA has been proven to be effective in protection against Ni-induced toxicity.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dahmen-Ben Moussa</LastName><ForeName>Ines</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bellassoued</LastName><ForeName>Khaled</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Athmouni</LastName><ForeName>Khaled</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>c Department of life Sciences, Aquatic Ecosystem Biodiversity Research Unit, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia , and.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Naifar</LastName><ForeName>Manel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>d Laboratory of Biochemistry , CHU Habib-Bourguiba , Sfax , Tunisia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chtourou</LastName><ForeName>Haifa</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ayadi</LastName><ForeName>Habib</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>c Department of life Sciences, Aquatic Ecosystem Biodiversity Research Unit, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia , and.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Makni-Ayadi</LastName><ForeName>Fatma</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>d Laboratory of Biochemistry , CHU Habib-Bourguiba , Sfax , Tunisia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sayadi</LastName><ForeName>Sami</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>El Feki</LastName><ForeName>Abdelfatteh</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>b Department of life Sciences, Laboratory of Animal Ecophysiology, Faculty of Sciences of Sfax , University of Sfax , Sfax , Tunisia .</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dhouib</LastName><ForeName>Abdelhafidh</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>a Laboratory of Environmental Bioprocesses , Centre of Biotechnology of Sfax, University of Sfax , Sfax Tunisia .</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>03</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Toxicol Mech Methods</MedlineTA><NlmUniqueID>101134521</NlmUniqueID><ISSNLinking>1537-6516</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000975">Antioxidants</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001713">Biphenyl Compounds</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005231">Fatty Acids, Unsaturated</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010851">Picrates</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010936">Plant Extracts</NameOfSubstance></Chemical><Chemical><RegistryNumber>7OV03QG267</RegistryNumber><NameOfSubstance UI="D009532">Nickel</NameOfSubstance></Chemical><Chemical><RegistryNumber>DFD3H4VGDH</RegistryNumber><NameOfSubstance UI="C004931">1,1-diphenyl-2-picrylhydrazyl</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000975" MajorTopicYN="N">Antioxidants</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001713" MajorTopicYN="N">Biphenyl Compounds</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001835" MajorTopicYN="N">Body Weight</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000460" MajorTopicYN="N">Chlorophyta</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005231" MajorTopicYN="N">Fatty Acids, Unsaturated</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007668" MajorTopicYN="N">Kidney</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName><QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007677" MajorTopicYN="N">Kidney Function Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008099" MajorTopicYN="N">Liver</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName><QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008111" MajorTopicYN="N">Liver Function Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009532" MajorTopicYN="N">Nickel</DescriptorName><QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009929" MajorTopicYN="N">Organ Size</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018384" MajorTopicYN="N">Oxidative Stress</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010851" MajorTopicYN="N">Picrates</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010936" MajorTopicYN="N">Plant Extracts</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017208" MajorTopicYN="N">Rats, Wistar</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Kidney</Keyword><Keyword MajorTopicYN="N">PUFA</Keyword><Keyword MajorTopicYN="N">liver</Keyword><Keyword MajorTopicYN="N">nickel</Keyword><Keyword MajorTopicYN="N">oxidative stress</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>3</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>3</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>12</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27001662</ArticleId><ArticleId IdType="doi">10.3109/15376516.2016.1158340</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/NickelMaghrebV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000027 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000027 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Terre
|area= NickelMaghrebV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:27001662
|texte= Protective effect of Dunaliella sp., lipid extract rich in polyunsaturated fatty acids, on hepatic and renal toxicity induced by nickel in rats.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:27001662" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a NickelMaghrebV1
| This area was generated with Dilib version V0.6.27. |  |