Human mitochondrial DNA sequence variation in the Moroccan population of the Souss area.
Identifieur interne : 000010 ( Ncbi/Merge ); précédent : 000009; suivant : 000011Human mitochondrial DNA sequence variation in the Moroccan population of the Souss area.
Auteurs : Z. Brakez [Maroc] ; E. Bosch ; H. Izaabel ; O. Akhayat ; D. Comas ; J. Bertranpetit ; F. CalafellSource :
- Annals of human biology [ 0301-4460 ]
Descripteurs français
- KwdFr :
- ADN mitochondrial (génétique), Afrique subsaharienne, Analyse de séquence d'ADN, Europe, Fréquence d'allèle (génétique), Groupes ethniques (), Groupes ethniques (génétique), Haplotypes, Humains, Linguistique (), Maroc, Pool des gènes, Régions déterminant la complémentarité (génétique), Séquence nucléotidique (génétique), Variation génétique (génétique), Émigration et immigration ().
- MESH :
- génétique : ADN mitochondrial, Fréquence d'allèle, Groupes ethniques, Régions déterminant la complémentarité, Séquence nucléotidique, Variation génétique.
- Afrique subsaharienne, Analyse de séquence d'ADN, Europe, Groupes ethniques, Haplotypes, Humains, Linguistique, Maroc, Pool des gènes, Émigration et immigration.
- Wicri :
- geographic : Maroc.
English descriptors
- KwdEn :
- Africa South of the Sahara, Base Sequence (genetics), Complementarity Determining Regions (genetics), DNA, Mitochondrial (genetics), Emigration and Immigration (statistics & numerical data), Ethnic Groups (genetics), Ethnic Groups (statistics & numerical data), Europe, Gene Frequency (genetics), Gene Pool, Genetic Variation (genetics), Haplotypes, Humans, Linguistics (statistics & numerical data), Morocco, Sequence Analysis, DNA.
- MESH :
- chemical , genetics : Complementarity Determining Regions, DNA, Mitochondrial.
- geographic : Africa South of the Sahara, Europe, Morocco.
- genetics : Base Sequence, Ethnic Groups, Gene Frequency, Genetic Variation.
- statistics & numerical data : Emigration and Immigration, Ethnic Groups, Linguistics.
- Gene Pool, Haplotypes, Humans, Sequence Analysis, DNA.
Abstract
Various populations have contributed to the present-day gene pool of Morocco, including the autochthonous Berber population, Phoenicians, Sephardic Jews, Bedouin Arabs and sub-Saharan Africans.
PubMed: 11393336
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- to stream PubMed, to step Corpus: 000027
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pubmed:11393336Le document en format XML
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<country xml:lang="fr">Maroc</country>
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<author><name sortKey="Akhayat, O" sort="Akhayat, O" uniqKey="Akhayat O" first="O" last="Akhayat">O. Akhayat</name>
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<author><name sortKey="Comas, D" sort="Comas, D" uniqKey="Comas D" first="D" last="Comas">D. Comas</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Africa South of the Sahara</term>
<term>Base Sequence (genetics)</term>
<term>Complementarity Determining Regions (genetics)</term>
<term>DNA, Mitochondrial (genetics)</term>
<term>Emigration and Immigration (statistics & numerical data)</term>
<term>Ethnic Groups (genetics)</term>
<term>Ethnic Groups (statistics & numerical data)</term>
<term>Europe</term>
<term>Gene Frequency (genetics)</term>
<term>Gene Pool</term>
<term>Genetic Variation (genetics)</term>
<term>Haplotypes</term>
<term>Humans</term>
<term>Linguistics (statistics & numerical data)</term>
<term>Morocco</term>
<term>Sequence Analysis, DNA</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>ADN mitochondrial (génétique)</term>
<term>Afrique subsaharienne</term>
<term>Analyse de séquence d'ADN</term>
<term>Europe</term>
<term>Fréquence d'allèle (génétique)</term>
<term>Groupes ethniques ()</term>
<term>Groupes ethniques (génétique)</term>
<term>Haplotypes</term>
<term>Humains</term>
<term>Linguistique ()</term>
<term>Maroc</term>
<term>Pool des gènes</term>
<term>Régions déterminant la complémentarité (génétique)</term>
<term>Séquence nucléotidique (génétique)</term>
<term>Variation génétique (génétique)</term>
<term>Émigration et immigration ()</term>
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<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Complementarity Determining Regions</term>
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<term>Genetic Variation</term>
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<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ADN mitochondrial</term>
<term>Fréquence d'allèle</term>
<term>Groupes ethniques</term>
<term>Régions déterminant la complémentarité</term>
<term>Séquence nucléotidique</term>
<term>Variation génétique</term>
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<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Emigration and Immigration</term>
<term>Ethnic Groups</term>
<term>Linguistics</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Gene Pool</term>
<term>Haplotypes</term>
<term>Humans</term>
<term>Sequence Analysis, DNA</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Afrique subsaharienne</term>
<term>Analyse de séquence d'ADN</term>
<term>Europe</term>
<term>Groupes ethniques</term>
<term>Haplotypes</term>
<term>Humains</term>
<term>Linguistique</term>
<term>Maroc</term>
<term>Pool des gènes</term>
<term>Émigration et immigration</term>
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<front><div type="abstract" xml:lang="en">Various populations have contributed to the present-day gene pool of Morocco, including the autochthonous Berber population, Phoenicians, Sephardic Jews, Bedouin Arabs and sub-Saharan Africans.</div>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">11393336</PMID>
<DateCreated><Year>2001</Year>
<Month>06</Month>
<Day>06</Day>
</DateCreated>
<DateCompleted><Year>2001</Year>
<Month>11</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised><Year>2008</Year>
<Month>11</Month>
<Day>21</Day>
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<Article PubModel="Print"><Journal><ISSN IssnType="Print">0301-4460</ISSN>
<JournalIssue CitedMedium="Print"><Volume>28</Volume>
<Issue>3</Issue>
<PubDate><MedlineDate>2001 May-Jun</MedlineDate>
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</JournalIssue>
<Title>Annals of human biology</Title>
<ISOAbbreviation>Ann. Hum. Biol.</ISOAbbreviation>
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<ArticleTitle>Human mitochondrial DNA sequence variation in the Moroccan population of the Souss area.</ArticleTitle>
<Pagination><MedlinePgn>295-307</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Various populations have contributed to the present-day gene pool of Morocco, including the autochthonous Berber population, Phoenicians, Sephardic Jews, Bedouin Arabs and sub-Saharan Africans.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The primary objective of the study was to complete a genetic description of the Berber-speaking population in the Souss region of southern Morocco, based on mitochondrial DNA (mtDNA) sequence analysis.</AbstractText>
<AbstractText Label="SUBJECTS AND METHODS" NlmCategory="METHODS">The first hypervariable segment of the mtDNA control region was sequenced in a sample of 50 individuals from the Souss Valley, and the results compared with the extensive body of data available on mtDNA sequence variation in Europe and sub-Saharan Africa.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Thirty-four different sequences were found: an estimated 68% of the sequences occurred throughout Europe, West Asia and North Africa, 26% originated in sub-Saharan Africa, and 6% belonged to the North African specific haplogroup U6. The Souss Valley mtDNA sequences indicated the presence of two populations which expanded at different times: the West Eurasian sequences in the Souss sample had a smaller average number of pairwise differences than pairs of sub-Saharan sequences.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Detailed knowledge of the possible geographic origin of each sequence facilitated an interpretation of both internal diversity parameters and between-population relationships. The sub-Saharan admixture in the Souss Valley matched the south-north cline of sub-Saharan influence in North Africa, also evident in the genetic distances of North African populations to Europeans and sub-Saharan Africans.</AbstractText>
</Abstract>
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<AffiliationInfo><Affiliation>Laboratoire de Biologic Cellulaire et Moléculaire, Faculté des Sciences, Université Ibnou-Zohr, Agadir, Morocco.</Affiliation>
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<Author ValidYN="Y"><LastName>Bosch</LastName>
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<Author ValidYN="Y"><LastName>Izaabel</LastName>
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<Author ValidYN="Y"><LastName>Akhayat</LastName>
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<Author ValidYN="Y"><LastName>Comas</LastName>
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<Author ValidYN="Y"><LastName>Bertranpetit</LastName>
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<MeshHeading><DescriptorName UI="D005060" MajorTopicYN="N" Type="Geographic">Europe</DescriptorName>
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<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
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<MeshHeading><DescriptorName UI="D006239" MajorTopicYN="N">Haplotypes</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<affiliations><list><country><li>Maroc</li>
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<name sortKey="Bertranpetit, J" sort="Bertranpetit, J" uniqKey="Bertranpetit J" first="J" last="Bertranpetit">J. Bertranpetit</name>
<name sortKey="Bosch, E" sort="Bosch, E" uniqKey="Bosch E" first="E" last="Bosch">E. Bosch</name>
<name sortKey="Calafell, F" sort="Calafell, F" uniqKey="Calafell F" first="F" last="Calafell">F. Calafell</name>
<name sortKey="Comas, D" sort="Comas, D" uniqKey="Comas D" first="D" last="Comas">D. Comas</name>
<name sortKey="Izaabel, H" sort="Izaabel, H" uniqKey="Izaabel H" first="H" last="Izaabel">H. Izaabel</name>
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<country name="Maroc"><noRegion><name sortKey="Brakez, Z" sort="Brakez, Z" uniqKey="Brakez Z" first="Z" last="Brakez">Z. Brakez</name>
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