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Human mitochondrial DNA sequence variation in the Moroccan population of the Souss area.

Identifieur interne : 000010 ( Ncbi/Merge ); précédent : 000009; suivant : 000011

Human mitochondrial DNA sequence variation in the Moroccan population of the Souss area.

Auteurs : Z. Brakez [Maroc] ; E. Bosch ; H. Izaabel ; O. Akhayat ; D. Comas ; J. Bertranpetit ; F. Calafell

Source :

RBID : pubmed:11393336

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English descriptors

Abstract

Various populations have contributed to the present-day gene pool of Morocco, including the autochthonous Berber population, Phoenicians, Sephardic Jews, Bedouin Arabs and sub-Saharan Africans.

PubMed: 11393336

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pubmed:11393336

Le document en format XML

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<nlm:affiliation>Laboratoire de Biologic Cellulaire et Moléculaire, Faculté des Sciences, Université Ibnou-Zohr, Agadir, Morocco.</nlm:affiliation>
<country xml:lang="fr">Maroc</country>
<wicri:regionArea>Laboratoire de Biologic Cellulaire et Moléculaire, Faculté des Sciences, Université Ibnou-Zohr, Agadir</wicri:regionArea>
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<name sortKey="Bosch, E" sort="Bosch, E" uniqKey="Bosch E" first="E" last="Bosch">E. Bosch</name>
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<name sortKey="Izaabel, H" sort="Izaabel, H" uniqKey="Izaabel H" first="H" last="Izaabel">H. Izaabel</name>
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<name sortKey="Akhayat, O" sort="Akhayat, O" uniqKey="Akhayat O" first="O" last="Akhayat">O. Akhayat</name>
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<name sortKey="Comas, D" sort="Comas, D" uniqKey="Comas D" first="D" last="Comas">D. Comas</name>
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<name sortKey="Bertranpetit, J" sort="Bertranpetit, J" uniqKey="Bertranpetit J" first="J" last="Bertranpetit">J. Bertranpetit</name>
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<name sortKey="Calafell, F" sort="Calafell, F" uniqKey="Calafell F" first="F" last="Calafell">F. Calafell</name>
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<name sortKey="Akhayat, O" sort="Akhayat, O" uniqKey="Akhayat O" first="O" last="Akhayat">O. Akhayat</name>
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<term>Africa South of the Sahara</term>
<term>Base Sequence (genetics)</term>
<term>Complementarity Determining Regions (genetics)</term>
<term>DNA, Mitochondrial (genetics)</term>
<term>Emigration and Immigration (statistics & numerical data)</term>
<term>Ethnic Groups (genetics)</term>
<term>Ethnic Groups (statistics & numerical data)</term>
<term>Europe</term>
<term>Gene Frequency (genetics)</term>
<term>Gene Pool</term>
<term>Genetic Variation (genetics)</term>
<term>Haplotypes</term>
<term>Humans</term>
<term>Linguistics (statistics & numerical data)</term>
<term>Morocco</term>
<term>Sequence Analysis, DNA</term>
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<term>ADN mitochondrial (génétique)</term>
<term>Afrique subsaharienne</term>
<term>Analyse de séquence d'ADN</term>
<term>Europe</term>
<term>Fréquence d'allèle (génétique)</term>
<term>Groupes ethniques ()</term>
<term>Groupes ethniques (génétique)</term>
<term>Haplotypes</term>
<term>Humains</term>
<term>Linguistique ()</term>
<term>Maroc</term>
<term>Pool des gènes</term>
<term>Régions déterminant la complémentarité (génétique)</term>
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<term>Variation génétique (génétique)</term>
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<term>Africa South of the Sahara</term>
<term>Europe</term>
<term>Morocco</term>
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<term>Base Sequence</term>
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<term>Gene Frequency</term>
<term>Genetic Variation</term>
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<term>ADN mitochondrial</term>
<term>Fréquence d'allèle</term>
<term>Groupes ethniques</term>
<term>Régions déterminant la complémentarité</term>
<term>Séquence nucléotidique</term>
<term>Variation génétique</term>
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<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en">
<term>Emigration and Immigration</term>
<term>Ethnic Groups</term>
<term>Linguistics</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Gene Pool</term>
<term>Haplotypes</term>
<term>Humans</term>
<term>Sequence Analysis, DNA</term>
</keywords>
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<term>Afrique subsaharienne</term>
<term>Analyse de séquence d'ADN</term>
<term>Europe</term>
<term>Groupes ethniques</term>
<term>Haplotypes</term>
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<front>
<div type="abstract" xml:lang="en">Various populations have contributed to the present-day gene pool of Morocco, including the autochthonous Berber population, Phoenicians, Sephardic Jews, Bedouin Arabs and sub-Saharan Africans.</div>
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<DateCreated>
<Year>2001</Year>
<Month>06</Month>
<Day>06</Day>
</DateCreated>
<DateCompleted>
<Year>2001</Year>
<Month>11</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised>
<Year>2008</Year>
<Month>11</Month>
<Day>21</Day>
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<ISSN IssnType="Print">0301-4460</ISSN>
<JournalIssue CitedMedium="Print">
<Volume>28</Volume>
<Issue>3</Issue>
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<MedlineDate>2001 May-Jun</MedlineDate>
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<Title>Annals of human biology</Title>
<ISOAbbreviation>Ann. Hum. Biol.</ISOAbbreviation>
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<ArticleTitle>Human mitochondrial DNA sequence variation in the Moroccan population of the Souss area.</ArticleTitle>
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<MedlinePgn>295-307</MedlinePgn>
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<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Various populations have contributed to the present-day gene pool of Morocco, including the autochthonous Berber population, Phoenicians, Sephardic Jews, Bedouin Arabs and sub-Saharan Africans.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The primary objective of the study was to complete a genetic description of the Berber-speaking population in the Souss region of southern Morocco, based on mitochondrial DNA (mtDNA) sequence analysis.</AbstractText>
<AbstractText Label="SUBJECTS AND METHODS" NlmCategory="METHODS">The first hypervariable segment of the mtDNA control region was sequenced in a sample of 50 individuals from the Souss Valley, and the results compared with the extensive body of data available on mtDNA sequence variation in Europe and sub-Saharan Africa.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Thirty-four different sequences were found: an estimated 68% of the sequences occurred throughout Europe, West Asia and North Africa, 26% originated in sub-Saharan Africa, and 6% belonged to the North African specific haplogroup U6. The Souss Valley mtDNA sequences indicated the presence of two populations which expanded at different times: the West Eurasian sequences in the Souss sample had a smaller average number of pairwise differences than pairs of sub-Saharan sequences.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Detailed knowledge of the possible geographic origin of each sequence facilitated an interpretation of both internal diversity parameters and between-population relationships. The sub-Saharan admixture in the Souss Valley matched the south-north cline of sub-Saharan influence in North Africa, also evident in the genetic distances of North African populations to Europeans and sub-Saharan Africans.</AbstractText>
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<Affiliation>Laboratoire de Biologic Cellulaire et Moléculaire, Faculté des Sciences, Université Ibnou-Zohr, Agadir, Morocco.</Affiliation>
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<Language>eng</Language>
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<PublicationType UI="D003160">Comparative Study</PublicationType>
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<DescriptorName UI="D009018" MajorTopicYN="N" Type="Geographic">Morocco</DescriptorName>
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<name sortKey="Akhayat, O" sort="Akhayat, O" uniqKey="Akhayat O" first="O" last="Akhayat">O. Akhayat</name>
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<name sortKey="Calafell, F" sort="Calafell, F" uniqKey="Calafell F" first="F" last="Calafell">F. Calafell</name>
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