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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The value of plants used in traditional medicine for drug discovery.</title><author><name sortKey="Fabricant, D S" sort="Fabricant, D S" uniqKey="Fabricant D" first="D S" last="Fabricant">D S Fabricant</name></author><author><name sortKey="Farnsworth, N R" sort="Farnsworth, N R" uniqKey="Farnsworth N" first="N R" last="Farnsworth">N R Farnsworth</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">11250806</idno><idno type="pmc">1240543</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240543</idno><idno type="RBID">PMC:1240543</idno><date when="2001">2001</date><idno type="wicri:Area/Pmc/Corpus">000117</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000117</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The value of plants used in traditional medicine for drug discovery.</title><author><name sortKey="Fabricant, D S" sort="Fabricant, D S" uniqKey="Fabricant D" first="D S" last="Fabricant">D S Fabricant</name></author><author><name sortKey="Farnsworth, N R" sort="Farnsworth, N R" uniqKey="Farnsworth N" first="N R" last="Farnsworth">N R Farnsworth</name></author></analytic><series><title level="j">Environmental Health Perspectives</title><idno type="ISSN">0091-6765</idno><imprint><date when="2001">2001</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In this review we describe and discuss several approaches to selecting higher plants as candidates for drug development with the greatest possibility of success. We emphasize the role of information derived from various systems of traditional medicine (ethnomedicine) and its utility for drug discovery purposes. We have identified 122 compounds of defined structure, obtained from only 94 species of plants, that are used globally as drugs and demonstrate that 80% of these have had an ethnomedical use identical or related to the current use of the active elements of the plant. We identify and discuss advantages and disadvantages of using plants as starting points for drug development, specifically those used in traditional medicine.</p></div></front></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Environ Health Perspect</journal-id><journal-title>Environmental Health Perspectives</journal-title><issn pub-type="ppub">0091-6765</issn></journal-meta><article-meta><article-id pub-id-type="pmid">11250806</article-id><article-id pub-id-type="pmc">1240543</article-id><article-id pub-id-type="pii">sc271_5_1835</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>The value of plants used in traditional medicine for drug discovery.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Fabricant</surname><given-names>D S</given-names></name></contrib><contrib contrib-type="author"><name><surname>Farnsworth</surname><given-names>N R</given-names></name></contrib></contrib-group><aff>Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois-Chicago, Chicago, Illinois 60612, USA. dfabri1@uic.edu</aff><pub-date pub-type="ppub"><month>3</month><year>2001</year></pub-date><volume>109</volume><issue>Suppl 1</issue><fpage>69</fpage><lpage>75</lpage><abstract><p>In this review we describe and discuss several approaches to selecting higher plants as candidates for drug development with the greatest possibility of success. We emphasize the role of information derived from various systems of traditional medicine (ethnomedicine) and its utility for drug discovery purposes. We have identified 122 compounds of defined structure, obtained from only 94 species of plants, that are used globally as drugs and demonstrate that 80% of these have had an ethnomedical use identical or related to the current use of the active elements of the plant. We identify and discuss advantages and disadvantages of using plants as starting points for drug development, specifically those used in traditional medicine.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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